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Could an endoneurial endothelial crosstalk between Wnt/β-catenin and Sonic Hedgehog pathways underlie the early disruption of the infra-orbital blood-nerve barrier following chronic constriction injury?
Moreau N, Mauborgne A, Couraud PO, Romero IA, Weksler BB, Villanueva L, Pohl M, Boucher Y. Moreau N, et al. Among authors: Pohl M. Mol Pain. 2017 Jan-Dec;13:1744806917727625. doi: 10.1177/1744806917727625. Mol Pain. 2017. PMID: 28814148 Free PMC article.
CCL2 released from neuronal synaptic vesicles in the spinal cord is a major mediator of local inflammation and pain after peripheral nerve injury.
Van Steenwinckel J, Reaux-Le Goazigo A, Pommier B, Mauborgne A, Dansereau MA, Kitabgi P, Sarret P, Pohl M, Mélik Parsadaniantz S. Van Steenwinckel J, et al. Among authors: Pohl M. J Neurosci. 2011 Apr 13;31(15):5865-75. doi: 10.1523/JNEUROSCI.5986-10.2011. J Neurosci. 2011. PMID: 21490228 Free PMC article.
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