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Neural tissue in ascidian embryos is induced by FGF9/16/20, acting via a combination of maternal GATA and Ets transcription factors.
Bertrand V, Hudson C, Caillol D, Popovici C, Lemaire P. Bertrand V, et al. Among authors: popovici c. Cell. 2003 Nov 26;115(5):615-27. doi: 10.1016/s0092-8674(03)00928-0. Cell. 2003. PMID: 14651852
Phylogenetic analysis of Ciona intestinalis gene superfamilies supports the hypothesis of successive gene expansions.
Leveugle M, Prat K, Popovici C, Birnbaum D, Coulier F. Leveugle M, et al. Among authors: popovici c. J Mol Evol. 2004 Feb;58(2):168-81. doi: 10.1007/s00239-003-2538-y. J Mol Evol. 2004. PMID: 15042337
We have searched available sequences from the small marine ascidian C. intestinalis for orthologs of members of five vertebrate superfamilies, including tyrosine kinase receptors, ETS, FOX and SOX transcription factors, and WNT secreted regulatory factors, and conducted ph …
We have searched available sequences from the small marine ascidian C. intestinalis for orthologs of members of five vertebrate super …
Intracellular trafficking of LET-756, a fibroblast growth factor of C. elegans, is controlled by a balance of export and nuclear signals.
Popovici C, Fallet M, Marguet D, Birnbaum D, Roubin R. Popovici C, et al. Exp Cell Res. 2006 May 15;312(9):1484-95. doi: 10.1016/j.yexcr.2006.01.012. Epub 2006 Feb 20. Exp Cell Res. 2006. PMID: 16487967
LET-756 is one of the two FGFs of the nematode C. elegans. Re-introduction of LET-756 in a null mutant strain restores viability, allowing the study of structural requirements for LET-756 trafficking and function. ...
LET-756 is one of the two FGFs of the nematode C. elegans. Re-introduction of LET-756 in a null mutant strain restores viability, all …
A pair as a minimum: the two fibroblast growth factors of the nematode Caenorhabditis elegans.
Birnbaum D, Popovici C, Roubin R. Birnbaum D, et al. Among authors: popovici c. Dev Dyn. 2005 Feb;232(2):247-55. doi: 10.1002/dvdy.20219. Dev Dyn. 2005. PMID: 15614779 Review.
C. elegans has a single FGFR (EGL-15) with two functionally exclusive isoforms, and two FGFs (LET-756 and EGL-17), which play distinct roles: an essential function for the former, and guidance of the migrating sex myoblasts for the latter. ...
C. elegans has a single FGFR (EGL-15) with two functionally exclusive isoforms, and two FGFs (LET-756 and EGL-17), which play distinc
Functional phylogeny relates LET-756 to fibroblast growth factor 9.
Popovici C, Conchonaud F, Birnbaum D, Roubin R. Popovici C, et al. J Biol Chem. 2004 Sep 17;279(38):40146-52. doi: 10.1074/jbc.M405795200. Epub 2004 Jun 15. J Biol Chem. 2004. PMID: 15199049
Chimera containing the core of C. intestinalis FGF9/16/20, a potential ortholog of FGF9 lacking the complete EFISIA motif, was not able to rescue the lethal phenotype or be secreted. ...
Chimera containing the core of C. intestinalis FGF9/16/20, a potential ortholog of FGF9 lacking the complete EFISIA motif, was not ab …
let-756, a C. elegans fgf essential for worm development.
Roubin R, Naert K, Popovici C, Vatcher G, Coulier F, Thierry-Mieg J, Pontarotti P, Birnbaum D, Baillie D, Thierry-Mieg D. Roubin R, et al. Among authors: popovici c. Oncogene. 1999 Nov 18;18(48):6741-7. doi: 10.1038/sj.onc.1203074. Oncogene. 1999. PMID: 10597282
A sequence encoding a putative protein presenting 30-40% identity with the conserved core of vertebrate FGFs has been identified by the C. elegans sequencing consortium. ...The truncated protein retains the FGF core but lacks a C-termins portion. These worms are sma …
A sequence encoding a putative protein presenting 30-40% identity with the conserved core of vertebrate FGFs has been identified by the C
Assignment of the centrosomal protein 110 gene (Cep110) to mouse chromosome bands 2B-C1 by in situ hybridization.
Popovici C, Mattéi MG, Rattner JB, Birnbaum D, Pébusque MJ. Popovici C, et al. Cytogenet Cell Genet. 2000;89(3-4):216-7. doi: 10.1159/000015616. Cytogenet Cell Genet. 2000. PMID: 10965126 No abstract available.
An evolutionary history of the FGF superfamily.
Popovici C, Roubin R, Coulier F, Birnbaum D. Popovici C, et al. Bioessays. 2005 Aug;27(8):849-57. doi: 10.1002/bies.20261. Bioessays. 2005. PMID: 16015590
The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fibroblast growth factor receptor 1.
Popovici C, Zhang B, Grégoire MJ, Jonveaux P, Lafage-Pochitaloff M, Birnbaum D, Pébusque MJ. Popovici C, et al. Blood. 1999 Feb 15;93(4):1381-9. Blood. 1999. PMID: 9949182
Whole ARX gene duplication is compatible with normal intellectual development.
Popovici C, Busa T, Boute O, Thuresson AC, Perret O, Sigaudy S, Södergren T, Andrieux J, Moncla A, Philip N. Popovici C, et al. Am J Med Genet A. 2014 Sep;164A(9):2324-7. doi: 10.1002/ajmg.a.36564. Epub 2014 Jul 7. Am J Med Genet A. 2014. PMID: 25044608
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