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Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state.
Chaffer CL, Brueckmann I, Scheel C, Kaestli AJ, Wiggins PA, Rodrigues LO, Brooks M, Reinhardt F, Su Y, Polyak K, Arendt LM, Kuperwasser C, Bierie B, Weinberg RA. Chaffer CL, et al. Among authors: polyak k. Proc Natl Acad Sci U S A. 2011 May 10;108(19):7950-5. doi: 10.1073/pnas.1102454108. Epub 2011 Apr 15. Proc Natl Acad Sci U S A. 2011. PMID: 21498687 Free PMC article.
HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells.
Krop IE, Sgroi D, Porter DA, Lunetta KL, LeVangie R, Seth P, Kaelin CM, Rhei E, Bosenberg M, Schnitt S, Marks JR, Pagon Z, Belina D, Razumovic J, Polyak K. Krop IE, et al. Among authors: polyak k. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9796-801. doi: 10.1073/pnas.171138398. Epub 2001 Jul 31. Proc Natl Acad Sci U S A. 2001. PMID: 11481438 Free PMC article.
The epithelial-mesenchymal transition generates cells with properties of stem cells.
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA. Mani SA, et al. Among authors: polyak k. Cell. 2008 May 16;133(4):704-15. doi: 10.1016/j.cell.2008.03.027. Cell. 2008. PMID: 18485877 Free PMC article.
Cell type-specific DNA methylation patterns in the human breast.
Bloushtain-Qimron N, Yao J, Snyder EL, Shipitsin M, Campbell LL, Mani SA, Hu M, Chen H, Ustyansky V, Antosiewicz JE, Argani P, Halushka MK, Thomson JA, Pharoah P, Porgador A, Sukumar S, Parsons R, Richardson AL, Stampfer MR, Gelman RS, Nikolskaya T, Nikolsky Y, Polyak K. Bloushtain-Qimron N, et al. Among authors: polyak k. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):14076-81. doi: 10.1073/pnas.0805206105. Epub 2008 Sep 9. Proc Natl Acad Sci U S A. 2008. PMID: 18780791 Free PMC article.
Cancer stem cells: a model in the making.
Marotta LL, Polyak K. Marotta LL, et al. Among authors: polyak k. Curr Opin Genet Dev. 2009 Feb;19(1):44-50. doi: 10.1016/j.gde.2008.12.003. Epub 2009 Jan 21. Curr Opin Genet Dev. 2009. PMID: 19167210 Review.
Progress in breast cancer research.
Polyak K, Vogt PK. Polyak K, et al. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2715-7. doi: 10.1073/pnas.1201091109. Epub 2012 Feb 13. Proc Natl Acad Sci U S A. 2012. PMID: 22331869 Free PMC article. No abstract available.
The RasGAP gene, RASAL2, is a tumor and metastasis suppressor.
McLaughlin SK, Olsen SN, Dake B, De Raedt T, Lim E, Bronson RT, Beroukhim R, Polyak K, Brown M, Kuperwasser C, Cichowski K. McLaughlin SK, et al. Among authors: polyak k. Cancer Cell. 2013 Sep 9;24(3):365-78. doi: 10.1016/j.ccr.2013.08.004. Cancer Cell. 2013. PMID: 24029233 Free PMC article.
250 results