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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1955 1
1957 1
1959 2
1962 1
1963 1
1964 1
1965 18
1966 29
1967 49
1968 67
1969 79
1970 80
1971 113
1972 101
1973 87
1974 122
1975 135
1976 128
1977 136
1978 171
1979 195
1980 256
1981 257
1982 255
1983 296
1984 333
1985 416
1986 407
1987 399
1988 403
1989 551
1990 572
1991 610
1992 586
1993 628
1994 609
1995 625
1996 652
1997 646
1998 608
1999 702
2000 671
2001 669
2002 718
2003 736
2004 796
2005 952
2006 900
2007 964
2008 1012
2009 1047
2010 1109
2011 1184
2012 1126
2013 1199
2014 1111
2015 1116
2016 1128
2017 1169
2018 1148
2019 1209
2020 1269
2021 1242
2022 817
2023 780
2024 1001
2025 1547
2026 854

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35,706 results

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Page 1
Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies.
Kaur R, Kaur M, Singh J. Kaur R, et al. Cardiovasc Diabetol. 2018 Aug 31;17(1):121. doi: 10.1186/s12933-018-0763-3. Cardiovasc Diabetol. 2018. PMID: 30170601 Free PMC article. Review.
All these evidences are supported by the clinical trials reporting the importance of endothelial dysfunction and platelet hyperactivity in the pathogenesis of atherosclerotic vascular complications. In this review, an attempt has been made to comprehensively compile …
All these evidences are supported by the clinical trials reporting the importance of endothelial dysfunction and platelet hype …
Platelet mitochondrial dysfunction and the correlation with human diseases.
Wang L, Wu Q, Fan Z, Xie R, Wang Z, Lu Y. Wang L, et al. Biochem Soc Trans. 2017 Dec 15;45(6):1213-1223. doi: 10.1042/BST20170291. Epub 2017 Oct 20. Biochem Soc Trans. 2017. PMID: 29054925 Review.
Different lines of studies have demonstrated that mitochondria in platelets have function far more than thrombogenesis regulation, and beyond hemostasis, platelet mitochondrial dysfunction has also been used for studying mitochondrial-related diseases. ...Alo …
Different lines of studies have demonstrated that mitochondria in platelets have function far more than thrombogenesis regulation, an …
Platelet Physiology.
Gremmel T, Frelinger AL 3rd, Michelson AD. Gremmel T, et al. Semin Thromb Hemost. 2016 Apr;42(3):191-204. doi: 10.1055/s-0035-1564835. Epub 2016 Feb 29. Semin Thromb Hemost. 2016. PMID: 26926581 Review.
Platelets are the smallest blood cells, numbering 150 to 350 10(9)/L in healthy individuals. ...This review provides an overview of platelet physiology focusing particularly on the structure, granules, surface glycoproteins, and activation pathways of pl …
Platelets are the smallest blood cells, numbering 150 to 350 10(9)/L in healthy individuals. ...This review provides an over …
[Thrombosis and platelet dysfunction in myeloproliferative neoplasms].
Mornet C, Galinat H, Mingant F, Ianotto JC, Lippert E. Mornet C, et al. Rev Med Interne. 2020 May;41(5):319-324. doi: 10.1016/j.revmed.2019.12.013. Epub 2020 Jan 31. Rev Med Interne. 2020. PMID: 32008800 Review. French.
The pathophysiology of these thromboses is complex and involves different actors: blood cells, endothelium and flow conditions. Numerous studies have been conducted to identify risk factors for thrombosis. ...Haemorrhagic manifestations, less frequent than thrombosis, are …
The pathophysiology of these thromboses is complex and involves different actors: blood cells, endothelium and flow conditions. Numer …
Analysis of platelet function and dysfunction.
Jurk K. Jurk K. Hamostaseologie. 2015;35(1):60-72. doi: 10.5482/HAMO-14-09-0047. Epub 2014 Dec 8. Hamostaseologie. 2015. PMID: 25482925 Review.
Multiple activation processes and complex signalling networks are responsible for appropriate platelet function. Thus, a variety of platelet function tests are available for platelet research and diagnosis of platelet dysfunction. ...Based on th …
Multiple activation processes and complex signalling networks are responsible for appropriate platelet function. Thus, a variety of …
Platelet dysfunction in type 2 diabetes.
Vinik AI, Erbas T, Park TS, Nolan R, Pittenger GL. Vinik AI, et al. Diabetes Care. 2001 Aug;24(8):1476-85. doi: 10.2337/diacare.24.8.1476. Diabetes Care. 2001. PMID: 11473089 Review.
These complications are associated with dysfunction of platelets and the neurovascular unit. Platelets are essential for hemostasis, and knowledge of their function is basic to understanding the pathophysiology of vascular disease in diabetes. Intact healthy …
These complications are associated with dysfunction of platelets and the neurovascular unit. Platelets are essential fo …
Platelet dysfunction in Chediak-Higashi syndrome-affected cattle.
Shiraishi M, Ogawa H, Ikeda M, Kawashima S, Ito K. Shiraishi M, et al. J Vet Med Sci. 2002 Sep;64(9):751-60. doi: 10.1292/jvms.64.751. J Vet Med Sci. 2002. PMID: 12399597 Free article. Review.
However, these endogenous agonists play only a minor role in collagen-induced aggregation of bovine platelets. More importantly, activation of phospholipase C as a result of a direct action of collagen is depressed, leading to a depression of Ca(2+) mobilization, in pla …
However, these endogenous agonists play only a minor role in collagen-induced aggregation of bovine platelets. More importantly, acti …
Platelet-mediated vascular dysfunction during acute lung injury.
Dixon JT, Gozal E, Roberts AM. Dixon JT, et al. Arch Physiol Biochem. 2012 May;118(2):72-82. doi: 10.3109/13813455.2012.665463. Epub 2012 Mar 23. Arch Physiol Biochem. 2012. PMID: 22439828 Review.
OBJECTIVE: This review focuses on platelet mechanisms of vascular dysfunction in the lung and presents a hypothesis for interplay between platelet activation, endothelial damage and fibrinogen. The purpose is to discuss current knowledge regarding mechanisms …
OBJECTIVE: This review focuses on platelet mechanisms of vascular dysfunction in the lung and presents a hypothesis for interp …
Acquired platelet disorders.
Casari C, Bergmeier W. Casari C, et al. Thromb Res. 2016 May;141 Suppl 2:S73-5. doi: 10.1016/S0049-3848(16)30371-1. Thromb Res. 2016. PMID: 27207431 Review.
In contrast to congenital platelet disorders, which are rare, acquired platelet dysfunctions are more common in clinical practice. ...We here provide a short overview of the various forms of acquired platelet disorders, with a particular focus on recen …
In contrast to congenital platelet disorders, which are rare, acquired platelet dysfunctions are more common in clinica …
Platelet dysfunction in central obesity.
Anfossi G, Russo I, Trovati M. Anfossi G, et al. Nutr Metab Cardiovasc Dis. 2009 Jul;19(6):440-9. doi: 10.1016/j.numecd.2009.01.006. Epub 2009 Apr 5. Nutr Metab Cardiovasc Dis. 2009. PMID: 19346117 Review.
A major role in the increased cardiovascular risk is played by platelets, which show an increased activation and a reduced sensitivity to the physiological and pharmacological antiaggregating agents. This review focuses on platelet dysfunction in central obes …
A major role in the increased cardiovascular risk is played by platelets, which show an increased activation and a reduced sensitivit …
35,706 results
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