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Plasmodium infection alters Anopheles gambiae detoxification gene expression.
Félix RC, Müller P, Ribeiro V, Ranson H, Silveira H. Félix RC, et al. BMC Genomics. 2010 May 19;11:312. doi: 10.1186/1471-2164-11-312. BMC Genomics. 2010. PMID: 20482856 Free PMC article.
BACKGROUND: Anopheles gambiae has been shown to change its global gene expression patterns upon Plasmodium infection. ...In the fat body, while less dramatic, gene expression alterations were also observed and occurre …
BACKGROUND: Anopheles gambiae has been shown to change its global gene expression patterns upon Plasmodium …
Differential gene expression in Anopheles stephensi following infection with drug-resistant Plasmodium yoelii.
Zhang J, Huang J, Zhu F, Zhang J. Zhang J, et al. Parasit Vectors. 2017 Aug 29;10(1):401. doi: 10.1186/s13071-017-2326-y. Parasit Vectors. 2017. PMID: 28851458 Free PMC article.
At this point, little is known about the variations in mosquito immunity and metabolism when mosquitoes are infected with drug-resistant parasites. To understand the differential gene expression in Anopheles following infection with drug-resistant P …
At this point, little is known about the variations in mosquito immunity and metabolism when mosquitoes are infected with drug-resistant par …
The interplay between tubulins and P450 cytochromes during Plasmodium berghei invasion of Anopheles gambiae midgut.
Félix RC, Silveira H. Félix RC, et al. PLoS One. 2011;6(8):e24181. doi: 10.1371/journal.pone.0024181. Epub 2011 Aug 30. PLoS One. 2011. PMID: 21912622 Free PMC article.
BACKGROUND: Plasmodium infection increases the oxidative stress inside the mosquito, leading to a significant alteration on transcription of Anopheles gambiae detoxification genes. ...Further work is needed to fully understand the role of …
BACKGROUND: Plasmodium infection increases the oxidative stress inside the mosquito, leading to a significant alteration …
Genome-wide gene expression profiling reveals that cuticle alterations and P450 detoxification are associated with deltamethrin and DDT resistance in Anopheles arabiensis populations from Ethiopia.
Simma EA, Dermauw W, Balabanidou V, Snoeck S, Bryon A, Clark RM, Yewhalaw D, Vontas J, Duchateau L, Van Leeuwen T. Simma EA, et al. Pest Manag Sci. 2019 Jul;75(7):1808-1818. doi: 10.1002/ps.5374. Epub 2019 Apr 1. Pest Manag Sci. 2019. PMID: 30740870
BACKGROUND: Vector control is the main intervention in malaria control and elimination strategies. However, the development of insecticide resistance is one of the major challenges for controlling malaria vectors. ...RESULTS: Both RNAseq analysis and RT-qPCR showed …
BACKGROUND: Vector control is the main intervention in malaria control and elimination strategies. However, the development of insect …
RNA-seq analyses of changes in the Anopheles gambiae transcriptome associated with resistance to pyrethroids in Kenya: identification of candidate-resistance genes and candidate-resistance SNPs.
Bonizzoni M, Ochomo E, Dunn WA, Britton M, Afrane Y, Zhou G, Hartsel J, Lee MC, Xu J, Githeko A, Fass J, Yan G. Bonizzoni M, et al. Parasit Vectors. 2015 Sep 17;8:474. doi: 10.1186/s13071-015-1083-z. Parasit Vectors. 2015. PMID: 26381877 Free PMC article.
METHODS: The sequence-based technique RNA-seq was applied to study changes in the transcriptome of deltamethrin-resistant and -susceptible Anopheles gambiae mosquitoes from the Western Province of Kenya. The resulting gene expression profiles were comp …
METHODS: The sequence-based technique RNA-seq was applied to study changes in the transcriptome of deltamethrin-resistant and -susceptible …
Metabolic and target-site mechanisms combine to confer strong DDT resistance in Anopheles gambiae.
Mitchell SN, Rigden DJ, Dowd AJ, Lu F, Wilding CS, Weetman D, Dadzie S, Jenkins AM, Regna K, Boko P, Djogbenou L, Muskavitch MA, Ranson H, Paine MJ, Mayans O, Donnelly MJ. Mitchell SN, et al. PLoS One. 2014 Mar 27;9(3):e92662. doi: 10.1371/journal.pone.0092662. eCollection 2014. PLoS One. 2014. PMID: 24675797 Free PMC article.
In this study we demonstrate how resistance to DDT in the major African malaria vector Anopheles gambiae is a result of both target-site resistance mechanisms that have introgressed between incipient species (the M- and S-molecular forms) and allelic variants …
In this study we demonstrate how resistance to DDT in the major African malaria vector Anopheles gambiae is a result of …
Exploring mechanisms of multiple insecticide resistance in a population of the malaria vector Anopheles funestus in Benin.
Djouaka R, Irving H, Tukur Z, Wondji CS. Djouaka R, et al. PLoS One. 2011;6(11):e27760. doi: 10.1371/journal.pone.0027760. Epub 2011 Nov 16. PLoS One. 2011. PMID: 22110757 Free PMC article.
BACKGROUND: The insecticide resistance status of the malaria vector Anopheles funestus and the underlying resistance mechanisms remain uncharacterised in many parts of Africa, notably in Benin, West Africa. ...Biochemical assays revealed elevated levels of GSTs and …
BACKGROUND: The insecticide resistance status of the malaria vector Anopheles funestus and the underlying resistance mechanism …