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Increased expression of the transcription factors CCAAT-enhancer binding protein-beta (C/EBBeta) and C/EBzeta (CHOP) correlate with invasiveness of human colorectal cancer.
Rask K, Thörn M, Pontén F, Kraaz W, Sundfeldt K, Hedin L, Enerbäck S. Rask K, et al. Int J Cancer. 2000 May 1;86(3):337-43. doi: 10.1002/(sici)1097-0215(20000501)86:3<337::aid-ijc6>3.0.co;2-3. Int J Cancer. 2000. PMID: 10760820
In situ identification of genes regulated specifically in fibroblasts of human basal cell carcinoma.
Micke P, Kappert K, Ohshima M, Sundquist C, Scheidl S, Lindahl P, Heldin CH, Botling J, Ponten F, Ostman A. Micke P, et al. J Invest Dermatol. 2007 Jun;127(6):1516-23. doi: 10.1038/sj.jid.5700714. Epub 2007 Feb 1. J Invest Dermatol. 2007. PMID: 17273163
HMG-CoA reductase expression in breast cancer is associated with a less aggressive phenotype and influenced by anthropometric factors.
Borgquist S, Djerbi S, Pontén F, Anagnostaki L, Goldman M, Gaber A, Manjer J, Landberg G, Jirström K. Borgquist S, et al. Int J Cancer. 2008 Sep 1;123(5):1146-53. doi: 10.1002/ijc.23597. Int J Cancer. 2008. PMID: 18528862
Immunohistochemical detection of tyrosine phosphatase SHP-1 predicts outcome after radical prostatectomy for localized prostate cancer.
Tassidis H, Brokken LJ, Jirström K, Ehrnström R, Pontén F, Ulmert D, Bjartell A, Härkönen P, Wingren AG. Tassidis H, et al. Int J Cancer. 2010 May 15;126(10):2296-307. doi: 10.1002/ijc.24917. Int J Cancer. 2010. PMID: 19795453
Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer.
Ehlén A, Brennan DJ, Nodin B, O'Connor DP, Eberhard J, Alvarado-Kristensson M, Jeffrey IB, Manjer J, Brändstedt J, Uhlén M, Pontén F, Jirström K. Ehlén A, et al. J Transl Med. 2010 Aug 20;8:78. doi: 10.1186/1479-5876-8-78. J Transl Med. 2010. PMID: 20727170 Free PMC article.
Increased expression of heparanase in symptomatic carotid atherosclerosis.
Osterholm C, Folkersen L, Lengquist M, Pontén F, Renné T, Li J, Hedin U. Osterholm C, et al. Atherosclerosis. 2013 Jan;226(1):67-73. doi: 10.1016/j.atherosclerosis.2012.09.030. Epub 2012 Oct 23. Atherosclerosis. 2013. PMID: 23137827
Novel signatures of cancer-associated fibroblasts.
Bozóky B, Savchenko A, Csermely P, Korcsmáros T, Dúl Z, Pontén F, Székely L, Klein G. Bozóky B, et al. Int J Cancer. 2013 Jul 15;133(2):286-93. doi: 10.1002/ijc.28035. Epub 2013 Feb 12. Int J Cancer. 2013. PMID: 23319410
Estrogen receptor β expression induces changes in the microRNA pool in human colon cancer cells.
Edvardsson K, Nguyen-Vu T, Kalasekar SM, Pontén F, Gustafsson JÅ, Williams C. Edvardsson K, et al. Carcinogenesis. 2013 Jul;34(7):1431-41. doi: 10.1093/carcin/bgt067. Epub 2013 Feb 22. Carcinogenesis. 2013. PMID: 23436804
CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer.
Cepeda D, Ng HF, Sharifi HR, Mahmoudi S, Cerrato VS, Fredlund E, Magnusson K, Nilsson H, Malyukova A, Rantala J, Klevebring D, Viñals F, Bhaskaran N, Zakaria SM, Rahmanto AS, Grotegut S, Nielsen ML, Szigyarto CA, Sun D, Lerner M, Navani S, Widschwendter M, Uhlén M, Jirström K, Pontén F, Wohlschlegel J, Grandér D, Spruck C, Larsson LG, Sangfelt O. Cepeda D, et al. EMBO Mol Med. 2013 Jul;5(7):1067-86. doi: 10.1002/emmm.201202341. Epub 2013 Jun 14. EMBO Mol Med. 2013. PMID: 23776131 Free PMC article.
SCF (Skp1/Cul1/F-box) ubiquitin ligases act as master regulators of cellular homeostasis by targeting key proteins for ubiquitylation. Here, we identified a hitherto uncharacterized F-box protein, FBXO28 that controls MYC-dependent transcription by non-proteolytic u …
SCF (Skp1/Cul1/F-box) ubiquitin ligases act as master regulators of cellular homeostasis by targeting key proteins for ubiquitylation …
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