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Cyclin B1 and CDK1: nuclear localization and upstream regulators.
Porter LA, Donoghue DJ. Porter LA, et al. Prog Cell Cycle Res. 2003;5:335-47. Prog Cell Cycle Res. 2003. PMID: 14593728 Review.
The tumor suppressor tuberin regulates mitotic onset through the cellular localization of cyclin B1.
Fidalgo da Silva E, Ansari SB, Maimaiti J, Barnes EA, Kong-Beltran M, Donoghue DJ, Porter LA. Fidalgo da Silva E, et al. Among authors: porter la. Cell Cycle. 2011 Sep 15;10(18):3129-39. doi: 10.4161/cc.10.18.17296. Epub 2011 Sep 15. Cell Cycle. 2011. PMID: 21900748
Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins.
McGrath DA, Fifield BA, Marceau AH, Tripathi S, Porter LA, Rubin SM. McGrath DA, et al. Among authors: porter la. EMBO J. 2017 Aug 1;36(15):2251-2262. doi: 10.15252/embj.201796905. Epub 2017 Jun 30. EMBO J. 2017. PMID: 28666995 Free PMC article.
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27.
McAndrew CW, Gastwirt RF, Meyer AN, Porter LA, Donoghue DJ. McAndrew CW, et al. Among authors: porter la. Cell Cycle. 2007 Aug 1;6(15):1937-45. doi: 10.4161/cc.6.15.4520. Epub 2007 May 30. Cell Cycle. 2007. PMID: 17671428
Spy1 interacts with p27Kip1 to allow G1/S progression.
Porter LA, Kong-Beltran M, Donoghue DJ. Porter LA, et al. Mol Biol Cell. 2003 Sep;14(9):3664-74. doi: 10.1091/mbc.e02-12-0820. Epub 2003 Jul 11. Mol Biol Cell. 2003. PMID: 12972555 Free PMC article.
Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2.
Porter LA, Dellinger RW, Tynan JA, Barnes EA, Kong M, Lenormand JL, Donoghue DJ. Porter LA, et al. J Cell Biol. 2002 Apr 29;157(3):357-66. doi: 10.1083/jcb.200109045. Epub 2002 Apr 29. J Cell Biol. 2002. PMID: 11980914 Free PMC article.
Human Spy1 promotes survival of mammalian cells following DNA damage.
Barnes EA, Porter LA, Lenormand JL, Dellinger RW, Donoghue DJ. Barnes EA, et al. Among authors: porter la. Cancer Res. 2003 Jul 1;63(13):3701-7. Cancer Res. 2003. PMID: 12839962
Nuclear localization of cyclin B1 regulates DNA damage-induced apoptosis.
Porter LA, Cukier IH, Lee JM. Porter LA, et al. Blood. 2003 Mar 1;101(5):1928-33. doi: 10.1182/blood-2002-04-1103. Epub 2002 Nov 7. Blood. 2003. PMID: 12424202
Abundance of cyclin B1 regulates gamma-radiation-induced apoptosis.
Porter LA, Singh G, Lee JM. Porter LA, et al. Blood. 2000 Apr 15;95(8):2645-50. Blood. 2000. PMID: 10753846
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