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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1985 1
1987 1
1988 1
1991 1
1994 3
1995 2
1996 3
1997 6
1998 4
1999 7
2000 4
2001 4
2002 6
2003 8
2004 4
2005 5
2006 4
2007 9
2008 7
2009 8
2010 5
2011 16
2012 8
2013 8
2014 9
2015 13
2016 15
2017 10
2018 14
2019 9
2020 8
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181 results
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Plectin-1 Targeted Dual-modality Nanoparticles for Pancreatic Cancer Imaging.
Chen X, Zhou H, Li X, Duan N, Hu S, Liu Y, Yue Y, Song L, Zhang Y, Li D, Wang Z. Chen X, et al. EBioMedicine. 2018 Apr;30:129-137. doi: 10.1016/j.ebiom.2018.03.008. Epub 2018 Mar 15. EBioMedicine. 2018. PMID: 29574092 Free PMC article.
BACKGROUND: Biomarker-targeted molecular imaging holds promise for early detection of pancreatic cancer. The aim of this study was to design and evaluate a plectin-1 targeted multi-functional nanoparticle probe for pancreatic cancer imaging. ...CONCLUSIONS: O …
BACKGROUND: Biomarker-targeted molecular imaging holds promise for early detection of pancreatic cancer. The aim of this study was to …
Plectin-targeted liposomes enhance the therapeutic efficacy of a PARP inhibitor in the treatment of ovarian cancer.
Dasa SSK, Diakova G, Suzuki R, Mills AM, Gutknecht MF, Klibanov AL, Slack-Davis JK, Kelly KA. Dasa SSK, et al. Theranostics. 2018 Apr 11;8(10):2782-2798. doi: 10.7150/thno.23050. eCollection 2018. Theranostics. 2018. PMID: 29774075 Free PMC article.
This cancer specific phenotype allowed us to image pancreatic cancer successfully using plectin targeted peptide (PTP) conjugated to nanoparticles or displayed on capsid protein of adeno-associated virus (AAV) particles. ...Methods: Plectin expression …
This cancer specific phenotype allowed us to image pancreatic cancer successfully using plectin targeted peptide (PTP) …
A novel plectin/integrin-targeted bispecific molecular probe for magnetic resonance/near-infrared imaging of pancreatic cancer.
Wang Q, Yan H, Jin Y, Wang Z, Huang W, Qiu J, Kang F, Wang K, Zhao X, Tian J. Wang Q, et al. Biomaterials. 2018 Nov;183:173-184. doi: 10.1016/j.biomaterials.2018.08.048. Epub 2018 Aug 26. Biomaterials. 2018. PMID: 30172243
In this study, we have developed a novel conjugate complex of plectin/integrin-targeted bispecific molecular probe, termed Gd-Cy7-PTP/RGD, to be used for magnetic resonance/near-infrared imaging (MRI/NIRF) of pancreatic cancer in vivo. ...Moreover, such bispecific m …
In this study, we have developed a novel conjugate complex of plectin/integrin-targeted bispecific molecular probe, termed Gd-Cy7-PTP …
Unbiased peptoid combinatorial cell screen identifies plectin protein as a potential biomarker for lung cancer stem cells.
Raymond AC, Gao B, Girard L, Minna JD, Gomika Udugamasooriya D. Raymond AC, et al. Sci Rep. 2019 Oct 18;9(1):14954. doi: 10.1038/s41598-019-51004-3. Sci Rep. 2019. PMID: 31628412 Free PMC article.
To develop new approaches to detecting and targeting lung cancer CSCs, we applied an "unbiased" peptoid combinatorial cell screen to identify highly specific ligands that bind a CSC subpopulation of non-small cell lung cancer cells (defined by Aldefluor positivity), …
To develop new approaches to detecting and targeting lung cancer CSCs, we applied an "unbiased" peptoid combinatorial cell screen to …
Plectin deficiency in liver cancer cells promotes cell migration and sensitivity to sorafenib treatment.
Cheng CC, Chao WT, Liao CC, Tseng YH, Lai YC, Lai YS, Hsu YH, Liu YH. Cheng CC, et al. Cell Adh Migr. 2018 Jan 2;12(1):19-27. doi: 10.1080/19336918.2017.1288789. Epub 2017 Feb 17. Cell Adh Migr. 2018. PMID: 28276928 Free PMC article.
Plectin involved in activation of kinases in cell signaling pathway and plays important role in cell morphology and migration. ...The drug sensitivity to sorafenib treatment showed inverse correlation with the expression of plectin. We suggest that plectin de
Plectin involved in activation of kinases in cell signaling pathway and plays important role in cell morphology and migration. ...The
Typing of pancreatic cancer-associated fibroblasts identifies different subpopulations.
Nielsen MFB, Mortensen MB, Detlefsen S. Nielsen MFB, et al. World J Gastroenterol. 2018 Nov 7;24(41):4663-4678. doi: 10.3748/wjg.v24.i41.4663. World J Gastroenterol. 2018. PMID: 30416314 Free PMC article.
AIM: To determine whether it is possible to identify different immune phenotypic subpopulations of cancer-associated fibroblasts (CAFs) in pancreatic cancer (PC). ...Galectin-1 was stronger expressed in j-CAFs vs septal fibroblasts, PDGF-Rβ, tissue transglutaminase …
AIM: To determine whether it is possible to identify different immune phenotypic subpopulations of cancer-associated fibroblasts (CAF …
Plectin promotes migration and invasion of cancer cells and is a novel prognostic marker for head and neck squamous cell carcinoma.
Katada K, Tomonaga T, Satoh M, Matsushita K, Tonoike Y, Kodera Y, Hanazawa T, Nomura F, Okamoto Y. Katada K, et al. J Proteomics. 2012 Mar 16;75(6):1803-15. doi: 10.1016/j.jprot.2011.12.018. Epub 2011 Dec 30. J Proteomics. 2012. PMID: 22245045
We identified 65 proteins which were significantly increased or decreased in the tumors by 2D-DIGE using 12 HNSCC and adjacent non-cancer tissues. Western blotting and immunohistochemical analysis confirmed that the expression of plectin was significantly increased …
We identified 65 proteins which were significantly increased or decreased in the tumors by 2D-DIGE using 12 HNSCC and adjacent non-cancer
Vimentin intermediate filament and plectin provide a scaffold for invadopodia, facilitating cancer cell invasion and extravasation for metastasis.
Sutoh Yoneyama M, Hatakeyama S, Habuchi T, Inoue T, Nakamura T, Funyu T, Wiche G, Ohyama C, Tsuboi S. Sutoh Yoneyama M, et al. Eur J Cell Biol. 2014 Apr;93(4):157-69. doi: 10.1016/j.ejcb.2014.03.002. Epub 2014 Apr 15. Eur J Cell Biol. 2014. PMID: 24810881 Free article.
Here we report a novel role of vimentin IF and plectin in metastasis. In invasive bladder cancer cells, the vimentin IF-plectin-invadopodia F-actin link was formed. ...Our results suggest that plectin anchoring invadopodia to vimentin IF scaffolds and …
Here we report a novel role of vimentin IF and plectin in metastasis. In invasive bladder cancer cells, the vimentin IF-ple
Plectin-1 as a Biomarker of Malignant Progression in Intraductal Papillary Mucinous Neoplasms: A Multicenter Study.
Moris M, Dawson DW, Jiang J, Lewis J, Nassar A, Takeuchi KK, Lay AR, Zhai Q, Donahue TR, Kelly KA, Crawford HC, Wallace M. Moris M, et al. Pancreas. 2016 Oct;45(9):1353-8. doi: 10.1097/MPA.0000000000000652. Pancreas. 2016. PMID: 27101571 Free PMC article.
OBJECTIVE: This study aimed to evaluate Plectin-1 expression as a biomarker of malignant risk for intraductal papillary mucinous neoplasms (IPMNs). ...RESULTS: Plectin-1 expression was increased in invasive adenocarcinoma compared with adjacent in situ IPMN ( …
OBJECTIVE: This study aimed to evaluate Plectin-1 expression as a biomarker of malignant risk for intraductal papillary mucinous n
The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated tubulin acetylation.
Kasai N, Kadeer A, Kajita M, Saitoh S, Ishikawa S, Maruyama T, Fujita Y. Kasai N, et al. Sci Rep. 2018 Feb 1;8(1):2097. doi: 10.1038/s41598-018-20146-1. Sci Rep. 2018. PMID: 29391412 Free PMC article.
During this cancer preventive process, cytoskeletal proteins plectin and Epithelial Protein Lost In Neoplasm (EPLIN) are accumulated in RasV12 cells that are surrounded by normal cells, which positively regulate the apical elimination of transformed cells. ...This s …
During this cancer preventive process, cytoskeletal proteins plectin and Epithelial Protein Lost In Neoplasm (EPLIN) are accum …
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