Poulin P - Search Results

1

Utility of physiologically based pharmacokinetic models to drug development and rational drug discovery candidate selection.

Theil FP, Guentert TW, Haddad S, Poulin P. Theil FP, et al. Among authors: poulin p. Toxicol Lett. 2003 Feb 18;138(1-2):29-49. doi: 10.1016/s0378-4274(02)00374-0. Toxicol Lett. 2003. PMID: 12559691 Review.

2

Dose selection based on physiologically based pharmacokinetic (PBPK) approaches.

Jones HM, Mayawala K, Poulin P. Jones HM, et al. Among authors: poulin p. AAPS J. 2013 Apr;15(2):377-87. doi: 10.1208/s12248-012-9446-2. Epub 2012 Dec 27. AAPS J. 2013. PMID: 23269526 Free PMC article. Review.

3

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: comparative assessement of prediction methods of human clearance.

Ring BJ, Chien JY, Adkison KK, Jones HM, Rowland M, Jones RD, Yates JW, Ku MS, Gibson CR, He H, Vuppugalla R, Marathe P, Fischer V, Dutta S, Sinha VK, Björnsson T, Lavé T, Poulin P. Ring BJ, et al. Among authors: poulin p. J Pharm Sci. 2011 Oct;100(10):4090-110. doi: 10.1002/jps.22552. Epub 2011 May 3. J Pharm Sci. 2011. PMID: 21541938

4

PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: prediction of plasma concentration-time profiles in human by using the physiologically-based pharmacokinetic modeling approach.

Poulin P, Jones RD, Jones HM, Gibson CR, Rowland M, Chien JY, Ring BJ, Adkison KK, Ku MS, He H, Vuppugalla R, Marathe P, Fischer V, Dutta S, Sinha VK, Björnsson T, Lavé T, Yates JW. Poulin P, et al. J Pharm Sci. 2011 Oct;100(10):4127-57. doi: 10.1002/jps.22550. Epub 2011 May 3. J Pharm Sci. 2011. PMID: 21541937

5

Physiologically based pharmacokinetic (PBPK) modeling of disposition of epiroprim in humans.

Luttringer O, Theil FP, Poulin P, Schmitt-Hoffmann AH, Guentert TW, Lavé T. Luttringer O, et al. Among authors: poulin p. J Pharm Sci. 2003 Oct;92(10):1990-2007. doi: 10.1002/jps.10461. J Pharm Sci. 2003. PMID: 14502539

6

Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution.

Poulin P, Theil FP. Poulin P, et al. J Pharm Sci. 2002 Jan;91(1):129-56. doi: 10.1002/jps.10005. J Pharm Sci. 2002. PMID: 11782904

7

Prediction of pharmacokinetics prior to in vivo studies. II. Generic physiologically based pharmacokinetic models of drug disposition.

Poulin P, Theil FP. Poulin P, et al. J Pharm Sci. 2002 May;91(5):1358-70. doi: 10.1002/jps.10128. J Pharm Sci. 2002. PMID: 11977112

8

Molecular structure-based prediction of human abdominal skin permeability coefficients for several organic compounds.

Poulin P, Krishnan K. Poulin P, et al. J Toxicol Environ Health A. 2001 Feb 9;62(3):143-59. doi: 10.1080/009841001458271. J Toxicol Environ Health A. 2001. PMID: 11212942

9

Prediction of adipose tissue: plasma partition coefficients for structurally unrelated drugs.

Poulin P, Schoenlein K, Theil FP. Poulin P, et al. J Pharm Sci. 2001 Apr;90(4):436-47. doi: 10.1002/1520-6017(200104)90:4<436::aid-jps1002>3.0.co;2-p. J Pharm Sci. 2001. PMID: 11170034

10

A priori prediction of tissue:plasma partition coefficients of drugs to facilitate the use of physiologically-based pharmacokinetic models in drug discovery.

Poulin P, Theil FP. Poulin P, et al. J Pharm Sci. 2000 Jan;89(1):16-35. doi: 10.1002/(SICI)1520-6017(200001)89:1<16::AID-JPS3>3.0.CO;2-E. J Pharm Sci. 2000. PMID: 10664535

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