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96 results
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Notch in mammary gland development and breast cancer.
Politi K, Feirt N, Kitajewski J. Politi K, et al. Semin Cancer Biol. 2004 Oct;14(5):341-7. doi: 10.1016/j.semcancer.2004.04.013. Semin Cancer Biol. 2004. PMID: 15288259 Review.
Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice.
Klinakis A, Szabolcs M, Politi K, Kiaris H, Artavanis-Tsakonas S, Efstratiadis A. Klinakis A, et al. Among authors: politi k. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9262-7. doi: 10.1073/pnas.0603371103. Epub 2006 Jun 2. Proc Natl Acad Sci U S A. 2006. PMID: 16751266 Free PMC article.
'Designer' tumors in mice.
Politi K, Kljuic A, Szabolcs M, Fisher P, Ludwig T, Efstratiadis A. Politi K, et al. Oncogene. 2004 Feb 26;23(8):1558-65. doi: 10.1038/sj.onc.1207275. Oncogene. 2004. PMID: 14661057
Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium.
Kiaris H, Politi K, Grimm LM, Szabolcs M, Fisher P, Efstratiadis A, Artavanis-Tsakonas S. Kiaris H, et al. Among authors: politi k. Am J Pathol. 2004 Aug;165(2):695-705. doi: 10.1016/S0002-9440(10)63333-0. Am J Pathol. 2004. PMID: 15277242 Free PMC article.
Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor-Driven Lung Adenocarcinoma.
Maity TK, Venugopalan A, Linnoila I, Cultraro CM, Giannakou A, Nemati R, Zhang X, Webster JD, Ritt D, Ghosal S, Hoschuetzky H, Simpson RM, Biswas R, Politi K, Morrison DK, Varmus HE, Guha U. Maity TK, et al. Among authors: politi k. Cancer Discov. 2015 May;5(5):534-49. doi: 10.1158/2159-8290.CD-14-0750. Epub 2015 Mar 3. Cancer Discov. 2015. PMID: 25735773 Free PMC article.
ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas.
Song X, Fan PD, Bantikassegn A, Guha U, Threadgill DW, Varmus H, Politi K. Song X, et al. Among authors: politi k. Cancer Res. 2015 Mar 15;75(6):1035-45. doi: 10.1158/0008-5472.CAN-13-1625. Epub 2015 Jan 16. Cancer Res. 2015. PMID: 25596284 Free PMC article.
Erlotinib resistance in mouse models of epidermal growth factor receptor-induced lung adenocarcinoma.
Politi K, Fan PD, Shen R, Zakowski M, Varmus H. Politi K, et al. Dis Model Mech. 2010 Jan-Feb;3(1-2):111-9. doi: 10.1242/dmm.003681. Epub 2009 Dec 9. Dis Model Mech. 2010. PMID: 20007486 Free PMC article.
Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras.
Podsypanina K, Politi K, Beverly LJ, Varmus HE. Podsypanina K, et al. Among authors: politi k. Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5242-7. doi: 10.1073/pnas.0801197105. Epub 2008 Mar 20. Proc Natl Acad Sci U S A. 2008. PMID: 18356293 Free PMC article.
Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response.
Sangodkar J, Dhawan NS, Melville H, Singh VJ, Yuan E, Rana H, Izadmehr S, Farrington C, Mazhar S, Katz S, Albano T, Arnovitz P, Okrent R, Ohlmeyer M, Galsky M, Burstein D, Zhang D, Politi K, Difeo A, Narla G. Sangodkar J, et al. Among authors: politi k. J Clin Invest. 2012 Jul;122(7):2637-51. doi: 10.1172/JCI62058. Epub 2012 Jun 1. J Clin Invest. 2012. PMID: 22653055 Free PMC article.
Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer.
Gettinger S, Choi J, Hastings K, Truini A, Datar I, Sowell R, Wurtz A, Dong W, Cai G, Melnick MA, Du VY, Schlessinger J, Goldberg SB, Chiang A, Sanmamed MF, Melero I, Agorreta J, Montuenga LM, Lifton R, Ferrone S, Kavathas P, Rimm DL, Kaech SM, Schalper K, Herbst RS, Politi K. Gettinger S, et al. Among authors: politi k. Cancer Discov. 2017 Dec;7(12):1420-1435. doi: 10.1158/2159-8290.CD-17-0593. Epub 2017 Oct 12. Cancer Discov. 2017. PMID: 29025772 Free PMC article.
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