Poulsen ET - Search Results

1

Mutation-Induced Deamidation of Corneal Dystrophy-Related Transforming Growth Factor β-Induced Protein.

Nielsen NS, Juhl DW, Poulsen ET, Lukassen MV, Poulsen EC, Risør MW, Scavenius C, Enghild JJ. Nielsen NS, et al. Among authors: poulsen et, poulsen ec. Biochemistry. 2017 Dec 12;56(49):6470-6480. doi: 10.1021/acs.biochem.7b00668. Epub 2017 Nov 22. Biochemistry. 2017. PMID: 29140698

2

Comparison of two phenotypically distinct lattice corneal dystrophies caused by mutations in the transforming growth factor beta induced (TGFBI) gene.

Poulsen ET, Runager K, Risør MW, Dyrlund TF, Scavenius C, Karring H, Praetorius J, Vorum H, Otzen DE, Klintworth GK, Enghild JJ. Poulsen ET, et al. Proteomics Clin Appl. 2014 Apr;8(3-4):168-77. doi: 10.1002/prca.201300058. Epub 2014 Feb 16. Proteomics Clin Appl. 2014. PMID: 24302499 Free PMC article.

3

The autolysis of human HtrA1 is governed by the redox state of its N-terminal domain.

Risør MW, Poulsen ET, Thomsen LR, Dyrlund TF, Nielsen TA, Nielsen NC, Sanggaard KW, Enghild JJ. Risør MW, et al. Among authors: poulsen et. Biochemistry. 2014 Jun 17;53(23):3851-7. doi: 10.1021/bi401633w. Epub 2014 Jun 6. Biochemistry. 2014. PMID: 24846539 Free PMC article.

4

LASIK surgery of granular corneal dystrophy type 2 patients leads to accumulation and differential proteolytic processing of transforming growth factor beta-induced protein (TGFBIp).

Poulsen ET, Nielsen NS, Jensen MM, Nielsen E, Hjortdal J, Kim EK, Enghild JJ. Poulsen ET, et al. Proteomics. 2016 Feb;16(3):539-43. doi: 10.1002/pmic.201500287. Epub 2016 Jan 3. Proteomics. 2016. PMID: 26864644

5

Proteomic profiling of TGFBI-null mouse corneas reveals only minor changes in matrix composition supportive of TGFBI knockdown as therapy against TGFBI-linked corneal dystrophies.

Poulsen ET, Runager K, Nielsen NS, Lukassen MV, Thomsen K, Snider P, Simmons O, Vorum H, Conway SJ, Enghild JJ. Poulsen ET, et al. FEBS J. 2018 Jan;285(1):101-114. doi: 10.1111/febs.14321. Epub 2017 Nov 23. FEBS J. 2018. PMID: 29117645 Free PMC article.

6

The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation.

Poulsen ET, Nielsen NS, Scavenius C, Mogensen EH, Risør MW, Runager K, Lukassen MV, Rasmussen CB, Christiansen G, Richner M, Vorum H, Enghild JJ. Poulsen ET, et al. J Biol Chem. 2019 Aug 2;294(31):11817-11828. doi: 10.1074/jbc.RA119.009050. Epub 2019 Jun 13. J Biol Chem. 2019. PMID: 31197037 Free PMC article.

7

Biochemical mechanisms of aggregation in TGFBI-linked corneal dystrophies.

Nielsen NS, Poulsen ET, Lukassen MV, Chao Shern C, Mogensen EH, Weberskov CE, DeDionisio L, Schauser L, Moore TCB, Otzen DE, Hjortdal J, Enghild JJ. Nielsen NS, et al. Among authors: poulsen et. Prog Retin Eye Res. 2020 Jul;77:100843. doi: 10.1016/j.preteyeres.2020.100843. Epub 2020 Jan 29. Prog Retin Eye Res. 2020. PMID: 32004730 Review.

8

Mutation-induced dimerization of transforming growth factor-β-induced protein may drive protein aggregation in granular corneal dystrophy.

Nielsen NS, Gadeberg TAF, Poulsen ET, Harwood SL, Weberskov CE, Pedersen JS, Andersen GR, Enghild JJ. Nielsen NS, et al. Among authors: poulsen et. J Biol Chem. 2021 Jul;297(1):100858. doi: 10.1016/j.jbc.2021.100858. Epub 2021 Jun 4. J Biol Chem. 2021. PMID: 34097874 Free PMC article.

9

Structural and Functional Implications of Human Transforming Growth Factor β-Induced Protein, TGFBIp, in Corneal Dystrophies.

García-Castellanos R, Nielsen NS, Runager K, Thøgersen IB, Lukassen MV, Poulsen ET, Goulas T, Enghild JJ, Gomis-Rüth FX. García-Castellanos R, et al. Among authors: poulsen et. Structure. 2017 Nov 7;25(11):1740-1750.e2. doi: 10.1016/j.str.2017.09.001. Epub 2017 Oct 5. Structure. 2017. PMID: 28988748 Free article.

10

Protein Analysis of the TGFBI^R124H Mouse Model Gives Insight into Phenotype Development of Granular Corneal Dystrophy.

Lukassen MV, Poulsen ET, Donaghy J, Mogensen EH, Christie KA, Roshanravan H, DeDioniso L, Nesbit MA, Moore T, Enghild JJ. Lukassen MV, et al. Among authors: poulsen et. Proteomics Clin Appl. 2020 Nov;14(6):e1900072. doi: 10.1002/prca.201900072. Epub 2020 Jul 6. Proteomics Clin Appl. 2020. PMID: 32558206

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