Popel AS [Author] - Search Results

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Multi-Scale Spatial Analysis of the Tumor Microenvironment Reveals Features of Cabozantinib and Nivolumab Efficacy in Hepatocellular Carcinoma.

Mi H, Ho WJ, Yarchoan M, Popel AS. Mi H, et al. Among authors: popel as. Front Immunol. 2022 May 13;13:892250. doi: 10.3389/fimmu.2022.892250. eCollection 2022. Front Immunol. 2022. PMID: 35634309 Free PMC article.

Dynamic Multiscale Regulation of Perfusion Recovery in Experimental Peripheral Arterial Disease: A Mechanistic Computational Model.

Zhao C, Heuslein JL, Zhang Y, Annex BH, Popel AS. Zhao C, et al. Among authors: popel as. JACC Basic Transl Sci. 2022 Jan 5;7(1):28-50. doi: 10.1016/j.jacbts.2021.10.014. eCollection 2022 Jan. JACC Basic Transl Sci. 2022. PMID: 35128207 Free PMC article.

Systems biology of angiogenesis signaling: Computational models and omics.

Zhang Y, Wang H, Oliveira RHM, Zhao C, Popel AS. Zhang Y, et al. Among authors: popel as. WIREs Mech Dis. 2021 Dec 30:e1550. doi: 10.1002/wsbm.1550. Online ahead of print. WIREs Mech Dis. 2021. PMID: 34970866 Free PMC article. Review.

Integrating single cell sequencing with a spatial quantitative systems pharmacology model spQSP for personalized prediction of triple-negative breast cancer immunotherapy response.

Zhang S, Gong C, Ruiz-Martinez A, Wang H, Davis-Marcisak E, Deshpande A, Popel AS, Fertig EJ. Zhang S, et al. Among authors: popel as. Immunoinformatics (Amst). 2021 Oct;1-2:100002. doi: 10.1016/j.immuno.2021.100002. Epub 2021 Jul 24. Immunoinformatics (Amst). 2021. PMID: 34708216 Free PMC article.

Predictive models of response to neoadjuvant chemotherapy in muscle-invasive bladder cancer using nuclear morphology and tissue architecture.

Mi H, Bivalacqua TJ, Kates M, Seiler R, Black PC, Popel AS, Baras AS. Mi H, et al. Among authors: popel as. Cell Rep Med. 2021 Aug 27;2(9):100382. doi: 10.1016/j.xcrm.2021.100382. eCollection 2021 Sep 21. Cell Rep Med. 2021. PMID: 34622225 Free PMC article.

Protocol for simulating macrophage signal transduction and phenotype polarization using a large-scale mechanistic computational model.

Zhao C, Popel AS. Zhao C, et al. Among authors: popel as. STAR Protoc. 2021 Aug 12;2(3):100739. doi: 10.1016/j.xpro.2021.100739. eCollection 2021 Sep 17. STAR Protoc. 2021. PMID: 34430914 Free PMC article.

A systems biology model of junctional localization and downstream signaling of the Ang-Tie signaling pathway.

Zhang Y, Kontos CD, Annex BH, Popel AS. Zhang Y, et al. Among authors: popel as. NPJ Syst Biol Appl. 2021 Aug 20;7(1):34. doi: 10.1038/s41540-021-00194-6. NPJ Syst Biol Appl. 2021. PMID: 34417472 Free PMC article.

A Spatial Quantitative Systems Pharmacology Platform spQSP-IO for Simulations of Tumor-Immune Interactions and Effects of Checkpoint Inhibitor Immunotherapy.

Gong C, Ruiz-Martinez A, Kimko H, Popel AS. Gong C, et al. Among authors: popel as. Cancers (Basel). 2021 Jul 26;13(15):3751. doi: 10.3390/cancers13153751. Cancers (Basel). 2021. PMID: 34359653 Free PMC article.

A data-driven computational model enables integrative and mechanistic characterization of dynamic macrophage polarization.

Zhao C, Medeiros TX, Sové RJ, Annex BH, Popel AS. Zhao C, et al. Among authors: popel as. iScience. 2021 Jan 29;24(2):102112. doi: 10.1016/j.isci.2021.102112. eCollection 2021 Feb 19. iScience. 2021. PMID: 33659877 Free PMC article.

Quantitative Systems Pharmacology Modeling of PBMC-Humanized Mouse to Facilitate Preclinical Immuno-oncology Drug Development.

Ma H, Pilvankar M, Wang J, Giragossian C, Popel AS. Ma H, et al. Among authors: popel as. ACS Pharmacol Transl Sci. 2020 Dec 3;4(1):213-225. doi: 10.1021/acsptsci.0c00178. eCollection 2021 Feb 12. ACS Pharmacol Transl Sci. 2020. PMID: 33615174 Free PMC article.

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