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Effects of increased glucokinase gene copy number on glucose homeostasis and hepatic glucose metabolism.
Niswender KD, Shiota M, Postic C, Cherrington AD, Magnuson MA. Niswender KD, et al. Among authors: postic c. J Biol Chem. 1997 Sep 5;272(36):22570-5. doi: 10.1074/jbc.272.36.22570. J Biol Chem. 1997. PMID: 9278411
The relationship between glucokinase (GK) gene copy number and glucose homeostasis was studied in transgenic mice with additional copies of the entire GK gene locus (Niswender, K. D., Postic, C., Jetton, T. L., Bennett, B. D., Piston, D. W., Efrat, S., and Magnuson, …
The relationship between glucokinase (GK) gene copy number and glucose homeostasis was studied in transgenic mice with additional copies of …
Cell-specific expression and regulation of a glucokinase gene locus transgene.
Niswender KD, Postic C, Jetton TL, Bennett BD, Piston DW, Efrat S, Magnuson MA. Niswender KD, et al. Among authors: postic c. J Biol Chem. 1997 Sep 5;272(36):22564-9. doi: 10.1074/jbc.272.36.22564. J Biol Chem. 1997. PMID: 9278410
Pancreatic islets displayed increased GK immunoreactivity and NAD(P)H responses to glucose, but only when isolated and cultured in 20 mM glucose, as a result of the hypoglycemic phenotype of these mice (Niswender, K. D., Shiota, M., Postic, C., Cherrington, A. D., a …
Pancreatic islets displayed increased GK immunoreactivity and NAD(P)H responses to glucose, but only when isolated and cultured in 20 mM glu …
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