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676 results

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Page 1
Porphyromonas gingivalis induces cardiovascular dysfunction.
Stanisic D, Jeremic N, Singh M, Pushpakumar S, Mokshagundam SPL, Tyagi SC. Stanisic D, et al. Can J Physiol Pharmacol. 2023 Aug 1;101(8):413-424. doi: 10.1139/cjpp-2022-0392. Epub 2023 May 19. Can J Physiol Pharmacol. 2023. PMID: 37207360
Porphyromonas gingivalis (P. gingivalis) is one of the most responsible periodontopathogenic bacteria in the development of periodontal disease (PD); however, its role in the development of other diseases still needs to be understood, specially its implicatio
Porphyromonas gingivalis (P. gingivalis) is one of the most responsible periodontopathogenic bacteria in the developmen
Roles of Porphyromonas gingivalis and its virulence factors in periodontitis.
Xu W, Zhou W, Wang H, Liang S. Xu W, et al. Adv Protein Chem Struct Biol. 2020;120:45-84. doi: 10.1016/bs.apcsb.2019.12.001. Epub 2020 Jan 10. Adv Protein Chem Struct Biol. 2020. PMID: 32085888 Free PMC article. Review.
Periodontitis is associated with various systemic diseases, including cardiovascular, respiratory, musculoskeletal, and reproductive system related abnormalities. Recent theory attributes the pathogenesis of periodontitis to oral microbial dysbiosis, in which Por
Periodontitis is associated with various systemic diseases, including cardiovascular, respiratory, musculoskeletal, and reproductive …
BMAL1-Downregulation Aggravates Porphyromonas Gingivalis-Induced Atherosclerosis by Encouraging Oxidative Stress.
Xie M, Tang Q, Nie J, Zhang C, Zhou X, Yu S, Sun J, Cheng X, Dong N, Hu Y, Chen L. Xie M, et al. Circ Res. 2020 Mar 13;126(6):e15-e29. doi: 10.1161/CIRCRESAHA.119.315502. Epub 2020 Feb 11. Circ Res. 2020. PMID: 32078488 Free article.
In addition to risk factors associated with the cardiovascular system itself, pathogenic bacteria such as the periodontitis-associated Porphyromonas gingivalis (P gingivalis) are also closely correlated with the development of atherosclerosis, b …
In addition to risk factors associated with the cardiovascular system itself, pathogenic bacteria such as the periodontitis-as …
Porphyromonas gingivalis aggravates atherosclerotic plaque instability by promoting lipid-laden macrophage necroptosis.
Huang X, Xie M, Wang Y, Lu X, Mei F, Zhang K, Yang X, Chen G, Yin Y, Feng G, Song W, Dong N, Deng X, Wang S, Chen L. Huang X, et al. Signal Transduct Target Ther. 2025 May 23;10(1):171. doi: 10.1038/s41392-025-02251-6. Signal Transduct Target Ther. 2025. PMID: 40404630 Free PMC article.
At advanced phases of atherosclerosis, the rupture and thrombogenesis of vulnerable plaques emerge as primary triggers for acute cardiovascular events and fatalities. Pathogenic infection such as periodontitis-associated Porphyromonas gingivalis (Pg) has been …
At advanced phases of atherosclerosis, the rupture and thrombogenesis of vulnerable plaques emerge as primary triggers for acute cardiova
The Role of Porphyromonas gingivalis Outer Membrane Vesicles in Periodontal Disease and Related Systemic Diseases.
Zhang Z, Liu D, Liu S, Zhang S, Pan Y. Zhang Z, et al. Front Cell Infect Microbiol. 2021 Jan 28;10:585917. doi: 10.3389/fcimb.2020.585917. eCollection 2020. Front Cell Infect Microbiol. 2021. PMID: 33585266 Free PMC article. Review.
Periodontal disease is a chronic infectious disease associated with a variety of bacteria, which can cause damage to the periodontal support structure and affect a variety of systemic system diseases such as cancer, cardiovascular disease, diabetes, rheumatoid arthr …
Periodontal disease is a chronic infectious disease associated with a variety of bacteria, which can cause damage to the periodontal support …
Atrial Translocation of Porphyromonas gingivalis Exacerbates Atrial Fibrosis and Atrial Fibrillation.
Miyauchi S, Kawada-Matsuo M, Furusho H, Nishi H, Nakajima A, Phat PT, Shiba F, Kitagawa M, Ouhara K, Oda N, Tokuyama T, Okubo Y, Okamura S, Takasaki T, Takahashi S, Hiyama T, Kawaguchi H, Komatsuzawa H, Miyauchi M, Nakano Y. Miyauchi S, et al. Circulation. 2025 May 27;151(21):1527-1540. doi: 10.1161/CIRCULATIONAHA.124.071310. Epub 2025 Mar 18. Circulation. 2025. PMID: 40099365
BACKGROUND: Recent studies have indicated an association between periodontitis and atrial fibrillation (AF), although the underlying mechanisms remain unclear. Porphyromonas gingivalis (P ginigivalis) is a causative agent of periodontal disease and is highly pathoge …
BACKGROUND: Recent studies have indicated an association between periodontitis and atrial fibrillation (AF), although the underlying mechani …
Porphyromonas gingivalis bacteremia increases the permeability of the blood-brain barrier via the Mfsd2a/Caveolin-1 mediated transcytosis pathway.
Lei S, Li J, Yu J, Li F, Pan Y, Chen X, Ma C, Zhao W, Tang X. Lei S, et al. Int J Oral Sci. 2023 Jan 12;15(1):3. doi: 10.1038/s41368-022-00215-y. Int J Oral Sci. 2023. PMID: 36631446 Free PMC article.
An in vitro BBB model infected with P. gingivalis was also established. We found that the infiltration of Evans blue dye and Albumin protein deposition in the rat brain tissues were increased in the rat brain tissues with P. gingivalis bacteremia and P. gingivali
An in vitro BBB model infected with P. gingivalis was also established. We found that the infiltration of Evans blue dye and Albumin …
Cyclic di-AMP Rescues Porphyromonas gingivalis-Aggravated Atherosclerosis.
Wu Q, Li Z, Zhang Y, Luo K, Xu X, Li J, Peng X, Zhou X. Wu Q, et al. J Dent Res. 2023 Jul;102(7):785-794. doi: 10.1177/00220345231162344. Epub 2023 Apr 8. J Dent Res. 2023. PMID: 37029659
Growing evidence demonstrates the relationship between periodontitis and atherosclerotic cardiovascular diseases. The periodontal pathogen Porphyromonas gingivalis (Pg) has been shown to contribute to the progression of atherosclerosis. ...
Growing evidence demonstrates the relationship between periodontitis and atherosclerotic cardiovascular diseases. The periodontal pat …
Effects and mechanisms of Porphyromonas gingivalis outer membrane vesicles induced cardiovascular injury.
Guo J, Lin K, Wang S, He X, Huang Z, Zheng M. Guo J, et al. BMC Oral Health. 2024 Jan 19;24(1):112. doi: 10.1186/s12903-024-03886-7. BMC Oral Health. 2024. PMID: 38243239 Free PMC article.
BACKGROUND: The outer membrane vesicles (OMVs) derived from Porphyromonas gingivalis (P. gingivalis) have long been acknowledged for their crucial role in the initiation of periodontitis. However, the implications of P. gingivalis OMVs in the context o …
BACKGROUND: The outer membrane vesicles (OMVs) derived from Porphyromonas gingivalis (P. gingivalis) have long been ack …
Invasion strategies of the oral pathogen porphyromonas gingivalis: implications for cardiovascular disease.
Deshpande RG, Khan M, Genco CA. Deshpande RG, et al. Invasion Metastasis. 1998-1999;18(2):57-69. doi: 10.1159/000024499. Invasion Metastasis. 1998. PMID: 10364686 Review.
The investigation of invasion by the periopathogen Porphyromonas gingivalis is in its infancy in comparison with that of the enteric pathogens. ...The ability to multiply in and to activate endothelial cells may be one of the pathogenic mechanisms exerted by P. g
The investigation of invasion by the periopathogen Porphyromonas gingivalis is in its infancy in comparison with that of the e …
676 results