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Anti-SARS-CoV-2 antibodies in a nasal spray efficiently block viral transmission between ferrets.
Gildemann K, Tsernant ML, Liivand L, Ennomäe R, Poikalainen V, Lepasalu L, Rom S, Kavak A, Cox RM, Wolf JD, Lieber CM, Plemper RK, Männik A, Ustav M Jr, Ustav M, Gerhold JM. Gildemann K, et al. Among authors: plemper rk. iScience. 2024 Jun 20;27(7):110326. doi: 10.1016/j.isci.2024.110326. eCollection 2024 Jul 19. iScience. 2024. PMID: 39045097 Free PMC article.
Paxlovid-like nirmatrelvir/ritonavir fails to block SARS-CoV-2 transmission in ferrets.
Cox RM, Lieber CM, Wolf JD, Karimi A, Lieberman NAP, Sticher ZM, Roychoudhury P, Andrews MK, Krueger RE, Natchus MG, Painter GR, Kolykhalov AA, Greninger AL, Plemper RK. Cox RM, et al. Among authors: plemper rk. bioRxiv [Preprint]. 2022 Nov 21:2022.11.20.517271. doi: 10.1101/2022.11.20.517271. bioRxiv. 2022. PMID: 36451893 Free PMC article. Preprint.
SARS-CoV-2 variant of concern type and biological sex affect efficacy of molnupiravir in dwarf hamster model of severe COVID-19.
Lieber CM, Cox RM, Sourimant J, Wolf JD, Juergens K, Phung Q, Saindane MT, Natchus MG, Painter GR, Sakamoto K, Greninger AL, Plemper RK. Lieber CM, et al. Among authors: plemper rk. bioRxiv [Preprint]. 2022 Feb 7:2022.02.04.479171. doi: 10.1101/2022.02.04.479171. bioRxiv. 2022. Update in: Nat Commun. 2022 Jul 29;13(1):4416. doi: 10.1038/s41467-022-32045-1 PMID: 35169793 Free PMC article. Updated. Preprint.
4'-Fluorouridine is a broad-spectrum orally efficacious antiviral blocking respiratory syncytial virus and SARS-CoV-2 replication.
Sourimant J, Lieber CM, Aggarwal M, Cox RM, Wolf JD, Yoon JJ, Toots M, Ye C, Sticher Z, Kolykhalov AA, Martinez-Sobrido L, Bluemling GR, Natchus MG, Painter GR, Plemper RK. Sourimant J, et al. Among authors: plemper rk. bioRxiv [Preprint]. 2021 May 20:2021.05.19.444875. doi: 10.1101/2021.05.19.444875. bioRxiv. 2021. Update in: Science. 2022 Jan 14;375(6577):161-167. doi: 10.1126/science.abj5508 PMID: 34031658 Free PMC article. Updated. Preprint.
Influenza A virus resistance to 4'-fluorouridine coincides with viral attenuation in vitro and in vivo.
Lieber CM, Kang HJ, Aggarwal M, Lieberman NA, Sobolik EB, Yoon JJ, Natchus MG, Cox RM, Greninger AL, Plemper RK. Lieber CM, et al. Among authors: plemper rk. bioRxiv [Preprint]. 2023 Oct 21:2023.10.20.563370. doi: 10.1101/2023.10.20.563370. bioRxiv. 2023. Update in: PLoS Pathog. 2024 Feb 1;20(2):e1011993. doi: 10.1371/journal.ppat.1011993 PMID: 37905070 Free PMC article. Updated. Preprint.
Tetracistronic Minigenomes Elucidate a Functional Promoter for Ghana Virus and Unveils Cedar Virus Replicase Promiscuity for all Henipaviruses.
Haas GD, Schmitz KS, Azarm KD, Johnson KN, Klain WR, Freiberg AN, Cox RM, Plemper RK, Lee B. Haas GD, et al. Among authors: plemper rk. bioRxiv [Preprint]. 2024 Apr 16:2024.04.16.589704. doi: 10.1101/2024.04.16.589704. bioRxiv. 2024. Update in: J Virol. 2024 Oct 22;98(10):e0080624. doi: 10.1128/jvi.00806-24 PMID: 38659760 Free PMC article. Updated. Preprint.
Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection.
Ngo VL, Lieber CM, Kang HJ, Sakamoto K, Kuczma M, Plemper RK, Gewirtz AT. Ngo VL, et al. Among authors: plemper rk. bioRxiv [Preprint]. 2024 Jan 13:2023.09.21.558814. doi: 10.1101/2023.09.21.558814. bioRxiv. 2024. Update in: Cell Host Microbe. 2024 Mar 13;32(3):335-348.e8. doi: 10.1016/j.chom.2024.01.002 PMID: 37790571 Free PMC article. Updated. Preprint.
Immunization with recombinant accessory protein-deficient SARS-CoV-2 protects against lethal challenge and viral transmission.
Ye C, Park JG, Chiem K, Dravid P, Allué-Guardia A, Garcia-Vilanova A, Kapoor A, Walter MR, Kobie JJ, Plemper RK, Torrelles JB, Martinez-Sobrido L. Ye C, et al. Among authors: plemper rk. bioRxiv [Preprint]. 2022 Mar 14:2022.03.13.484172. doi: 10.1101/2022.03.13.484172. bioRxiv. 2022. Update in: Microbiol Spectr. 2023 Jun 15;11(3):e0065323. doi: 10.1128/spectrum.00653-23 PMID: 35313573 Free PMC article. Updated. Preprint.
146 results