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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1912 1
1946 1
1949 1
1950 1
1951 1
1953 1
1954 4
1955 2
1956 3
1958 1
1959 1
1961 3
1962 1
1964 3
1965 1
1966 1
1967 1
1968 1
1969 4
1970 3
1972 4
1973 2
1974 1
1975 2
1977 7
1978 5
1979 8
1980 5
1981 3
1982 4
1983 5
1984 3
1985 7
1986 7
1987 7
1988 9
1989 11
1990 7
1991 9
1992 6
1993 15
1994 16
1995 15
1996 20
1997 19
1998 21
1999 24
2000 22
2001 17
2002 23
2003 37
2004 33
2005 32
2006 41
2007 43
2008 51
2009 40
2010 60
2011 57
2012 58
2013 70
2014 52
2015 48
2016 60
2017 74
2018 63
2019 71
2020 96
2021 99
2022 93
2023 97
2024 97
2025 40

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1,571 results

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Page 1
Exuberant Plexiform Neurofibroma.
Correia C, Reis M, Filipe P. Correia C, et al. Acta Med Port. 2023 Dec 4;36(12):846-847. doi: 10.20344/amp.19477. Epub 2023 May 19. Acta Med Port. 2023. PMID: 37205744 Free article. No abstract available.
Multiple Nf1 Schwann cell populations reprogram the plexiform neurofibroma tumor microenvironment.
Kershner LJ, Choi K, Wu J, Zhang X, Perrino M, Salomonis N, Shern JF, Ratner N. Kershner LJ, et al. JCI Insight. 2022 Sep 22;7(18):e154513. doi: 10.1172/jci.insight.154513. JCI Insight. 2022. PMID: 36134665 Free PMC article.
Affected individuals develop neurofibromas, benign tumors driven by NF1 loss in Schwann cells (SCs). By comparing normal nerve cells to plexiform neurofibroma (PN) cells using single-cell and bulk RNA sequencing, we identified changes in 5 SC populations, including …
Affected individuals develop neurofibromas, benign tumors driven by NF1 loss in Schwann cells (SCs). By comparing normal nerve cells to p
Safety and efficacy of selumetinib in pediatric and adult patients with neurofibromatosis type 1 and plexiform neurofibroma.
Kim H, Yoon HM, Kim EK, Ra YS, Kim HW, Yum MS, Kim MJ, Baek JS, Sung YS, Lee SM, Lim HS, Lee BJ, Lim HT, Kim D, Yoon J, Bae H, Hwang S, Choi YH, Kim KA, Choi IH, Lee SW, Park SJ, Lee BH. Kim H, et al. Neuro Oncol. 2024 Dec 5;26(12):2352-2363. doi: 10.1093/neuonc/noae121. Neuro Oncol. 2024. PMID: 38975694 Free PMC article. Clinical Trial.
BACKGROUND: The MEK inhibitor, selumetinib, reduces plexiform neurofibroma (PN) in pediatric patients with neurofibromatosis type 1 (NF1). Its safety and efficacy in adults with PN and effectiveness in other NF1 manifestations (eg, neurocognitive function, growth re …
BACKGROUND: The MEK inhibitor, selumetinib, reduces plexiform neurofibroma (PN) in pediatric patients with neurofibromatosis t …
Plexiform neurofibroma of the uterus.
Rogers D. Rogers D. Arch Gynecol Obstet. 2022 Feb;305(2):535-536. doi: 10.1007/s00404-021-06341-y. Epub 2021 Nov 28. Arch Gynecol Obstet. 2022. PMID: 34839387 No abstract available.
A phase 2 study of trametinib for patients with pediatric glioma or plexiform neurofibroma with refractory tumor and activation of the MAPK/ERK pathway: TRAM-01.
Perreault S, Larouche V, Tabori U, Hawkin C, Lippé S, Ellezam B, Décarie JC, Théoret Y, Métras MÉ, Sultan S, Cantin É, Routhier MÈ, Caru M, Legault G, Bouffet É, Lafay-Cousin L, Hukin J, Erker C, Jabado N. Perreault S, et al. BMC Cancer. 2019 Dec 27;19(1):1250. doi: 10.1186/s12885-019-6442-2. BMC Cancer. 2019. PMID: 31881853 Free PMC article.
The same pathway is also activated in plexiform neurofibromas (PNs) which are low-grade tumors involving peripheral nerves in patients with neurofibromatosis type 1 (NF1). ...Group 1 includes NF1 patients with progressing/refractory glioma. Group 2 includes NF1 patients wi …
The same pathway is also activated in plexiform neurofibromas (PNs) which are low-grade tumors involving peripheral nerves in patient …
Plexiform neurofibroma.
Bakshi SS. Bakshi SS. Cleve Clin J Med. 2016 Nov;83(11):792. doi: 10.3949/ccjm.83a.16002. Cleve Clin J Med. 2016. PMID: 27824540 Free article. No abstract available.
Mesenteric plexiform neurofibroma.
Yang L, Tan X, Bai HX, Huang Y, Wojcik J, Song S. Yang L, et al. Neurol India. 2018 Sep-Oct;66(5):1521-1522. doi: 10.4103/0028-3886.241333. Neurol India. 2018. PMID: 30233045 Free article. No abstract available.
Challenging Management of Plexiform Schwannoma and Plexiform Neurofibroma.
Nicoli TK, Saat R, Tarkkanen J, Kinnunen I, Mäkitie AA, Jero J. Nicoli TK, et al. J Craniofac Surg. 2022 May 1;33(3):803-808. doi: 10.1097/SCS.0000000000008381. Epub 2021 Dec 2. J Craniofac Surg. 2022. PMID: 34855632
Two plexiform schwannomas and 6 plexiform neurofibromas were identified. Five of the 6 plexiform neurofibromas were managed operatively. All patients with a surgically managed plexiform neurofibroma underwent multiple operations. Sclerotherapy a …
Two plexiform schwannomas and 6 plexiform neurofibromas were identified. Five of the 6 plexiform neurofibromas were man …
Plexiform neurofibroma genesis: questions of Nf1 gene dose and hyperactive mast cells.
Staser K, Yang FC, Clapp DW. Staser K, et al. Curr Opin Hematol. 2010 Jul;17(4):287-93. doi: 10.1097/MOH.0b013e328339511b. Curr Opin Hematol. 2010. PMID: 20571392 Free PMC article. Review.
Here, we discuss the importance of Nf1 gene dosage, delineate hematopoietic contributions to the plexiform neurofibroma microenvironment, and highlight applications to human treatment. ...Using these findings, clinicians have medically treated a patient with a debil …
Here, we discuss the importance of Nf1 gene dosage, delineate hematopoietic contributions to the plexiform neurofibroma microe …
Giant Perineal Plexiform Neurofibroma in an 8-Year-Old African Male.
Arredondo Montero J, Bronte Anaut M, Bardají Pascual C. Arredondo Montero J, et al. Fetal Pediatr Pathol. 2023 Feb;42(1):77-82. doi: 10.1080/15513815.2022.2045404. Epub 2022 Mar 2. Fetal Pediatr Pathol. 2023. PMID: 35234555
The perineal presentation of plexiform neurofibroma is exceptional, with only two cases reported to date. We present an 8-year-old African male with a large perineal tumor of years of evolution. ...Histopathological study of the specimen revealed a plexiform
The perineal presentation of plexiform neurofibroma is exceptional, with only two cases reported to date. We present an 8-year …
1,571 results