Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1995 1
1998 2
1999 1
2000 1
2002 1
2004 1
2005 1
2006 1
2007 3
2008 2
2009 1
2010 5
2011 3
2012 6
2013 4
2014 3
2015 7
2016 6
2017 6
2018 3
2019 5
2020 9
2021 8
2022 10
2023 1
Text availability
Article attribute
Article type
Publication date

Search Results

80 results
Results by year
Filters applied: . Clear all
Page 1
Poncirin ameliorates oxygen glucose deprivation/reperfusion injury in cortical neurons via inhibiting NOX4-mediated NLRP3 inflammasome activation.
Wang R, Li L, Wang B. Wang R, et al. Int Immunopharmacol. 2022 Jan;102:107210. doi: 10.1016/j.intimp.2020.107210. Epub 2021 Jul 12. Int Immunopharmacol. 2022. PMID: 34266770
Importantly, poncirin administration notably abolished OGD/R-induced upregulation of NADPH oxidase 4 (NOX4), and overexpression of NOX4 neutralized poncirin-mediated neuroprotection. In conclusion, poncirin protects cortical neurons from OGD/R injury via inhi …
Importantly, poncirin administration notably abolished OGD/R-induced upregulation of NADPH oxidase 4 (NOX4), and overexpression of NO …
Poncirin ameliorates cardiac ischemia-reperfusion injury by activating PI3K/AKT/PGC-1α signaling.
Li B, Chen T, Hu W, Wang Z, Wu J, Zhou Q, Li P. Li B, et al. Eur J Pharmacol. 2022 Feb 15;917:174759. doi: 10.1016/j.ejphar.2022.174759. Epub 2022 Jan 12. Eur J Pharmacol. 2022. PMID: 35032487
Similarly, systemic poncirin treatment significantly reduced cardiomyocyte apoptosis and infarct size in rat hearts. In addition, activity of the PI3K/AKT/PGC-1alpha pathway was significantly increased by poncirin pretreatment in both A/R and I/R injury models, whil …
Similarly, systemic poncirin treatment significantly reduced cardiomyocyte apoptosis and infarct size in rat hearts. In addition, act …
Poncirin downregulates ATP-binding cassette transporters to enhance cisplatin sensitivity in cisplatin-resistant osteosarcoma cells.
Zhao L, Zhang W, Zhang F. Zhao L, et al. Phytother Res. 2021 Jan;35(1):278-288. doi: 10.1002/ptr.6798. Epub 2020 Aug 11. Phytother Res. 2021. PMID: 32779800
Poncirin decreased the expression levels of MDR1, MRP1, and BCRP, and inhibited the PI3K/Akt signaling in OS cells. Rescue experiments suggested that activation of the PI3K/Akt signaling by 740Y-P abolished poncirin-induced expression reduction of MDR1, MRP1, and BC …
Poncirin decreased the expression levels of MDR1, MRP1, and BCRP, and inhibited the PI3K/Akt signaling in OS cells. Rescue experiment …
Poncirin, an orally active flavonoid exerts antidiabetic complications and improves glucose uptake activating PI3K/Akt signaling pathway in insulin resistant C2C12 cells with anti-glycation capacities.
Yousof Ali M, Zaib S, Mizanur Rahman M, Jannat S, Iqbal J, Kyu Park S, Seog Chang M. Yousof Ali M, et al. Bioorg Chem. 2020 Sep;102:104061. doi: 10.1016/j.bioorg.2020.104061. Epub 2020 Jun 30. Bioorg Chem. 2020. PMID: 32653611
Poncirin, a natural flavanone glycoside present abundantly in many citrus fruits, contains an extensive range of biological activities. ...Consequently, poncirin increased GLUT-4 expression level by activating the IRS-1/PI3K/Akt/GSK-3 signaling pathway. ...
Poncirin, a natural flavanone glycoside present abundantly in many citrus fruits, contains an extensive range of biological activitie …
Poncirin attenuates CCL4-induced liver injury through inhibition of oxidative stress and inflammatory cytokines in mice.
Ullah H, Khan A, Baig MW, Ullah N, Ahmed N, Tipu MK, Ali H, Khan S. Ullah H, et al. BMC Complement Med Ther. 2020 Apr 19;20(1):115. doi: 10.1186/s12906-020-02906-7. BMC Complement Med Ther. 2020. PMID: 32307011 Free PMC article.
The poncirin have been reported for various anti-inflammatory, analgesic activity etc. ...Furthermore, the poncirin treatment also evidently decreased the inflammatory mediators. ...
The poncirin have been reported for various anti-inflammatory, analgesic activity etc. ...Furthermore, the poncirin treatment …
Poncirin Inhibits Osteoclast Differentiation and Bone Loss through Down-Regulation of NFATc1 In Vitro and In Vivo.
Chun KH, Jin HC, Kang KS, Chang TS, Hwang GS. Chun KH, et al. Biomol Ther (Seoul). 2020 Jul 1;28(4):337-343. doi: 10.4062/biomolther.2018.216. Biomol Ther (Seoul). 2020. PMID: 31500404 Free PMC article.
Evaluating the micro-CT of femurs revealed that bone erosion in poncirin treated mice was markedly attenuated. Our results indicate that poncirin exerts anti-osteoclastic effects in vitro and in vivo by suppressing osteoclast differentiation. We believe that ponc …
Evaluating the micro-CT of femurs revealed that bone erosion in poncirin treated mice was markedly attenuated. Our results indicate t …
Therapeutic Potential of Poncirin Against Numerous Human Health Complications: Medicinal Uses and Therapeutic Benefit of an Active Principle of Citrus Species.
Patel DK. Patel DK. Endocr Metab Immune Disord Drug Targets. 2021;21(11):1974-1981. doi: 10.2174/1871530321666210108122924. Endocr Metab Immune Disord Drug Targets. 2021. PMID: 33423654
Detailed pharmacological activities of poncirin were also investigated in the present investigation to reveal the medicinal properties of poncirin in medicine and other allied health sectors. ...From the analysis of the presented scientific information of ponciri …
Detailed pharmacological activities of poncirin were also investigated in the present investigation to reveal the medicinal propertie …
Poncirin promotes osteoblast differentiation but inhibits adipocyte differentiation in mesenchymal stem cells.
Yoon HY, Yun SI, Kim BY, Jin Q, Woo ER, Jeong SY, Chung YS. Yoon HY, et al. Eur J Pharmacol. 2011 Aug 16;664(1-3):54-9. doi: 10.1016/j.ejphar.2011.04.047. Epub 2011 May 1. Eur J Pharmacol. 2011. PMID: 21550337
In this study, the effects of poncirin on the differentiation of mesenchymal stem cells were investigated. ...Poncirin increased mineral nodule formation in primary bone marrow mesenchymal stem cells. ...
In this study, the effects of poncirin on the differentiation of mesenchymal stem cells were investigated. ...Poncirin increas …
Poncirin and its metabolite ponciretin attenuate colitis in mice by inhibiting LPS binding on TLR4 of macrophages and correcting Th17/Treg imbalance.
Kang GD, Kim DH. Kang GD, et al. J Ethnopharmacol. 2016 Aug 2;189:175-85. doi: 10.1016/j.jep.2016.05.044. Epub 2016 May 17. J Ethnopharmacol. 2016. PMID: 27224242
AIM OF THE STUDY: To examine anti-colitic effects of poncirin and ponciretin, a metabolite of poncirin by gut microbiota. ...The ant-inflammatory effect of ponciretin was superior to that of poncirin. CONCLUSION: Orally administered poncirin is metabol …
AIM OF THE STUDY: To examine anti-colitic effects of poncirin and ponciretin, a metabolite of poncirin by gut microbiota. ...T …
Poncirin prevents bone loss in glucocorticoid-induced osteoporosis in vivo and in vitro.
Yoon HY, Won YY, Chung YS. Yoon HY, et al. J Bone Miner Metab. 2012 Sep;30(5):509-16. doi: 10.1007/s00774-012-0350-8. Epub 2012 Mar 13. J Bone Miner Metab. 2012. PMID: 22407507
Poncirin, a flavonoid isolated from the fruit of Poncirus trifoliata, possesses anti-bacterial and anti-inflammatory activities. However, the action of poncirin in bone biology is unclear. In this study, the in vivo and in vitro effects of poncirin in a gluco …
Poncirin, a flavonoid isolated from the fruit of Poncirus trifoliata, possesses anti-bacterial and anti-inflammatory activities. Howe …
80 results