Poole AR - Search Results

1

Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3).

Leco KJ, Waterhouse P, Sanchez OH, Gowing KL, Poole AR, Wakeham A, Mak TW, Khokha R. Leco KJ, et al. Among authors: poole ar. J Clin Invest. 2001 Sep;108(6):817-29. doi: 10.1172/JCI12067. J Clin Invest. 2001. PMID: 11560951 Free PMC article.

2

Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage.

Billinghurst RC, Dahlberg L, Ionescu M, Reiner A, Bourne R, Rorabeck C, Mitchell P, Hambor J, Diekmann O, Tschesche H, Chen J, Van Wart H, Poole AR. Billinghurst RC, et al. Among authors: poole ar. J Clin Invest. 1997 Apr 1;99(7):1534-45. doi: 10.1172/JCI119316. J Clin Invest. 1997. PMID: 9119997 Free PMC article.

3

Immunohistochemical detection and immunochemical analysis of type II collagen degradation in human normal, rheumatoid, and osteoarthritic articular cartilages and in explants of bovine articular cartilage cultured with interleukin 1.

Dodge GR, Poole AR. Dodge GR, et al. Among authors: poole ar. J Clin Invest. 1989 Feb;83(2):647-61. doi: 10.1172/JCI113929. J Clin Invest. 1989. PMID: 2783591 Free PMC article.

4

Changes in cartilage metabolism in arthritis are reflected by altered serum and synovial fluid levels of the cartilage proteoglycan aggrecan. Implications for pathogenesis.

Poole AR, Ionescu M, Swan A, Dieppe PA. Poole AR, et al. J Clin Invest. 1994 Jul;94(1):25-33. doi: 10.1172/JCI117314. J Clin Invest. 1994. PMID: 7518830 Free PMC article.

5

Immunity to the G1 globular domain of the cartilage proteoglycan aggrecan can induce inflammatory erosive polyarthritis and spondylitis in BALB/c mice but immunity to G1 is inhibited by covalently bound keratan sulfate in vitro and in vivo.

Leroux JY, Guerassimov A, Cartman A, Delaunay N, Webber C, Rosenberg LC, Banerjee S, Poole AR. Leroux JY, et al. Among authors: poole ar. J Clin Invest. 1996 Feb 1;97(3):621-32. doi: 10.1172/JCI118458. J Clin Invest. 1996. PMID: 8609216 Free PMC article.

6

Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration.

Hollander AP, Pidoux I, Reiner A, Rorabeck C, Bourne R, Poole AR. Hollander AP, et al. Among authors: poole ar. J Clin Invest. 1995 Dec;96(6):2859-69. doi: 10.1172/JCI118357. J Clin Invest. 1995. PMID: 8675657 Free PMC article.

7

Arthritis induced by proteoglycan aggrecan G1 domain in BALB/c mice. Evidence for t cell involvement and the immunosuppressive influence of keratan sulfate on recognition of t and b cell epitopes.

Zhang Y, Guerassimov A, Leroux JY, Cartman A, Webber C, Lalic R, de Miguel E, Rosenberg LC, Poole AR. Zhang Y, et al. Among authors: poole ar. J Clin Invest. 1998 Apr 15;101(8):1678-86. doi: 10.1172/JCI1666. J Clin Invest. 1998. PMID: 9541498 Free PMC article.

8

Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice.

Neuhold LA, Killar L, Zhao W, Sung ML, Warner L, Kulik J, Turner J, Wu W, Billinghurst C, Meijers T, Poole AR, Babij P, DeGennaro LJ. Neuhold LA, et al. Among authors: poole ar. J Clin Invest. 2001 Jan;107(1):35-44. doi: 10.1172/JCI10564. J Clin Invest. 2001. PMID: 11134178 Free PMC article.

9

Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis. Evidence for molecular heterogeneity and extensive molecular changes in disease.

Rizkalla G, Reiner A, Bogoch E, Poole AR. Rizkalla G, et al. Among authors: poole ar. J Clin Invest. 1992 Dec;90(6):2268-77. doi: 10.1172/JCI116113. J Clin Invest. 1992. PMID: 1281828 Free PMC article.

10

Kniest dysplasia is characterized by an apparent abnormal processing of the C-propeptide of type II cartilage collagen resulting in imperfect fibril assembly.

Poole AR, Pidoux I, Reiner A, Rosenberg L, Hollister D, Murray L, Rimoin D. Poole AR, et al. J Clin Invest. 1988 Feb;81(2):579-89. doi: 10.1172/JCI113356. J Clin Invest. 1988. PMID: 3276736 Free PMC article.

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