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Optimization of 2-(1H-imidazo-2-yl)piperazines series of Trypanosoma brucei growth inhibitors as potential treatment for the second stage of HAT.
Ciammaichella A, Ferrigno F, Basta A, D'Amico M, Biancofiore I, Nardi V, Ponzi S, Graziani R, Gennari N, Vittoria Orsale M, Fini I, Paonessa G, Summa V, Harper S, Ontoria JM. Ciammaichella A, et al. Among authors: ponzi s. Bioorg Med Chem Lett. 2020 Jun 15;30(12):127207. doi: 10.1016/j.bmcl.2020.127207. Epub 2020 Apr 21. Bioorg Med Chem Lett. 2020. PMID: 32354566
Discovery of 4-((1-(1H-imidazol-2-yl)alkoxy)methyl)pyridines as a new class of Trypanosoma cruzi growth inhibitors.
Ponzi S, Bresciani A, Kaiser M, Nardi V, Nizi E, Ontoria JM, Pace P, Paonessa G, Summa V, Harper S. Ponzi S, et al. Bioorg Med Chem Lett. 2020 Apr 15;30(8):127052. doi: 10.1016/j.bmcl.2020.127052. Epub 2020 Feb 22. Bioorg Med Chem Lett. 2020. PMID: 32113841
Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides.
Bresciani A, Ontoria JM, Biancofiore I, Cellucci A, Ciammaichella A, Di Marco A, Ferrigno F, Francone A, Malancona S, Monteagudo E, Nizi E, Pace P, Ponzi S, Rossetti I, Veneziano M, Summa V, Harper S. Bresciani A, et al. Among authors: ponzi s. ACS Med Chem Lett. 2018 Nov 27;10(4):481-486. doi: 10.1021/acsmedchemlett.8b00517. eCollection 2019 Apr 11. ACS Med Chem Lett. 2018. PMID: 30996783 Free PMC article.
Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitro.
Ferrigno F, Biancofiore I, Malancona S, Ponzi S, Paonessa G, Graziani R, Bresciani A, Gennari N, Di Marco A, Kaiser M, Summa V, Harper S, Ontoria JM. Ferrigno F, et al. Among authors: ponzi s. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3689-3692. doi: 10.1016/j.bmcl.2018.10.028. Epub 2018 Oct 22. Bioorg Med Chem Lett. 2018. PMID: 30482621
Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs.
Ontoria JM, Paonessa G, Ponzi S, Ferrigno F, Nizi E, Biancofiore I, Malancona S, Graziani R, Roberts D, Willis P, Bresciani A, Gennari N, Cecchetti O, Monteagudo E, Orsale MV, Veneziano M, Di Marco A, Cellucci A, Laufer R, Altamura S, Summa V, Harper S. Ontoria JM, et al. Among authors: ponzi s. ACS Med Chem Lett. 2016 Mar 5;7(5):454-9. doi: 10.1021/acsmedchemlett.5b00468. eCollection 2016 May 12. ACS Med Chem Lett. 2016. PMID: 27190592 Free PMC article.
Preoperative embolization of carotid chemodectoma: a technical challenge that can be customized according to angioarchitecture. Illustrative cases.
Faragò G, Castellani C, Ponzi S, Jankovic C, Saginario V, Berardi C, Pollo B, Ciceri EF. Faragò G, et al. Among authors: ponzi s. Neuroradiol J. 2013 Dec;26(6):678-82. doi: 10.1177/197140091302600611. Epub 2013 Dec 18. Neuroradiol J. 2013. PMID: 24355187 Free PMC article.
The windowed sound therapy: a new empirical approach for an effectiv personalized treatment of tinnitus.
Lugli M, Romani R, Ponzi S, Bacciu S, Parmigiani S. Lugli M, et al. Among authors: ponzi s. Int Tinnitus J. 2009;15(1):51-61. Int Tinnitus J. 2009. PMID: 19842347 Clinical Trial.
Optimization of thienopyrrole-based finger-loop inhibitors of the hepatitis C virus NS5B polymerase.
Martin Hernando JI, Ontoria JM, Malancona S, Attenni B, Fiore F, Bonelli F, Koch U, Di Marco S, Colarusso S, Ponzi S, Gennari N, Vignetti SE, Del Rosario Rico Ferreira M, Habermann J, Rowley M, Narjes F. Martin Hernando JI, et al. Among authors: ponzi s. ChemMedChem. 2009 Oct;4(10):1695-713. doi: 10.1002/cmdc.200900184. ChemMedChem. 2009. PMID: 19672916
Identification of thieno[3,2-b]pyrroles as allosteric inhibitors of hepatitis C virus NS5B polymerase.
Ontoria JM, Martìn Hernando JI, Malancona S, Attenni B, Stansfield I, Conte I, Ercolani C, Habermann J, Ponzi S, Di Filippo M, Koch U, Rowley M, Narjes F. Ontoria JM, et al. Among authors: ponzi s. Bioorg Med Chem Lett. 2006 Aug 1;16(15):4026-30. doi: 10.1016/j.bmcl.2006.05.012. Epub 2006 May 22. Bioorg Med Chem Lett. 2006. PMID: 16714108
Active site inhibitors of HCV NS5B polymerase. The development and pharmacophore of 2-thienyl-5,6-dihydroxypyrimidine-4-carboxylic acid.
Stansfield I, Avolio S, Colarusso S, Gennari N, Narjes F, Pacini B, Ponzi S, Harper S. Stansfield I, et al. Among authors: ponzi s. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5085-8. doi: 10.1016/j.bmcl.2004.07.075. Bioorg Med Chem Lett. 2004. PMID: 15380204
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