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Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains.
Arakhamia T, Lee CE, Carlomagno Y, Duong DM, Kundinger SR, Wang K, Williams D, DeTure M, Dickson DW, Cook CN, Seyfried NT, Petrucelli L, Fitzpatrick AWP. Arakhamia T, et al. Cell. 2020 Feb 20;180(4):633-644.e12. doi: 10.1016/j.cell.2020.01.027. Epub 2020 Feb 6. Cell. 2020. PMID: 32032505 Free PMC article.
Here, we use cryo-electron microscopy (cryo-EM) to determine the structures of tau filaments from corticobasal degeneration (CBD) human brain tissue. Cryo-EM and mass spectrometry of tau filaments from CBD reveal that this conformer is heavily decorated with posttransla …
Here, we use cryo-electron microscopy (cryo-EM) to determine the structures of tau filaments from corticobasal degeneration (CBD) hum …
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains.
Arakhamia T, Lee CE, Carlomagno Y, Kumar M, Duong DM, Wesseling H, Kundinger SR, Wang K, Williams D, DeTure M, Dickson DW, Cook CN, Seyfried NT, Petrucelli L, Steen JA, Fitzpatrick AWP. Arakhamia T, et al. Cell. 2021 Dec 9;184(25):6207-6210. doi: 10.1016/j.cell.2021.11.029. Cell. 2021. PMID: 34890553 Free PMC article. No abstract available.