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Foxp3 occupancy and regulation of key target genes during T-cell stimulation.
Marson A, Kretschmer K, Frampton GM, Jacobsen ES, Polansky JK, MacIsaac KD, Levine SS, Fraenkel E, von Boehmer H, Young RA. Marson A, et al. Among authors: polansky jk. Nature. 2007 Feb 22;445(7130):931-5. doi: 10.1038/nature05478. Epub 2007 Jan 21. Nature. 2007. PMID: 17237765 Free PMC article.
Epigenetic control of the foxp3 locus in regulatory T cells.
Floess S, Freyer J, Siewert C, Baron U, Olek S, Polansky J, Schlawe K, Chang HD, Bopp T, Schmitt E, Klein-Hessling S, Serfling E, Hamann A, Huehn J. Floess S, et al. PLoS Biol. 2007 Feb;5(2):e38. doi: 10.1371/journal.pbio.0050038. PLoS Biol. 2007. PMID: 17298177 Free PMC article.
DNA methylation controls Foxp3 gene expression.
Polansky JK, Kretschmer K, Freyer J, Floess S, Garbe A, Baron U, Olek S, Hamann A, von Boehmer H, Huehn J. Polansky JK, et al. Eur J Immunol. 2008 Jun;38(6):1654-63. doi: 10.1002/eji.200838105. Eur J Immunol. 2008. PMID: 18493985
Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus.
Toker A, Engelbert D, Garg G, Polansky JK, Floess S, Miyao T, Baron U, Düber S, Geffers R, Giehr P, Schallenberg S, Kretschmer K, Olek S, Walter J, Weiss S, Hori S, Hamann A, Huehn J. Toker A, et al. Among authors: polansky jk. J Immunol. 2013 Apr 1;190(7):3180-8. doi: 10.4049/jimmunol.1203473. Epub 2013 Feb 18. J Immunol. 2013. PMID: 23420886
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