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CD44: from adhesion molecules to signalling regulators.
Ponta H, Sherman L, Herrlich PA. Ponta H, et al. Nat Rev Mol Cell Biol. 2003 Jan;4(1):33-45. doi: 10.1038/nrm1004. Nat Rev Mol Cell Biol. 2003. PMID: 12511867 Review.
Hepatocyte growth factor-induced Ras activation requires ERM proteins linked to both CD44v6 and F-actin.
Orian-Rousseau V, Morrison H, Matzke A, Kastilan T, Pace G, Herrlich P, Ponta H. Orian-Rousseau V, et al. Among authors: ponta h. Mol Biol Cell. 2007 Jan;18(1):76-83. doi: 10.1091/mbc.e06-08-0674. Epub 2006 Oct 25. Mol Biol Cell. 2007. PMID: 17065554 Free PMC article.
Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling.
Matzke-Ogi A, Jannasch K, Shatirishvili M, Fuchs B, Chiblak S, Morton J, Tawk B, Lindner T, Sansom O, Alves F, Warth A, Schwager C, Mier W, Kleeff J, Ponta H, Abdollahi A, Orian-Rousseau V. Matzke-Ogi A, et al. Among authors: ponta h. Gastroenterology. 2016 Feb;150(2):513-25.e10. doi: 10.1053/j.gastro.2015.10.020. Epub 2015 Oct 24. Gastroenterology. 2016. PMID: 26597578
c-Met recruits ICAM-1 as a coreceptor to compensate for the loss of CD44 in Cd44 null mice.
Olaku V, Matzke A, Mitchell C, Hasenauer S, Sakkaravarthi A, Pace G, Ponta H, Orian-Rousseau V. Olaku V, et al. Among authors: ponta h. Mol Biol Cell. 2011 Aug 1;22(15):2777-86. doi: 10.1091/mbc.E11-02-0134. Epub 2011 Jun 16. Mol Biol Cell. 2011. PMID: 21680714 Free PMC article.
A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis.
Tremmel M, Matzke A, Albrecht I, Laib AM, Olaku V, Ballmer-Hofer K, Christofori G, Héroult M, Augustin HG, Ponta H, Orian-Rousseau V. Tremmel M, et al. Among authors: ponta h. Blood. 2009 Dec 10;114(25):5236-44. doi: 10.1182/blood-2009-04-219204. Blood. 2009. PMID: 19773544
A five-amino-acid peptide blocks Met- and Ron-dependent cell migration.
Matzke A, Herrlich P, Ponta H, Orian-Rousseau V. Matzke A, et al. Among authors: ponta h. Cancer Res. 2005 Jul 15;65(14):6105-10. doi: 10.1158/0008-5472.CAN-05-0207. Cancer Res. 2005. PMID: 16024611 Free article.
CD44 variant-specific antibodies trigger hemopoiesis by selective release of cytokines from bone marrow macrophages.
Khaldoyanidi S, Karakhanova S, Sleeman J, Herrlich P, Ponta H. Khaldoyanidi S, et al. Among authors: ponta h. Blood. 2002 Jun 1;99(11):3955-61. doi: 10.1182/blood.v99.11.3955. Blood. 2002. PMID: 12010794
CD44 is required for two consecutive steps in HGF/c-Met signaling.
Orian-Rousseau V, Chen L, Sleeman JP, Herrlich P, Ponta H. Orian-Rousseau V, et al. Among authors: ponta h. Genes Dev. 2002 Dec 1;16(23):3074-86. doi: 10.1101/gad.242602. Genes Dev. 2002. PMID: 12464636 Free PMC article.
The CD44 protein family: roles in embryogenesis and tumor progression.
Ponta H, Herrlich P. Ponta H, et al. Front Biosci. 1998 Jul 1;3:d650-656. doi: 10.2741/a309. Front Biosci. 1998. PMID: 28481212
Haploinsufficiency of c-Met in cd44-/- mice identifies a collaboration of CD44 and c-Met in vivo.
Matzke A, Sargsyan V, Holtmann B, Aramuni G, Asan E, Sendtner M, Pace G, Howells N, Zhang W, Ponta H, Orian-Rousseau V. Matzke A, et al. Among authors: ponta h. Mol Cell Biol. 2007 Dec;27(24):8797-806. doi: 10.1128/MCB.01355-07. Epub 2007 Oct 8. Mol Cell Biol. 2007. PMID: 17923692 Free PMC article.
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