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Page 1
A common phosphotyrosine signature for the Bcr-Abl kinase.
Goss VL, Lee KA, Moritz A, Nardone J, Spek EJ, MacNeill J, Rush J, Comb MJ, Polakiewicz RD. Goss VL, et al. Among authors: polakiewicz rd. Blood. 2006 Jun 15;107(12):4888-97. doi: 10.1182/blood-2005-08-3399. Epub 2006 Feb 23. Blood. 2006. PMID: 16497976 Free PMC article.
A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia.
Gu TL, Mercher T, Tyner JW, Goss VL, Walters DK, Cornejo MG, Reeves C, Popova L, Lee K, Heinrich MC, Rush J, Daibata M, Miyoshi I, Gilliland DG, Druker BJ, Polakiewicz RD. Gu TL, et al. Among authors: polakiewicz rd. Blood. 2007 Jul 1;110(1):323-33. doi: 10.1182/blood-2006-10-052282. Epub 2007 Mar 14. Blood. 2007. PMID: 17360941 Free PMC article.
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.
Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, Nardone J, Lee K, Reeves C, Li Y, Hu Y, Tan Z, Stokes M, Sullivan L, Mitchell J, Wetzel R, Macneill J, Ren JM, Yuan J, Bakalarski CE, Villen J, Kornhauser JM, Smith B, Li D, Zhou X, Gygi SP, Gu TL, Polakiewicz RD, Rush J, Comb MJ. Rikova K, et al. Among authors: polakiewicz rd. Cell. 2007 Dec 14;131(6):1190-203. doi: 10.1016/j.cell.2007.11.025. Cell. 2007. PMID: 18083107 Free article.
Signaling networks assembled by oncogenic EGFR and c-Met.
Guo A, Villén J, Kornhauser J, Lee KA, Stokes MP, Rikova K, Possemato A, Nardone J, Innocenti G, Wetzel R, Wang Y, MacNeill J, Mitchell J, Gygi SP, Rush J, Polakiewicz RD, Comb MJ. Guo A, et al. Among authors: polakiewicz rd. Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):692-7. doi: 10.1073/pnas.0707270105. Epub 2008 Jan 7. Proc Natl Acad Sci U S A. 2008. PMID: 18180459 Free PMC article.
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ. Rush J, et al. Among authors: polakiewicz rd. Nat Biotechnol. 2005 Jan;23(1):94-101. doi: 10.1038/nbt1046. Epub 2004 Dec 12. Nat Biotechnol. 2005. PMID: 15592455
Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib.
Griswold IJ, MacPartlin M, Bumm T, Goss VL, O'Hare T, Lee KA, Corbin AS, Stoffregen EP, Smith C, Johnson K, Moseson EM, Wood LJ, Polakiewicz RD, Druker BJ, Deininger MW. Griswold IJ, et al. Among authors: polakiewicz rd. Mol Cell Biol. 2006 Aug;26(16):6082-93. doi: 10.1128/MCB.02202-05. Mol Cell Biol. 2006. PMID: 16880519 Free PMC article.
Profiling of UV-induced ATM/ATR signaling pathways.
Stokes MP, Rush J, Macneill J, Ren JM, Sprott K, Nardone J, Yang V, Beausoleil SA, Gygi SP, Livingstone M, Zhang H, Polakiewicz RD, Comb MJ. Stokes MP, et al. Among authors: polakiewicz rd. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19855-60. doi: 10.1073/pnas.0707579104. Epub 2007 Dec 6. Proc Natl Acad Sci U S A. 2007. PMID: 18077418 Free PMC article.
The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL.
Boccalatte FE, Voena C, Riganti C, Bosia A, D'Amico L, Riera L, Cheng M, Ruggeri B, Jensen ON, Goss VL, Lee K, Nardone J, Rush J, Polakiewicz RD, Comb MJ, Chiarle R, Inghirami G. Boccalatte FE, et al. Among authors: polakiewicz rd. Blood. 2009 Mar 19;113(12):2776-90. doi: 10.1182/blood-2008-06-161018. Epub 2008 Oct 9. Blood. 2009. PMID: 18845790 Free PMC article.
Survey of activated FLT3 signaling in leukemia.
Gu TL, Nardone J, Wang Y, Loriaux M, Villén J, Beausoleil S, Tucker M, Kornhauser J, Ren J, MacNeill J, Gygi SP, Druker BJ, Heinrich MC, Rush J, Polakiewicz RD. Gu TL, et al. Among authors: polakiewicz rd. PLoS One. 2011 Apr 28;6(4):e19169. doi: 10.1371/journal.pone.0019169. PLoS One. 2011. PMID: 21552520 Free PMC article.
70 results