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Page 1
Periodontitis: A Plausible Modifiable Risk Factor for Neurodegenerative Diseases? A Comprehensive Review.
Plachokova AS, Gjaltema J, Hagens ERC, Hashemi Z, Knüppe TBA, Kootstra TJM, Visser A, Bloem BR. Plachokova AS, et al. Int J Mol Sci. 2024 Apr 19;25(8):4504. doi: 10.3390/ijms25084504. Int J Mol Sci. 2024. PMID: 38674088 Free PMC article. Review.
Results show an association between periodontitis and Alzheimer's disease, with odds ratios of 3 to 5. A bidirectional relationship is suspected. For Parkinson's disease (PD), current evidence for an association appears to be weak, although poor oral h …
Results show an association between periodontitis and Alzheimer's disease, with odds ratios of 3 to 5. A bidirectional relationship i …
Ultrastructural localization of Porphyromonas gingivalis gingipains in the substantia nigra of Parkinson's disease brains.
Ermini F, Low VF, Song JJ, Tan AYS, Faull RLM, Dragunow M, Curtis MA, Dominy SS. Ermini F, et al. NPJ Parkinsons Dis. 2024 Apr 25;10(1):90. doi: 10.1038/s41531-024-00705-2. NPJ Parkinsons Dis. 2024. PMID: 38664405 Free PMC article.
Gingipains are protease virulence factors produced by Porphyromonas gingivalis, a Gram-negative bacterium best known for its role in chronic periodontitis. ...Since AD and Parkinson's disease (PD) share some overlapping pathologic features, incl …
Gingipains are protease virulence factors produced by Porphyromonas gingivalis, a Gram-negative bacterium best known for its r …
The Impact of Prevotella on Neurobiology in Aging: Deciphering Dendritic Cell Activity and Inflammatory Dynamics.
Ahmed HS. Ahmed HS. Mol Neurobiol. 2024 Nov;61(11):9240-9251. doi: 10.1007/s12035-024-04156-x. Epub 2024 Apr 13. Mol Neurobiol. 2024. PMID: 38613648 Review.
Studies implicate various Prevotella species in specific diseases. Prevotella nigrescens and Porphyromonas gingivalis were linked to periodontal disease, promoting immune responses and influencing T helper type 17 (Th17) cells. ...Prevotella's role in neuroin …
Studies implicate various Prevotella species in specific diseases. Prevotella nigrescens and Porphyromonas gingivalis were lin …
Oral Microbiota and Porphyromonas gingivalis Kgp Genotypes Altered in Parkinson's Disease with Mild Cognitive Impairment.
Li D, Ren T, Li H, Huang M, Chen J, He Q, Lv W, Liu H, Xu R, Zhang X. Li D, et al. Mol Neurobiol. 2024 Nov;61(11):8631-8639. doi: 10.1007/s12035-024-04119-2. Epub 2024 Mar 27. Mol Neurobiol. 2024. PMID: 38536604
Cognitive impairment (CI) is a common complication of the non-motor symptoms in Parkinson's disease (PD), including PD with mild cognitive impairment (PD-MCI) and PD dementia. Recent studies reported the oral dysbiosis in PD and CI, respectively. Porphyrom …
Cognitive impairment (CI) is a common complication of the non-motor symptoms in Parkinson's disease (PD), including PD …
Glucose-6-Phosphatase-Dehydrogenase activity as modulative association between Parkinson's disease and periodontitis.
Laugisch O, Ruppert-Jungck MC, Auschill TM, Eick S, Sculean A, Heumann C, Timmermann L, Pedrosa DJ, Eggers C, Arweiler NB. Laugisch O, et al. Front Cell Infect Microbiol. 2024 Feb 7;14:1298546. doi: 10.3389/fcimb.2024.1298546. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38404290 Free PMC article.
The association between periodontitis (PD) and Parkinson's disease (PK) is discussed due to the inflammatory component of neurodegenerative processes. PK severity and affected areas were determined using the following neuropsychological tests: Unified Park …
The association between periodontitis (PD) and Parkinson's disease (PK) is discussed due to the inflammatory component …
Porphyromonas gingivalis, neuroinflammation and Alzheimer's disease.
Owoyele PV, Malekzadeh S. Owoyele PV, et al. Niger J Physiol Sci. 2022 Dec 31;37(2):157-164. doi: 10.54548/njps.v37i2.1. Niger J Physiol Sci. 2022. PMID: 38243562 Review.
The oral microbiota dysbiosis, as well as lifestyle, geographical location, drug consumption, and dietary habits, are involved in the incidence and progression of dementia, Mild Cognitive Impairment (MCI), and some diseases such as obesity, diabetes, cardiovascular disease …
The oral microbiota dysbiosis, as well as lifestyle, geographical location, drug consumption, and dietary habits, are involved in the incide …
Association between periodontitis and cognitive impairment in adults.
Goyal L, Gupta S, Perambudhuru Y. Goyal L, et al. Evid Based Dent. 2023 Sep;24(3):123-124. doi: 10.1038/s41432-023-00915-2. Epub 2023 Jul 11. Evid Based Dent. 2023. PMID: 37433922
Search terms used were related to gingiva, oral bacteria like Porphyromonas gingivalis, gum inflammation, periodontitis, dementia, neuroinflammation, cognitive impairment, Alzheimer's disease, Parkinson disease. ...Comparability among the groups …
Search terms used were related to gingiva, oral bacteria like Porphyromonas gingivalis, gum inflammation, periodontitis, demen …
Anaerobes in specific infectious and noninfectious diseases: new developments.
Boyanova L, Markovska R, Yordanov D, Gergova R, Hadzhiyski P. Boyanova L, et al. Anaerobe. 2023 Jun;81:102714. doi: 10.1016/j.anaerobe.2023.102714. Anaerobe. 2023. PMID: 37349047 Review.
A link of subgingival Porphyromonas gingivalis with cardiovascular diseases was reported. Decreased Roseburia abundance was observed in the gut of Alzheimer's and Parkinson's disease patients. ...Fusobacterium nucleatum was implicated in the dev …
A link of subgingival Porphyromonas gingivalis with cardiovascular diseases was reported. Decreased Roseburia abundance was ob …
High resolution 16S rRNA gene Next Generation Sequencing study of brain areas associated with Alzheimer's and Parkinson's disease.
Emery DC, Davies M, Cerajewska TL, Taylor J, Hazell M, Paterson A, Allen-Birt SJ, West NX. Emery DC, et al. Front Aging Neurosci. 2022 Dec 9;14:1026260. doi: 10.3389/fnagi.2022.1026260. eCollection 2022. Front Aging Neurosci. 2022. PMID: 36570533 Free PMC article.
INTRODUCTION: Alzheimer's (AD) and Parkinson's disease (PD) are neurodegenerative conditions characterized by incremental deposition of beta-amyloid (Abeta) and alpha-synuclein in AD and PD brain, respectively, in relatively conserved patterns. ...There is ev …
INTRODUCTION: Alzheimer's (AD) and Parkinson's disease (PD) are neurodegenerative conditions characterized by increment …
Antibodies against HSV-1 and Curli Show the Highest Correlation in Parkinson's Disease Patients in Comparison to Healthy Controls.
Jasemi S, Paulus K, Noli M, Simula ER, Ruberto S, Sechi LA. Jasemi S, et al. Int J Mol Sci. 2022 Nov 26;23(23):14816. doi: 10.3390/ijms232314816. Int J Mol Sci. 2022. PMID: 36499141 Free PMC article.
Parkinson's disease (PD) is a neurodegenerative disorder involving the accumulation of alpha-synuclein (alpha-syn)/Lewy bodies in the brain and -enteric nervous system. ...Polyclonal IgG antibodies (Abs) were detected against peptides derived from alpha-syn ( …
Parkinson's disease (PD) is a neurodegenerative disorder involving the accumulation of alpha-synuclein (alpha-syn)/Lewy …
18 results