Pollastri MP - Search Results

1

Identification of cinnabarinic acid as a novel endogenous aryl hydrocarbon receptor ligand that drives IL-22 production.

Lowe MM, Mold JE, Kanwar B, Huang Y, Louie A, Pollastri MP, Wang C, Patel G, Franks DG, Schlezinger J, Sherr DH, Silverstone AE, Hahn ME, McCune JM. Lowe MM, et al. Among authors: pollastri mp. PLoS One. 2014 Feb 3;9(2):e87877. doi: 10.1371/journal.pone.0087877. eCollection 2014. PLoS One. 2014. PMID: 24498387 Free PMC article.

2

Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 2. Tadalafil analogs.

Ochiana SO, Gustafson A, Bland ND, Wang C, Russo MJ, Campbell RK, Pollastri MP. Ochiana SO, et al. Among authors: pollastri mp. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2582-4. doi: 10.1016/j.bmcl.2012.01.118. Epub 2012 Feb 9. Bioorg Med Chem Lett. 2012. PMID: 22377518 Free PMC article.

3

Kinase scaffold repurposing for neglected disease drug discovery: discovery of an efficacious, lapatinib-derived lead compound for trypanosomiasis.

Patel G, Karver CE, Behera R, Guyett PJ, Sullenberger C, Edwards P, Roncal NE, Mensa-Wilmot K, Pollastri MP. Patel G, et al. Among authors: pollastri mp. J Med Chem. 2013 May 23;56(10):3820-32. doi: 10.1021/jm400349k. Epub 2013 May 3. J Med Chem. 2013. PMID: 23597080 Free PMC article.

4

Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery.

Patel G, Roncal NE, Lee PJ, Leed SE, Erath J, Rodriguez A, Sciotti RJ, Pollastri MP. Patel G, et al. Among authors: pollastri mp. Medchemcomm. 2014 May 1;5(5):655-658. doi: 10.1039/C4MD00045E. Medchemcomm. 2014. PMID: 24910766 Free PMC article.

5

In silico identification of an aryl hydrocarbon receptor antagonist with biological activity in vitro and in vivo.

Parks AJ, Pollastri MP, Hahn ME, Stanford EA, Novikov O, Franks DG, Haigh SE, Narasimhan S, Ashton TD, Hopper TG, Kozakov D, Beglov D, Vajda S, Schlezinger JJ, Sherr DH. Parks AJ, et al. Among authors: pollastri mp. Mol Pharmacol. 2014 Nov;86(5):593-608. doi: 10.1124/mol.114.093369. Epub 2014 Aug 26. Mol Pharmacol. 2014. PMID: 25159092 Free PMC article.

6

EVALUATION OF AROMATIC 6-SUBSTITUTED THIENOPYRIMIDINES AS SCAFFOLDS AGAINST PARASITES THAT CAUSE TRYPANOSOMIASIS, LEISHMANIASIS, AND MALARIA.

Woodring JL, Patel G, Erath J, Behera R, Lee PJ, Leed SE, Rodriguez A, Sciotti RJ, Mensa-Wilmot K, Pollastri MP. Woodring JL, et al. Among authors: pollastri mp. Medchemcomm. 2015 Feb;6(2):339-346. doi: 10.1039/C4MD00441H. Medchemcomm. 2015. PMID: 25685309 Free PMC article.

7

The Aryl Hydrocarbon Receptor is a Critical Regulator of Tissue Factor Stability and an Antithrombotic Target in Uremia.

Shivanna S, Kolandaivelu K, Shashar M, Belghasim M, Al-Rabadi L, Balcells M, Zhang A, Weinberg J, Francis J, Pollastri MP, Edelman ER, Sherr DH, Chitalia VC. Shivanna S, et al. Among authors: pollastri mp. J Am Soc Nephrol. 2016 Jan;27(1):189-201. doi: 10.1681/ASN.2014121241. Epub 2015 May 27. J Am Soc Nephrol. 2016. PMID: 26019318 Free PMC article.

8

Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 1. Sildenafil analogs.

Wang C, Ashton TD, Gustafson A, Bland ND, Ochiana SO, Campbell RK, Pollastri MP. Wang C, et al. Among authors: pollastri mp. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2579-81. doi: 10.1016/j.bmcl.2012.01.119. Epub 2012 Feb 9. Bioorg Med Chem Lett. 2012. PMID: 22370268 Free PMC article.

9

Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery.

Devine W, Woodring JL, Swaminathan U, Amata E, Patel G, Erath J, Roncal NE, Lee PJ, Leed SE, Rodriguez A, Mensa-Wilmot K, Sciotti RJ, Pollastri MP. Devine W, et al. Among authors: pollastri mp. J Med Chem. 2015 Jul 23;58(14):5522-37. doi: 10.1021/acs.jmedchem.5b00515. Epub 2015 Jul 8. J Med Chem. 2015. PMID: 26087257 Free PMC article.

10

Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation.

Woodring JL, Behera R, Sharma A, Wiedeman J, Patel G, Singh B, Guyett P, Amata E, Erath J, Roncal N, Penn E, Leed SE, Rodriguez A, Sciotti RJ, Mensa-Wilmot K, Pollastri MP. Woodring JL, et al. Among authors: pollastri mp. ACS Med Chem Lett. 2018 Sep 4;9(10):996-1001. doi: 10.1021/acsmedchemlett.8b00245. eCollection 2018 Oct 11. ACS Med Chem Lett. 2018. PMID: 30344906 Free PMC article.

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