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2002 1
2003 1
2004 1
2005 1
2006 1
2007 1
2008 3
2009 4
2010 3
2011 2
2012 5
2013 5
2014 4
2015 6
2016 3
2017 3
2018 5
2019 7
2020 11
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2022 10
2023 11
2024 7

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Page 1
Precise correction of a spectrum of β-thalassemia mutations in coding and non-coding regions by base editors.
Prasad K, Devaraju N, George A, Ravi NS, Paul J, Mahalingam G, Rajendiran V, Panigrahi L, Venkatesan V, Lakhotiya K, Periyasami Y, Pai AA, Nakamura Y, Kurita R, Balasubramanian P, Thangavel S, Velayudhan SR, Newby GA, Marepally S, Srivastava A, Mohankumar KM. Prasad K, et al. Among authors: balasubramanian p. Mol Ther Nucleic Acids. 2024 May 3;35(2):102205. doi: 10.1016/j.omtn.2024.102205. eCollection 2024 Jun 11. Mol Ther Nucleic Acids. 2024. PMID: 38817682 Free PMC article.
Efficient deletion of microRNAs using CRISPR/Cas9 with dual guide RNAs.
Ijee S, Chambayil K, Chaudhury AD, Bagchi A, Modak K, Das S, Benjamin ESB, Rani S, Paul DZ, Nath A, Roy D, Palani D, Priyanka S, Ravichandran R, Kumary BK, Sivamani Y, S V, Babu D, Nakamura Y, Thamodaran V, Balasubramanian P, Velayudhan SR. Ijee S, et al. Among authors: balasubramanian p. Front Mol Biosci. 2024 Apr 2;10:1295507. doi: 10.3389/fmolb.2023.1295507. eCollection 2023. Front Mol Biosci. 2024. PMID: 38628442 Free PMC article.
Cystatin F a potential diagnostic biomarker in acute promyelocytic leukemia.
Palani HK, Ganesan S, Balasundaram N, Venkatraman A, Kulkarni U, Korula A, Nair SC, Mani T, Balasubramanian P, Abraham A, Puttamallesh VN, Gowda H, Mathews V. Palani HK, et al. Among authors: balasubramanian p. Ann Hematol. 2024 Jun;103(6):2181-2183. doi: 10.1007/s00277-024-05673-4. Epub 2024 Mar 1. Ann Hematol. 2024. PMID: 38427058 Free PMC article. No abstract available.
Immortalised chronic myeloid leukemia (CML) derived mesenchymal stromal cells (MSCs) line retains the immunomodulatory and chemoprotective properties of CML patient-derived MSCs.
Benjamin ESB, Vinod E, Illangeswaran RSS, Rajamani BM, Vidhyadharan RT, Bagchi A, Maity A, Mohan A, Parasuraman G, Amirtham SM, Abraham A, Velayudhan SR, Balasubramanian P. Benjamin ESB, et al. Among authors: balasubramanian p. Cell Signal. 2024 Apr;116:111067. doi: 10.1016/j.cellsig.2024.111067. Epub 2024 Jan 27. Cell Signal. 2024. PMID: 38281615
Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.
Rajendiran V, Devaraju N, Haddad M, Ravi NS, Panigrahi L, Paul J, Gopalakrishnan C, Wyman S, Ariudainambi K, Mahalingam G, Periyasami Y, Prasad K, George A, Sukumaran D, Gopinathan S, Pai AA, Nakamura Y, Balasubramanian P, Ramalingam R, Thangavel S, Velayudhan SR, Corn JE, Mackay JP, Marepally S, Srivastava A, Crossley M, Mohankumar KM. Rajendiran V, et al. Among authors: balasubramanian p. Mol Ther. 2024 Mar 6;32(3):663-677. doi: 10.1016/j.ymthe.2024.01.023. Epub 2024 Jan 24. Mol Ther. 2024. PMID: 38273654 Free article.
Treosulfan Exposure Predicts Thalassemia-Free Survival in Patients with Beta Thalassemia Major Undergoing Allogeneic Hematopoietic Cell Transplantation.
Pai AA, Mohanan E, Panetta JC, Kulkarni UP, Illangeswaran RSS, Balakrishnan B, Jayaraman A, Edison ES, Lakshmi KM, Devasia AJ, Fouzia NA, Korula A, Abraham A, George B, Srivastava A, Mathews V, Standing JF, Balasubramanian P. Pai AA, et al. Among authors: balasubramanian p. Clin Pharmacol Ther. 2024 Jan;115(1):116-125. doi: 10.1002/cpt.3078. Epub 2023 Nov 7. Clin Pharmacol Ther. 2024. PMID: 37846495 Free PMC article.
Haploidentical Natural Killer Cell Therapy as an Adjunct to Stem Cell Transplantation for Treatment of Refractory Acute Myeloid Leukemia.
Kulkarni U, Arunachalam AK, Palani HK, Nair RR, Balasundaram N, Venkatraman A, Korula A, Selvarajan S, Lionel S, Balasubramanian P, Maddali M, Abraham A, George B, Mathews V. Kulkarni U, et al. Among authors: balasubramanian p. Cell Transplant. 2023 Jan-Dec;32:9636897231198178. doi: 10.1177/09636897231198178. Cell Transplant. 2023. PMID: 37706453 Free PMC article.
Clinical significance of end of induction measurable residual disease monitoring in B-cell acute lymphoblastic leukemia: A single center experience.
Arunachalam AK, Selvarajan S, Mani T, Janet NB, Maddali M, Lionel SA, Kulkarni U, Korula A, Aboobacker FN, Abraham A, George B, Balasubramanian P, Mathews V. Arunachalam AK, et al. Among authors: balasubramanian p. Cytometry B Clin Cytom. 2023 Nov;104(6):440-452. doi: 10.1002/cyto.b.22139. Epub 2023 Aug 9. Cytometry B Clin Cytom. 2023. PMID: 37555390
Intracranial bleeding in acute promyelocytic leukemia treated with arsenic trioxide based regimens is associated with induction mortality but not with relapse.
Kulkarni UP, Selvarajan S, Fouzia NA, Lionel S, Nair SC, Balasubramanian P, Mani T, Abraham A, George B, Mathews V. Kulkarni UP, et al. Among authors: balasubramanian p. Blood Cancer J. 2023 Jun 22;13(1):94. doi: 10.1038/s41408-023-00873-z. Blood Cancer J. 2023. PMID: 37349334 Free PMC article. No abstract available.
Modulating retinoid-X-receptor alpha (RXRA) expression sensitizes chronic myeloid leukemia cells to imatinib in vitro and reduces disease burden in vivo.
Rajamani BM, Illangeswaran RSS, Benjamin ESB, Balakrishnan B, Jebanesan DZP, Das S, Pai AA, Vidhyadharan RT, Mohan A, Karathedath S, Abraham A, Mathews V, Velayudhan SR, Balasubramanian P. Rajamani BM, et al. Among authors: balasubramanian p. Front Pharmacol. 2023 May 31;14:1187066. doi: 10.3389/fphar.2023.1187066. eCollection 2023. Front Pharmacol. 2023. PMID: 37324449 Free PMC article.
Corrigendum to "Chemotherapeutic drugs elicit stemness and metabolic alteration to mediate acquired drug-resistant phenotype in acute myeloid leukemia cell lines" [Leukemia Res. 128, 107054].
Illangeswaran RSS, Jebanesan DZP, Sivakumar KK, Vidhyadharan RT, Rajamani BM, Janet NB, David E, Velayudhan SR, Mathews V, Balasubramanian P. Illangeswaran RSS, et al. Among authors: balasubramanian p. Leuk Res. 2023 Jul;130:107329. doi: 10.1016/j.leukres.2023.107329. Epub 2023 May 29. Leuk Res. 2023. PMID: 37258357 No abstract available.
Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies.
Venkatesan V, Christopher AC, Rhiel M, Azhagiri MKK, Babu P, Walavalkar K, Saravanan B, Andrieux G, Rangaraj S, Srinivasan S, Karuppusamy KV, Jacob A, Bagchi A, Pai AA, Nakamura Y, Kurita R, Balasubramanian P, Pai R, Marepally SK, Mohankumar KM, Velayudhan SR, Boerries M, Notani D, Cathomen T, Srivastava A, Thangavel S. Venkatesan V, et al. Among authors: balasubramanian p. Mol Ther Nucleic Acids. 2023 Apr 26;32:671-688. doi: 10.1016/j.omtn.2023.04.024. eCollection 2023 Jun 13. Mol Ther Nucleic Acids. 2023. PMID: 37215154 Free PMC article.
Chemotherapeutic drugs elicit stemness and metabolic alteration to mediate acquired drug-resistant phenotype in acute myeloid leukemia cell lines.
Illangeswaran RSS, Jebanesan DZP, Sivakumar KK, Vidhyadharan RT, Rajamani BM, Janet NB, David E, Velayudhan SR, Mathews V, Balasubramanian P. Illangeswaran RSS, et al. Among authors: balasubramanian p. Leuk Res. 2023 May;128:107054. doi: 10.1016/j.leukres.2023.107054. Epub 2023 Mar 3. Leuk Res. 2023. PMID: 36906941
Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2.
George A, Ravi NS, Prasad K, Panigrahi L, Koikkara S, Rajendiran V, Devaraju N, Paul J, Pai AA, Nakamura Y, Kurita R, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR, Srivastava A, Mohankumar KM. George A, et al. Among authors: balasubramanian p. Front Genome Ed. 2022 Dec 20;4:1085111. doi: 10.3389/fgeed.2022.1085111. eCollection 2022. Front Genome Ed. 2022. PMID: 36605051 Free PMC article.
Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications.
Bagchi A, Devaraju N, Chambayil K, Rajendiran V, Venkatesan V, Sayed N, Pai AA, Nath A, David E, Nakamura Y, Balasubramanian P, Srivastava A, Thangavel S, Mohankumar KM, Velayudhan SR. Bagchi A, et al. Among authors: balasubramanian p. Sci Rep. 2022 Aug 18;12(1):14033. doi: 10.1038/s41598-022-13783-0. Sci Rep. 2022. PMID: 35982069 Free PMC article.
Endothelial Activation and Stress Index-Measured Pretransplantation Predicts Transplantation-Related Mortality in Patients with Thalassemia Major Undergoing Transplantation with Thiotepa, Treosulfan, and Fludarabine Conditioning.
Kulkarni UP, Pai AA, Kavitha ML, Selvarajan S, Lionel S, Devasia AJ, Korula A, Fouzia NA, Sindhuvi E, Abraham A, Srivastava A, Mathews V, George B, Balasubramanian P. Kulkarni UP, et al. Among authors: balasubramanian p. Transplant Cell Ther. 2022 Jul;28(7):356.e1-356.e6. doi: 10.1016/j.jtct.2022.05.001. Epub 2022 May 9. Transplant Cell Ther. 2022. PMID: 35550442 Free article.
Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.
Ravi NS, Wienert B, Wyman SK, Bell HW, George A, Mahalingam G, Vu JT, Prasad K, Bandlamudi BP, Devaraju N, Rajendiran V, Syedbasha N, Pai AA, Nakamura Y, Kurita R, Narayanasamy M, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR, Srivastava A, DeWitt MA, Crossley M, Corn JE, Mohankumar KM. Ravi NS, et al. Among authors: balasubramanian p. Elife. 2022 Feb 11;11:e65421. doi: 10.7554/eLife.65421. Elife. 2022. PMID: 35147495 Free PMC article.
Real world data with concurrent retinoic acid and arsenic trioxide for the treatment of acute promyelocytic leukemia.
Kulkarni UP, Selvarajan S, Lionel S, Prakash MA, Palani HK, Balasundaram N, Venkataraman A, Korula A, Devasia AJ, Fouzia NA, Janet NB, Nair SC, Abraham A, Mani T, Lakshmanan J, Arunachalam AK, Balasubramanian P, George B, Mathews V. Kulkarni UP, et al. Among authors: balasubramanian p. Blood Cancer J. 2022 Jan 31;12(1):22. doi: 10.1038/s41408-022-00619-3. Blood Cancer J. 2022. PMID: 35102152 Free PMC article. No abstract available.
NUDT15 c.415C>T Polymorphism Predicts 6-MP Induced Early Myelotoxicity in Patients with Acute Lymphoblastic Leukemia Undergoing Maintenance Therapy.
Pai AA, Mohan A, Benjamin ESB, Illangeswaran RSS, Xavier Raj I, Janet NB, Arunachalam AK, Kavitha ML, Kulkarni U, Devasia AJ, Fouzia NA, Abraham A, Srivastava A, George B, Mathews V, Korula A, Balasubramanian P. Pai AA, et al. Among authors: balasubramanian p. Pharmgenomics Pers Med. 2021 Oct 2;14:1303-1313. doi: 10.2147/PGPM.S325813. eCollection 2021. Pharmgenomics Pers Med. 2021. PMID: 34629890 Free PMC article.
Metabolic adaptation drives arsenic trioxide resistance in acute promyelocytic leukemia.
Balasundaram N, Ganesan S, Chendamarai E, Palani HK, Venkatraman A, Alex AA, David S, Kumar SP, Radhakrishnan NR, Yasar M, Krishna S, Korula A, Kulkarni U, Janet NB, Balasubramanian P, Mathews V. Balasundaram N, et al. Among authors: balasubramanian p. Blood Adv. 2022 Jan 25;6(2):652-663. doi: 10.1182/bloodadvances.2021005300. Blood Adv. 2022. PMID: 34625794 Free PMC article.
Systematic application of fluorescence in situ hybridization and immunophenotype profile for the identification of ZNF384 gene rearrangements in B cell acute lymphoblastic leukemia.
Janet NB, Kulkarni U, Arun AK, Bensega B, Devasia AJ, Korula A, Abraham A, George B, Mathews V, Balasubramanian P. Janet NB, et al. Among authors: balasubramanian p. Int J Lab Hematol. 2021 Aug;43(4):658-663. doi: 10.1111/ijlh.13580. Epub 2021 May 14. Int J Lab Hematol. 2021. PMID: 33988307 Free PMC article.
Mutation Profile in BCR-ABL1-Negative Myeloproliferative Neoplasms: A Single-Center Experience From India.
Maddali M, Kulkarni UP, Ravindra N, Arunachalam AK, Venkatraman A, Lionel S, Manipadam MT, Devasia AJ, Korula A, Fouzia NA, Abraham A, Srivastava A, George B, Balasubramanian P, Mathews V. Maddali M, et al. Among authors: balasubramanian p. Hematol Oncol Stem Cell Ther. 2022 Jun 1;15(2):13-20. doi: 10.1016/j.hemonc.2021.03.002. Hematol Oncol Stem Cell Ther. 2022. PMID: 33789164 Free PMC article.
BCR-ABL1 kinase domain mutation analysis by next generation sequencing detected additional mutations in chronic myeloid leukemia patients with suboptimal response to imatinib.
Benjamin ESB, Ravindra N, Rajamani BM, Anandan S, Kausalya B, Veldore V, Mathews V, Velayudhan SR, Balasubramanian P. Benjamin ESB, et al. Among authors: balasubramanian p. Leuk Lymphoma. 2021 Jun;62(6):1528-1531. doi: 10.1080/10428194.2021.1872074. Epub 2021 Jan 22. Leuk Lymphoma. 2021. PMID: 33478278 Free PMC article. No abstract available.
Plasma imatinib levels and ABCB1 polymorphism influences early molecular response and failure-free survival in newly diagnosed chronic phase CML patients.
Rajamani BM, Benjamin ESB, Abraham A, Ganesan S, Lakshmi KM, Anandan S, Karathedath S, Varatharajan S, Mohanan E, Janet NB, Srivastava VM, Ramachandran Velayudhan S, Kulkarni UP, Devasia AJ, Fouzia NA, Korula A, George B, Srivastava A, Mathews V, Balasubramanian P. Rajamani BM, et al. Among authors: balasubramanian p. Sci Rep. 2020 Nov 26;10(1):20640. doi: 10.1038/s41598-020-77140-9. Sci Rep. 2020. PMID: 33244077 Free PMC article.
Management of relapse in acute promyelocytic leukaemia treated with up-front arsenic trioxide-based regimens.
Fouzia NA, Sharma V, Ganesan S, Palani HK, Balasundaram N, David S, Kulkarni UP, Korula A, Devasia AJ, Nair SC, Janet NB, Abraham A, Mani T, Lakshmanan J, Balasubramanian P, George B, Mathews V. Fouzia NA, et al. Among authors: balasubramanian p. Br J Haematol. 2021 Jan;192(2):292-299. doi: 10.1111/bjh.17221. Epub 2020 Nov 20. Br J Haematol. 2021. PMID: 33216980 Free PMC article.
Prognostic plasma biomarkers of early complications and graft-versus-host disease in patients undergoing allogeneic hematopoietic stem cell transplantation.
Balakrishnan B, Illangeswaran RSS, Rajamani BM, Pai AA, Raj IX, Paul DZ, Lakshmi K, Mani T, Mohanan E, Kulkarni U, Devasia AJ, Fouzia NA, Korula A, Abraham A, Srivastava A, Mathews V, Paczesny S, George B, Balasubramanian P. Balakrishnan B, et al. Among authors: balasubramanian p. EJHaem. 2020 Jul;1(1):219-229. doi: 10.1002/jha2.26. Epub 2020 Jun 17. EJHaem. 2020. PMID: 32885223 Free PMC article.
Prognostic value of MRD monitoring based on BCR-ABL1 copy numbers in Philadelphia chromosome positive acute lymphoblastic leukemia.
Arunachalam AK, Janet NB, Korula A, Lakshmi KM, Kulkarni UP, Aboobacker FN, Abraham A, George B, Balasubramanian P, Mathews V. Arunachalam AK, et al. Among authors: balasubramanian p. Leuk Lymphoma. 2020 Dec;61(14):3468-3475. doi: 10.1080/10428194.2020.1811272. Epub 2020 Aug 27. Leuk Lymphoma. 2020. PMID: 32852239 Free PMC article.
A phase II study evaluating the role of bortezomib in the management of relapsed acute promyelocytic leukemia treated upfront with arsenic trioxide.
Kulkarni U, Ganesan S, Alex AA, Palani H, David S, Balasundaram N, Venkatraman A, Thenmozhi M, Jeyaseelan L, Korula A, Devasia A, Abraham A, Janet NB, Balasubramanian P, George B, Mathews V. Kulkarni U, et al. Among authors: balasubramanian p. Cancer Med. 2020 Apr;9(8):2603-2610. doi: 10.1002/cam4.2883. Epub 2020 Feb 14. Cancer Med. 2020. PMID: 32059085 Free PMC article. Clinical Trial.
Resource utilization and cost effectiveness of treating acute promyelocytic leukaemia using generic arsenic trioxide.
Bankar A, Korula A, Kulkarni UP, Devasia AJ, Na F, Lionel S, Abraham A, Balasubramanian P, Janet NB, Nair SC, S S, Jeyaseelan V, N J, Prasad J, George B, Mathews V. Bankar A, et al. Among authors: balasubramanian p. Br J Haematol. 2020 Apr;189(2):269-278. doi: 10.1111/bjh.16343. Epub 2019 Dec 21. Br J Haematol. 2020. PMID: 31863602 Free article.
Pharmacokinetics and Efficacy of Generic Melphalan Is Comparable to Innovator Formulation in Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplantation.
Pai AA, Devasia AJ, Panetta JC, Mani S, Stallon Illangeswaran RS, Mohanan E, Balakrishnan B, Lakshmi KM, Kulkarni U, Aboobacker FN, Korula A, Abraham A, Srivastava A, Mathews V, George B, Balasubramanian P. Pai AA, et al. Among authors: balasubramanian p. Clin Lymphoma Myeloma Leuk. 2020 Feb;20(2):130-135.e1. doi: 10.1016/j.clml.2019.08.013. Epub 2019 Oct 4. Clin Lymphoma Myeloma Leuk. 2020. PMID: 31791694 Free PMC article.
In Ph+BCR-ABL1P210+ acute lymphoblastic leukemia the e13a2 (B2A2) transcript is prevalent.
Baccarani M, Iacobucci I, Chiaretti S, Foà' R, Balasubramanian P, Paietta E, Foroni L, Jeromin S, Izzo B, Spinelli O, Varma N, Menif S, Terragna C, Seth T, Bidet A, Coriu D, Lunghi F, Mayer J, Scappini B, Langabeer S, Maier J, Burt E, Candoni A, Albano F, Luppi M, Zupan I, Lion T, Zadro R, di Raimondo F, Poopak B, Rege-Cambrin G, Annunziata M, Ayala A, Salinas-Viedma V, Ines Prado A, Milner B, Galimberti S, Janssen J, Polli V, Comba L, Borsellino B, Annibali O, Crugnola M, Passamonti F. Baccarani M, et al. Among authors: balasubramanian p. Leukemia. 2020 Mar;34(3):929-931. doi: 10.1038/s41375-019-0591-9. Epub 2019 Oct 8. Leukemia. 2020. PMID: 31595038 Free article. No abstract available.
A personalized approach to acute myeloid leukemia therapy: current options.
Illangeswaran RSS, Das S, Paul DZ, Mathews V, Balasubramanian P. Illangeswaran RSS, et al. Among authors: balasubramanian p. Pharmgenomics Pers Med. 2019 Aug 2;12:167-179. doi: 10.2147/PGPM.S168267. eCollection 2019. Pharmgenomics Pers Med. 2019. PMID: 31447578 Free PMC article.
Arsenic Trioxide Enhances the NK Cell Cytotoxicity Against Acute Promyelocytic Leukemia While Simultaneously Inhibiting Its Bio-Genesis.
Alex AA, Ganesan S, Palani HK, Balasundaram N, David S, Lakshmi KM, Kulkarni UP, Nisham PN, Korula A, Devasia AJ, Janet NB, Abraham A, Srivastava A, George B, Padua RA, Chomienne C, Balasubramanian P, Mathews V. Alex AA, et al. Among authors: balasubramanian p. Front Immunol. 2018 Jun 14;9:1357. doi: 10.3389/fimmu.2018.01357. eCollection 2018. Front Immunol. 2018. PMID: 29963052 Free PMC article.
88 results