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202 results
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Lipids on trial: the search for the offending metabolite in Niemann-Pick type C disease.
Lloyd-Evans E, Platt FM. Lloyd-Evans E, et al. Among authors: platt fm. Traffic. 2010 Apr;11(4):419-28. doi: 10.1111/j.1600-0854.2010.01032.x. Epub 2010 Jan 6. Traffic. 2010. PMID: 20059748 Review.
New therapeutic prospects for the glycosphingolipid lysosomal storage diseases.
Platt FM, Butters TD. Platt FM, et al. Biochem Pharmacol. 1998 Aug 15;56(4):421-30. doi: 10.1016/s0006-2952(98)00115-4. Biochem Pharmacol. 1998. PMID: 9763217 Review.
Inhibition of substrate synthesis as a strategy for glycolipid lysosomal storage disease therapy.
Platt FM, Jeyakumar M, Andersson U, Priestman DA, Dwek RA, Butters TD, Cox TM, Lachmann RH, Hollak C, Aerts JM, Van Weely S, HrebĂ­cek M, Moyses C, Gow I, Elstein D, Zimran A. Platt FM, et al. J Inherit Metab Dis. 2001 Apr;24(2):275-90. doi: 10.1023/a:1010335505357. J Inherit Metab Dis. 2001. PMID: 11405346 Review.
Increased glycosphingolipid levels in serum and aortae of apolipoprotein E gene knockout mice.
Garner B, Priestman DA, Stocker R, Harvey DJ, Butters TD, Platt FM. Garner B, et al. Among authors: platt fm. J Lipid Res. 2002 Feb;43(2):205-14. J Lipid Res. 2002. PMID: 11861662
Targeting glycosylation as a therapeutic approach.
Dwek RA, Butters TD, Platt FM, Zitzmann N. Dwek RA, et al. Among authors: platt fm. Nat Rev Drug Discov. 2002 Jan;1(1):65-75. doi: 10.1038/nrd708. Nat Rev Drug Discov. 2002. PMID: 12119611 Review.
Glucosylceramide modulates membrane traffic along the endocytic pathway.
Sillence DJ, Puri V, Marks DL, Butters TD, Dwek RA, Pagano RE, Platt FM. Sillence DJ, et al. Among authors: platt fm. J Lipid Res. 2002 Nov;43(11):1837-45. doi: 10.1194/jlr.m200232-jlr200. J Lipid Res. 2002. PMID: 12401882
Substrate deprivation: a new therapeutic approach for the glycosphingolipid lysosomal storage diseases.
Platt FM, Butters TD. Platt FM, et al. Expert Rev Mol Med. 2000 Feb 1;2(1):1-17. doi: 10.1017/S1462399400001484. Expert Rev Mol Med. 2000. PMID: 14585134
New therapeutics for the treatment of glycosphingolipid lysosomal storage diseases.
Butters TD, Dwek RA, Platt FM. Butters TD, et al. Among authors: platt fm. Adv Exp Med Biol. 2003;535:219-26. doi: 10.1007/978-1-4615-0065-0_14. Adv Exp Med Biol. 2003. PMID: 14714898 Review.
Accumulation of glycosphingolipids in Niemann-Pick C disease disrupts endosomal transport.
te Vruchte D, Lloyd-Evans E, Veldman RJ, Neville DC, Dwek RA, Platt FM, van Blitterswijk WJ, Sillence DJ. te Vruchte D, et al. Among authors: platt fm. J Biol Chem. 2004 Jun 18;279(25):26167-75. doi: 10.1074/jbc.M311591200. Epub 2004 Apr 12. J Biol Chem. 2004. PMID: 15078881
Glycosphingolipids in endocytic membrane transport.
Sillence DJ, Platt FM. Sillence DJ, et al. Among authors: platt fm. Semin Cell Dev Biol. 2004 Aug;15(4):409-16. doi: 10.1016/j.semcdb.2004.03.004. Semin Cell Dev Biol. 2004. PMID: 15207831 Review.
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