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3-aminobenzamide and/or O6-benzylguanine evaluated as an adjuvant to temozolomide or BCNU treatment in cell lines of variable mismatch repair status and O6-alkylguanine-DNA alkyltransferase activity.
Wedge SR, Porteous JK, Newlands ES. Wedge SR, et al. Among authors: porteous jk. Br J Cancer. 1996 Oct;74(7):1030-6. doi: 10.1038/bjc.1996.485. Br J Cancer. 1996. PMID: 8855970 Free PMC article.
In vitro evaluation of temozolomide combined with X-irradiation.
Wedge SR, Porteous JK, Glaser MG, Marcus K, Newlands ES. Wedge SR, et al. Among authors: porteous jk. Anticancer Drugs. 1997 Jan;8(1):92-7. doi: 10.1097/00001813-199701000-00013. Anticancer Drugs. 1997. PMID: 9147618
Potentiation of temozolomide-induced cytotoxicity: a comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors.
Boulton S, Pemberton LC, Porteous JK, Curtin NJ, Griffin RJ, Golding BT, Durkacz BW. Boulton S, et al. Among authors: porteous jk. Br J Cancer. 1995 Oct;72(4):849-56. doi: 10.1038/bjc.1995.423. Br J Cancer. 1995. PMID: 7547230 Free PMC article.
Effect of single and multiple administration of an O6-benzylguanine/temozolomide combination: an evaluation in a human melanoma xenograft model.
Wedge SR, Porteous JK, Newlands ES. Wedge SR, et al. Among authors: porteous jk. Cancer Chemother Pharmacol. 1997;40(3):266-72. doi: 10.1007/s002800050657. Cancer Chemother Pharmacol. 1997. PMID: 9219512
Novel potent inhibitors of the DNA repair enzyme poly(ADP-ribose)polymerase (PARP).
Griffin RJ, Pemberton LC, Rhodes D, Bleasdale C, Bowman K, Calvert AH, Curtin NJ, Durkacz BW, Newell DR, Porteous JK, et al. Griffin RJ, et al. Among authors: porteous jk. Anticancer Drug Des. 1995 Sep;10(6):507-14. Anticancer Drug Des. 1995. PMID: 7575991 No abstract available.
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