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Page 1
Medicinal Chemistry Approaches to Heart Regeneration.
Schade D, Plowright AT. Schade D, et al. Among authors: plowright at. J Med Chem. 2015 Dec 24;58(24):9451-79. doi: 10.1021/acs.jmedchem.5b00446. Epub 2015 Sep 3. J Med Chem. 2015. PMID: 26288266 Review.
High-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targets.
Woo LA, Tkachenko S, Ding M, Plowright AT, Engkvist O, Andersson H, Drowley L, Barrett I, Firth M, Akerblad P, Wolf MJ, Bekiranov S, Brautigan DL, Wang QD, Saucerman JJ. Woo LA, et al. Among authors: plowright at. J Mol Cell Cardiol. 2019 Feb;127:204-214. doi: 10.1016/j.yjmcc.2018.12.015. Epub 2018 Dec 28. J Mol Cell Cardiol. 2019. PMID: 30597148 Free PMC article.
Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach.
Drowley L, McPheat J, Nordqvist A, Peel S, Karlsson U, Martinsson S, Müllers E, Dellsén A, Knight S, Barrett I, Sánchez J, Magnusson B, Greber B, Wang QD, Plowright AT. Drowley L, et al. Among authors: plowright at. Stem Cells Transl Med. 2020 Jan;9(1):47-60. doi: 10.1002/sctm.19-0069. Epub 2019 Sep 11. Stem Cells Transl Med. 2020. PMID: 31508905 Free PMC article.
Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells in Phenotypic Screening: A Transforming Growth Factor-β Type 1 Receptor Kinase Inhibitor Induces Efficient Cardiac Differentiation.
Drowley L, Koonce C, Peel S, Jonebring A, Plowright AT, Kattman SJ, Andersson H, Anson B, Swanson BJ, Wang QD, Brolen G. Drowley L, et al. Among authors: plowright at. Stem Cells Transl Med. 2016 Feb;5(2):164-74. doi: 10.5966/sctm.2015-0114. Epub 2015 Dec 18. Stem Cells Transl Med. 2016. PMID: 26683871 Free PMC article.
Comparative transcriptomic analysis identifies genes differentially expressed in human epicardial progenitors and hiPSC-derived cardiac progenitors.
Synnergren J, Drowley L, Plowright AT, Brolén G, Goumans MJ, Gittenberger-de Groot AC, Sartipy P, Wang QD. Synnergren J, et al. Among authors: plowright at. Physiol Genomics. 2016 Nov 1;48(11):771-784. doi: 10.1152/physiolgenomics.00064.2016. Epub 2016 Sep 2. Physiol Genomics. 2016. PMID: 27591124 Free article.
Phenotypic Screen for Cardiac Regeneration Identifies Molecules with Differential Activity in Human Epicardium-Derived Cells versus Cardiac Fibroblasts.
Paunovic AI, Drowley L, Nordqvist A, Ericson E, Mouchet E, Jonebring A, Grönberg G, Kvist AJ, Engkvist O, Brown MR, Gedda K, Goumans MJ, Wang QD, Plowright AT. Paunovic AI, et al. Among authors: plowright at. ACS Chem Biol. 2017 Jan 20;12(1):132-141. doi: 10.1021/acschembio.6b00683. Epub 2016 Nov 30. ACS Chem Biol. 2017. PMID: 28103692
Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest.
Mills RJ, Titmarsh DM, Koenig X, Parker BL, Ryall JG, Quaife-Ryan GA, Voges HK, Hodson MP, Ferguson C, Drowley L, Plowright AT, Needham EJ, Wang QD, Gregorevic P, Xin M, Thomas WG, Parton RG, Nielsen LK, Launikonis BS, James DE, Elliott DA, Porrello ER, Hudson JE. Mills RJ, et al. Among authors: plowright at. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8372-E8381. doi: 10.1073/pnas.1707316114. Epub 2017 Sep 15. Proc Natl Acad Sci U S A. 2017. PMID: 28916735 Free PMC article.
46 results