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Safety and tolerability of the γ-secretase inhibitor avagacestat in a phase 2 study of mild to moderate Alzheimer disease.
Coric V, van Dyck CH, Salloway S, Andreasen N, Brody M, Richter RW, Soininen H, Thein S, Shiovitz T, Pilcher G, Colby S, Rollin L, Dockens R, Pachai C, Portelius E, Andreasson U, Blennow K, Soares H, Albright C, Feldman HH, Berman RM. Coric V, et al. Among authors: portelius e. Arch Neurol. 2012 Nov;69(11):1430-40. doi: 10.1001/archneurol.2012.2194. Arch Neurol. 2012. PMID: 22892585 Clinical Trial.
Characterization of tau in cerebrospinal fluid using mass spectrometry.
Portelius E, Hansson SF, Tran AJ, Zetterberg H, Grognet P, Vanmechelen E, Höglund K, Brinkmalm G, Westman-Brinkmalm A, Nordhoff E, Blennow K, Gobom J. Portelius E, et al. J Proteome Res. 2008 May;7(5):2114-20. doi: 10.1021/pr7008669. Epub 2008 Mar 20. J Proteome Res. 2008. PMID: 18351740
Synaptic retrogenesis and amyloid-beta in Alzheimer's disease.
Wasling P, Daborg J, Riebe I, Andersson M, Portelius E, Blennow K, Hanse E, Zetterberg H. Wasling P, et al. Among authors: portelius e. J Alzheimers Dis. 2009;16(1):1-14. doi: 10.3233/JAD-2009-0918. J Alzheimers Dis. 2009. PMID: 19158416 Review.
Proteomics/peptidomics tools to find CSF biomarkers for neurodegenerative diseases.
Westman-Brinkmalm A, Ruetschi U, Portelius E, Andreasson U, Brinkmalm G, Karlsson G, Hansson S, Zetterberg H, Blennow K. Westman-Brinkmalm A, et al. Among authors: portelius e. Front Biosci (Landmark Ed). 2009 Jan 1;14(5):1793-806. doi: 10.2741/3341. Front Biosci (Landmark Ed). 2009. PMID: 19273163 Free article. Review.
156 results