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GWASs and the age of human as the model organism for autoimmune genetic research.
Plenge R. Plenge R. Genome Biol. 2010;11(5):212. doi: 10.1186/gb-2010-11-5-212. Epub 2010 May 5. Genome Biol. 2010. PMID: 20441610 Free PMC article.
A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk.
Yarwood A, Han B, Raychaudhuri S, Bowes J, Lunt M, Pappas DA, Kremer J, Greenberg JD, Plenge R; Rheumatoid Arthritis Consortium International (RACI), Worthington J, Barton A, Eyre S. Yarwood A, et al. Among authors: plenge r. Ann Rheum Dis. 2015 Jan;74(1):170-6. doi: 10.1136/annrheumdis-2013-204133. Epub 2013 Oct 3. Ann Rheum Dis. 2015. PMID: 24092415 Free PMC article.
Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study.
Yarwood A, Viatte S, Okada Y, Plenge R, Yamamoto K; BRAGGSS, RACI, Barton A, Symmons D, Raychaudhuri S, Klareskog L, Gregersen P, Worthington J, Eyre S. Yarwood A, et al. Among authors: plenge r. Ann Rheum Dis. 2016 Jan;75(1):317-20. doi: 10.1136/annrheumdis-2014-207210. Epub 2015 Sep 17. Ann Rheum Dis. 2016. PMID: 26386125 Free PMC article.
Lack of gene-diuretic interactions on the risk of incident gout: the Nurses' Health Study and Health Professionals Follow-up Study.
Bao Y, Curhan G, Merriman T, Plenge R, Kraft P, Choi HK. Bao Y, et al. Among authors: plenge r. Ann Rheum Dis. 2015 Jul;74(7):1394-8. doi: 10.1136/annrheumdis-2014-206534. Epub 2015 Feb 9. Ann Rheum Dis. 2015. PMID: 25667207 Free PMC article.
Allele-specific methylation occurs at genetic variants associated with complex disease.
Hutchinson JN, Raj T, Fagerness J, Stahl E, Viloria FT, Gimelbrant A, Seddon J, Daly M, Chess A, Plenge R. Hutchinson JN, et al. Among authors: plenge r. PLoS One. 2014 Jun 9;9(6):e98464. doi: 10.1371/journal.pone.0098464. eCollection 2014. PLoS One. 2014. PMID: 24911414 Free PMC article.
Identification of secreted phosphoprotein 1 gene as a new rheumatoid arthritis susceptibility gene.
Gazal S, Sacre K, Allanore Y, Teruel M, Goodall AH; (The CARDIOGENICS consortium), Tohma S, Alfredsson L, Okada Y, Xie G, Constantin A, Balsa A, Kawasaki A, Nicaise P, Amos C, Rodriguez-Rodriguez L, Chiocchia G, Boileau C, Zhang J, Vittecoq O, Barnetche T, Gonzalez Gay MA, Furukawa H, Cantagrel A, Le Loët X, Sumida T, Hurtado-Nedelec M, Richez C, Chollet-Martin S, Schaeverbeke T, Combe B, Khoryati L, Coustet B, El-Benna J, Siminovitch K, Plenge R, Padyukov L, Martin J, Tsuchiya N, Dieudé P. Gazal S, et al. Among authors: plenge r. Ann Rheum Dis. 2015 Mar;74(3):e19. doi: 10.1136/annrheumdis-2013-204581. Epub 2014 Jan 21. Ann Rheum Dis. 2015. PMID: 24448344
Integrating autoimmune risk loci with gene-expression data identifies specific pathogenic immune cell subsets.
Hu X, Kim H, Stahl E, Plenge R, Daly M, Raychaudhuri S. Hu X, et al. Among authors: plenge r. Am J Hum Genet. 2011 Oct 7;89(4):496-506. doi: 10.1016/j.ajhg.2011.09.002. Epub 2011 Sep 29. Am J Hum Genet. 2011. PMID: 21963258 Free PMC article.
Identifying susceptibility genes for immunological disorders: patterns, power, and proof.
Plenge R, Rioux JD. Plenge R, et al. Immunol Rev. 2006 Apr;210:40-51. doi: 10.1111/j.0105-2896.2006.00372.x. Immunol Rev. 2006. PMID: 16623763 Review.
Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking.
Costenbader KH, Chang SC, De Vivo I, Plenge R, Karlson EW. Costenbader KH, et al. Among authors: plenge r. Arthritis Res Ther. 2008;10(3):R52. doi: 10.1186/ar2421. Epub 2008 May 7. Arthritis Res Ther. 2008. PMID: 18462498 Free PMC article.
Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.
Sieberts SK, Zhu F, García-García J, Stahl E, Pratap A, Pandey G, Pappas D, Aguilar D, Anton B, Bonet J, Eksi R, Fornés O, Guney E, Li H, Marín MA, Panwar B, Planas-Iglesias J, Poglayen D, Cui J, Falcao AO, Suver C, Hoff B, Balagurusamy VSK, Dillenberger D, Neto EC, Norman T, Aittokallio T, Ammad-Ud-Din M, Azencott CA, Bellón V, Boeva V, Bunte K, Chheda H, Cheng L, Corander J, Dumontier M, Goldenberg A, Gopalacharyulu P, Hajiloo M, Hidru D, Jaiswal A, Kaski S, Khalfaoui B, Khan SA, Kramer ER, Marttinen P, Mezlini AM, Molparia B, Pirinen M, Saarela J, Samwald M, Stoven V, Tang H, Tang J, Torkamani A, Vert JP, Wang B, Wang T, Wennerberg K, Wineinger NE, Xiao G, Xie Y, Yeung R, Zhan X, Zhao C; Members of the Rheumatoid Arthritis Challenge Consortium, Greenberg J, Kremer J, Michaud K, Barton A, Coenen M, Mariette X, Miceli C, Shadick N, Weinblatt M, de Vries N, Tak PP, Gerlag D, Huizinga TWJ, Kurreeman F, Allaart CF, Louis Bridges S Jr, Criswell L, Moreland L, Klareskog L, Saevarsdottir S, Padyukov L, Gregersen PK, Friend S, Plenge R, Stolovitzky G, Oliva B, Guan Y, Mangravite LM. Sieberts SK, et al. Among authors: plenge r. Nat Commun. 2016 Aug 23;7:12460. doi: 10.1038/ncomms12460. Nat Commun. 2016. PMID: 27549343 Free PMC article.
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