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Page 1
Inhibition of azoxymethane-induced rat colon carcinogenesis by potassium hydrogen D-glucarate.
Yoshimi N, Walaszek Z, Mori H, Hanausek M, Szemraj J, Slaga TJ. Yoshimi N, et al. Int J Oncol. 2000 Jan;16(1):43-8. doi: 10.3892/ijo.16.1.43. Int J Oncol. 2000. PMID: 10601547
While calcium D-glucarate was shown to inhibit chemical carcinogenesis in various animal models, the effect of potassium hydrogen D-glucarate has not been extensively investigated. ...Potassium hydrogen D-glucarate (PHG) or potassium hydr …
While calcium D-glucarate was shown to inhibit chemical carcinogenesis in various animal models, the effect of potassium hydro …
Identification and characterization of two new 5-keto-4-deoxy-D-Glucarate Dehydratases/Decarboxylases.
Pick A, Beer B, Hemmi R, Momma R, Schmid J, Miyamoto K, Sieber V. Pick A, et al. BMC Biotechnol. 2016 Nov 17;16(1):80. doi: 10.1186/s12896-016-0308-3. BMC Biotechnol. 2016. PMID: 27855668 Free PMC article.
One representative, the oxidative pathway, generates alpha-keto-glutarate as the direct link entering towards the citric acid cycle. The penultimate enzyme, keto-deoxy glucarate dehydratase/decarboxylase, catalyses the dehydration and decarboxylation of keto-deoxy gluca …
One representative, the oxidative pathway, generates alpha-keto-glutarate as the direct link entering towards the citric acid cycle. The pen …
Accumulation of technetium-99m glucarate: in vitro cell cultures and in vivo tumour models.
Ballinger JR, Hsue V, Rauth AM. Ballinger JR, et al. Nucl Med Commun. 2003 May;24(5):597-606. doi: 10.1097/00006231-200305000-00017. Nucl Med Commun. 2003. PMID: 12717079
99mTc-glucarate is an investigational radiopharmaceutical which has been shown to accumulate in acute cerebral and myocardial injuries and in some tumours. ...At temperatures lower than 37 degrees C, accumulation was reduced, but a hypoxic/aerobic differential was maintain …
99mTc-glucarate is an investigational radiopharmaceutical which has been shown to accumulate in acute cerebral and myocardial injurie …
Selective glucose electro-oxidation catalyzed by TEMPO on graphite felt.
Ginoux E, Rafaïdeen T, Cognet P, Latapie L, Coutanceau C. Ginoux E, et al. Front Chem. 2024 May 1;12:1393860. doi: 10.3389/fchem.2024.1393860. eCollection 2024. Front Chem. 2024. PMID: 38752198 Free PMC article.
Long-term electrolyses of glucose in a potassium carbonate (K(2)CO(3)) aqueous electrolyte have been performed on graphite felt electrodes with TEMPO as a homogeneous catalyst. ...Side products such as glucaric acid were also obtained when the applied potential exce …
Long-term electrolyses of glucose in a potassium carbonate (K(2)CO(3)) aqueous electrolyte have been performed on graphite felt elect …
[Anticarcinogenic effect of potassium salts of glucaric and glucuronic acid in induced models of cervical and esophageal tumors].
Bespalov VG, Aleksandrov VA. Bespalov VG, et al. Vopr Onkol. 2012;58(4):537-40. Vopr Onkol. 2012. PMID: 23607211 Russian.
This study compares the anti-carcinogenic activity of calcium glucarate, potassium glucarate, and potassium glucuronate in cervix and esophagus induced cancer murine models. ...Compared with calcium glucarate, potassium salts of glucar …
This study compares the anti-carcinogenic activity of calcium glucarate, potassium glucarate, and potassium gluc …
Glucaric Acid Production from Miscanthus sacchariflorus via TEMPO-Mediated Oxidation with an Efficient Separation System.
Kim J, Kim D, Yoon H, Shin JH, Park S, Kwak HW, Ahn MR, Koo B, Choi IG. Kim J, et al. ACS Omega. 2024 Feb 16;9(8):9432-9442. doi: 10.1021/acsomega.3c08924. eCollection 2024 Feb 27. ACS Omega. 2024. PMID: 38434861 Free PMC article.
In this study, production and isolation of glucaric acid from lignocellulosic biomass were performed via potassium cation-based TEMPO-mediated oxidation for the ease of glucaric acid isolation. ...As a result, more oxidant was required to produce sufficient …
In this study, production and isolation of glucaric acid from lignocellulosic biomass were performed via potassium cation-base …
Mechanistic Understanding of D-Glucaric Acid to Support Liver Detoxification Essential to Muscle Health Using a Computational Systems Biology Approach.
Ayyadurai VAS, Deonikar P, Fields C. Ayyadurai VAS, et al. Nutrients. 2023 Feb 1;15(3):733. doi: 10.3390/nu15030733. Nutrients. 2023. PMID: 36771439 Free PMC article.
Computational-in silico-molecular systems' biology analysis of supplementation of calcium and potassium glucarate salts and their metabolite D-glucaric acid (GA) reveals their positive effect on mitigation of liver detoxification via four specific molecular p …
Computational-in silico-molecular systems' biology analysis of supplementation of calcium and potassium glucarate salts and th …
Metabolism, uptake, and excretion of a D-glucaric acid salt and its potential use in cancer prevention.
Walaszek Z, Szemraj J, Narog M, Adams AK, Kilgore J, Sherman U, Hanausek M. Walaszek Z, et al. Cancer Detect Prev. 1997;21(2):178-90. Cancer Detect Prev. 1997. PMID: 9101079
D-Glucaric acid (GA) is a nontoxic, natural compound. One of its derivatives is the potent beta-glucuronidase inhibitor D-glucaro-1,4-lactone (1,4-GL). The goal of this study was to demonstrate the in vivo formation of 1,4-GL from a D-glucarate salt and determine it …
D-Glucaric acid (GA) is a nontoxic, natural compound. One of its derivatives is the potent beta-glucuronidase inhibitor D-glucaro-1,4 …
Klotho sensitivity of the hERG channel.
Munoz C, Pakladok T, Almilaji A, Elvira B, Seebohm G, Voelkl J, Föller M, Shumilina E, Lang F. Munoz C, et al. FEBS Lett. 2013 Jun 5;587(11):1663-8. doi: 10.1016/j.febslet.2013.04.011. Epub 2013 Apr 18. FEBS Lett. 2013. PMID: 23603386
20 results