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Histological reappraisal of IgA nephropathy: the role of glomerular pattern of injury and mesangial complement deposition.
Obrișcă B, Mocanu V, Jurubiță R, Vrabie A, Berechet A, Lujinschi Ș, Sorohan B, Andronesi A, Achim C, Lupușoru G, Micu G, Caceaune N, Gherghiceanu M, Ismail G. Obrișcă B, et al. BMC Nephrol. 2024 Apr 24;25(1):145. doi: 10.1186/s12882-024-03577-z. BMC Nephrol. 2024. PMID: 38658875
The LM pattern of glomerular injury was reevaluated based on a modified HAAS classification. Mesangial C3 deposition by immunofluorescence (IF) staining was scored semi-quantitatively. ...Regarding the IF findings, mild-moderate and intense mesangial C3 staining was …
The LM pattern of glomerular injury was reevaluated based on a modified HAAS classification. Mesangial C3 deposition by immunofluores …
Seco-cyclic phorbol derivatives and their anti-HIV-1 activities.
Huang X, Huang X, Li Q, Ma M, Cui Y, Yang L, Wang H, Luo R, Chen J, Yang J, Lin J, Li D, Zheng Y, Zhang J. Huang X, et al. Chin J Nat Med. 2024 Apr;22(4):365-374. doi: 10.1016/S1875-5364(24)60630-8. Chin J Nat Med. 2024. PMID: 38658099
The efficacy of phorbol esters in binding with PKC is attributed to the presence of oxygen groups at positions C20, C3/C4, and C9 of phorbol. Concurrently, the lipids located at positions C12/C13 are essential for both the anti-HIV-1 activity and the formation of the PKC-l …
The efficacy of phorbol esters in binding with PKC is attributed to the presence of oxygen groups at positions C20, C3/C4, and C9 of …
Molecular mechanism of complement inhibition by the trypanosome receptor ISG65.
Cook AD, Carrington M, Higgins MK. Cook AD, et al. Elife. 2024 Apr 24;12:RP88960. doi: 10.7554/eLife.88960. Elife. 2024. PMID: 38655765
African trypanosomes replicate within infected mammals where they are exposed to the complement system. This system centres around complement C3, which is present in a soluble form in serum but becomes covalently deposited onto the surfaces of pathogens after proteolytic c …
African trypanosomes replicate within infected mammals where they are exposed to the complement system. This system centres around complemen …
89,234 results
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