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T1D progression is associated with loss of CD3+CD56+ regulatory T cells that control CD8+ T cell effector functions.
Terrazzano G, Bruzzaniti S, Rubino V, Santopaolo M, Palatucci AT, Giovazzino A, La Rocca C, de Candia P, Puca A, Perna F, Procaccini C, De Rosa V, Porcellini C, De Simone S, Fattorusso V, Porcellini A, Mozzillo E, Troncone R, Franzese A, Ludvigsson J, Matarese G, Ruggiero G, Galgani M. Terrazzano G, et al. Among authors: porcellini c, porcellini a. Nat Metab. 2020 Feb;2(2):142-152. doi: 10.1038/s42255-020-0173-1. Epub 2020 Feb 17. Nat Metab. 2020. PMID: 32500117 Free PMC article.
An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness.
Procaccini C, De Rosa V, Galgani M, Abanni L, Calì G, Porcellini A, Carbone F, Fontana S, Horvath TL, La Cava A, Matarese G. Procaccini C, et al. Among authors: porcellini a. Immunity. 2010 Dec 14;33(6):929-41. doi: 10.1016/j.immuni.2010.11.024. Epub 2010 Dec 9. Immunity. 2010. PMID: 21145759 Free PMC article.
Glycolysis controls the induction of human regulatory T cells by modulating the expression of FOXP3 exon 2 splicing variants.
De Rosa V, Galgani M, Porcellini A, Colamatteo A, Santopaolo M, Zuchegna C, Romano A, De Simone S, Procaccini C, La Rocca C, Carrieri PB, Maniscalco GT, Salvetti M, Buscarinu MC, Franzese A, Mozzillo E, La Cava A, Matarese G. De Rosa V, et al. Among authors: porcellini a. Nat Immunol. 2015 Nov;16(11):1174-84. doi: 10.1038/ni.3269. Epub 2015 Sep 28. Nat Immunol. 2015. PMID: 26414764 Free PMC article.
The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements.
Procaccini C, Carbone F, Di Silvestre D, Brambilla F, De Rosa V, Galgani M, Faicchia D, Marone G, Tramontano D, Corona M, Alviggi C, Porcellini A, La Cava A, Mauri P, Matarese G. Procaccini C, et al. Among authors: porcellini a. Immunity. 2016 Feb 16;44(2):406-21. doi: 10.1016/j.immuni.2016.01.028. Immunity. 2016. PMID: 26885861 Free PMC article.
The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements.
Procaccini C, Carbone F, Di Silvestre D, Brambilla F, De Rosa V, Galgani M, Faicchia D, Marone G, Tramontano D, Corona M, Alviggi C, Porcellini A, La Cava A, Mauri P, Matarese G. Procaccini C, et al. Among authors: porcellini a. Immunity. 2016 Mar 15;44(3):712. doi: 10.1016/j.immuni.2016.02.022. Epub 2016 Mar 15. Immunity. 2016. PMID: 28843073 Free PMC article. No abstract available.
An immunometabolic pathomechanism for chronic obstructive pulmonary disease.
Bruzzaniti S, Bocchino M, Santopaolo M, Calì G, Stanziola AA, D'Amato M, Esposito A, Barra E, Garziano F, Micillo T, Zuchegna C, Romano A, De Simone S, Zuccarelli B, Mottola M, De Rosa V, Porcellini A, Perna F, Matarese G, Galgani M. Bruzzaniti S, et al. Among authors: porcellini a. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15625-15634. doi: 10.1073/pnas.1906303116. Epub 2019 Jul 15. Proc Natl Acad Sci U S A. 2019. PMID: 31308239 Free PMC article.
High levels of blood circulating immune checkpoint molecules in children with new-onset type 1 diabetes are associated with the risk of developing an additional autoimmune disease.
Bruzzaniti S, Piemonte E, Mozzillo E, Bruzzese D, Lepore MT, Carbone F, de Candia P, Strollo R, Porcellini A, Marigliano M, Maffeis C, Bifulco M, Ludvigsson J, Franzese A, Matarese G, Galgani M. Bruzzaniti S, et al. Among authors: porcellini a. Diabetologia. 2022 Aug;65(8):1390-1397. doi: 10.1007/s00125-022-05724-3. Epub 2022 May 25. Diabetologia. 2022. PMID: 35610521
201 results