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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 2
1969 1
1972 2
1973 1
1974 3
1975 4
1978 2
1979 3
1980 1
1981 2
1982 2
1983 1
1984 1
1985 1
1986 2
1987 1
1988 3
1989 1
1990 2
1992 3
1993 1
1994 1
1995 3
1996 2
1997 1
1998 2
1999 1
2000 5
2001 3
2002 8
2003 14
2004 6
2005 4
2006 4
2007 5
2008 7
2009 6
2010 9
2011 6
2012 7
2013 3
2014 3
2015 6
2016 3
2017 3
2018 6
2019 5
2020 7
2021 9
2022 5
2023 3
2024 0

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169 results

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Page 1
Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases.
Shibuya M. Shibuya M. J Biochem. 2013 Jan;153(1):13-9. doi: 10.1093/jb/mvs136. Epub 2012 Nov 21. J Biochem. 2013. PMID: 23172303 Free PMC article. Review.
VEGFR-2 exhibits a strong TK activity towards pro-angiogenic signals, whereas the soluble VEGFR-1 (sFlt-1) functions as an endogenous VEGF inhibitor. sFlt-1 is abnormally overexpressed in the placenta of preeclampsia patients, resulting in the major symptoms of the disease …
VEGFR-2 exhibits a strong TK activity towards pro-angiogenic signals, whereas the soluble VEGFR-1 (sFlt-1) functions as an endogenous VEGF i …
Relevance of ABC Transporters in Drug Development.
Nwabufo CK. Nwabufo CK. Curr Drug Metab. 2022;23(6):434-446. doi: 10.2174/1389200223666220621113524. Curr Drug Metab. 2022. PMID: 35726814 Review.
ATP-binding cassette (ABC) transporters play a critical role in protecting vital organs such as the brain and placenta against xenobiotics, as well as in modulating the pharmacological and toxicological profile of several drug candidates by restricting their penetration th …
ATP-binding cassette (ABC) transporters play a critical role in protecting vital organs such as the brain and placenta against xenobi …
Breast cancer, placenta and pregnancy.
Froehlich K, Schmidt A, Heger JI, Al-Kawlani B, Aberl CA, Jeschke U, Loibl S, Markert UR. Froehlich K, et al. Eur J Cancer. 2019 Jul;115:68-78. doi: 10.1016/j.ejca.2019.03.021. Epub 2019 May 20. Eur J Cancer. 2019. PMID: 31121525 Review.
Animal and human studies indicate that T cells are involved in these processes. Several placenta-derived factors, especially kisspeptin, have direct anti-tumour effects. The pregnancy-related increase of estrogen, progesterone, and other hormones influence growth and chara …
Animal and human studies indicate that T cells are involved in these processes. Several placenta-derived factors, especially kisspept …
ABCG2: a perspective.
Robey RW, To KK, Polgar O, Dohse M, Fetsch P, Dean M, Bates SE. Robey RW, et al. Adv Drug Deliv Rev. 2009 Jan 31;61(1):3-13. doi: 10.1016/j.addr.2008.11.003. Epub 2008 Dec 16. Adv Drug Deliv Rev. 2009. PMID: 19135109 Free PMC article. Review.
With high normal tissue expression in the brain endothelium, gastrointestinal tract, and placenta, ABCG2 is believed to be important in the protection from xenobiotics, regulating oral bioavailability, forming part of the blood-brain barrier, the blood-testis barrier, and …
With high normal tissue expression in the brain endothelium, gastrointestinal tract, and placenta, ABCG2 is believed to be important …
An update on expression and function of P-gp/ABCB1 and BCRP/ABCG2 in the placenta and fetus.
Han LW, Gao C, Mao Q. Han LW, et al. Expert Opin Drug Metab Toxicol. 2018 Aug;14(8):817-829. doi: 10.1080/17425255.2018.1499726. Epub 2018 Aug 3. Expert Opin Drug Metab Toxicol. 2018. PMID: 30010462 Free PMC article. Review.
Areas covered: Comprehensive literature review through PubMed (primarily from July 2010 to February 2018) on P-gp and BCRP expression and function in the placenta and fetus of primarily human, mouse, rat, and guinea pig. Expert opinion: While there are many commonalities i …
Areas covered: Comprehensive literature review through PubMed (primarily from July 2010 to February 2018) on P-gp and BCRP expression and fu …
ABCB1 and ABCG2 expression in the placenta and fetus: an interspecies comparison.
Myllynen P, Kummu M, Sieppi E. Myllynen P, et al. Expert Opin Drug Metab Toxicol. 2010 Nov;6(11):1385-98. doi: 10.1517/17425255.2010.514264. Epub 2010 Aug 26. Expert Opin Drug Metab Toxicol. 2010. PMID: 20738225 Review.
They are expressed, for example, in the intestine, liver, kidney, BBB and placenta. It has become evident that ABCB1 and ABCG2 modify the pharmaco/toxicokinetics in the placenta and fetus and may consequently affect the outcome of pregnancy. ...WHAT THE READER WILL …
They are expressed, for example, in the intestine, liver, kidney, BBB and placenta. It has become evident that ABCB1 and ABCG2 modify …
Immunological and functional aspects of MAGEA3 cancer/testis antigen.
Das B, Senapati S. Das B, et al. Adv Protein Chem Struct Biol. 2021;125:121-147. doi: 10.1016/bs.apcsb.2020.08.001. Epub 2020 Oct 1. Adv Protein Chem Struct Biol. 2021. PMID: 33931137 Review.
Identification of ectopic gene activation in cancer cells serves as a basis for both gene signature-guided tumor targeting and unearthing of oncogenic mechanisms to expand the understanding of tumor biology/oncogenic process. Proteins expressed only in germ cells of testis and/or …
Identification of ectopic gene activation in cancer cells serves as a basis for both gene signature-guided tumor targeting and unearthing of …
Regulation of Placental Efflux Transporters during Pregnancy Complications.
Kozlosky D, Barrett E, Aleksunes LM. Kozlosky D, et al. Drug Metab Dispos. 2022 Oct;50(10):1364-1375. doi: 10.1124/dmd.121.000449. Epub 2022 Jan 6. Drug Metab Dispos. 2022. PMID: 34992073 Free PMC article. Review.
The placenta is essential for regulating the exchange of solutes between the maternal and fetal circulations. As a result, the placenta offers support and protection to the developing fetus by delivering crucial nutrients and removing waste and xenobiotics. ...
The placenta is essential for regulating the exchange of solutes between the maternal and fetal circulations. As a result, the pla
Gestational trophoblastic neoplasia: Novelties and challenges.
Silva ALMD, Monteiro KDN, Sun SY, Borbely AU. Silva ALMD, et al. Placenta. 2021 Dec;116:38-42. doi: 10.1016/j.placenta.2021.02.013. Epub 2021 Feb 25. Placenta. 2021. PMID: 33685753 Review.
These malignancies are characterized as gestational trophoblastic neoplasm (GTN), rarer, although more dangerous. The diagnosis of GTN is made in most cases by monitoring serum chorionic gonadotropin (hCG) with histological confirmation. ...
These malignancies are characterized as gestational trophoblastic neoplasm (GTN), rarer, although more dangerous. The diagnosis of GT …
169 results