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VEGF-C sustains VEGFR2 activation under bevacizumab therapy and promotes glioblastoma maintenance.
Michaelsen SR, Staberg M, Pedersen H, Jensen KE, Majewski W, Broholm H, Nedergaard MK, Meulengracht C, Urup T, Villingshøj M, Lukacova S, Skjøth-Rasmussen J, Brennum J, Kjær A, Lassen U, Stockhausen MT, Poulsen HS, Hamerlik P. Michaelsen SR, et al. Neuro Oncol. 2018 Oct 9;20(11):1462-1474. doi: 10.1093/neuonc/noy103. Neuro Oncol. 2018. PMID: 29939339 Free PMC article.
The use of longitudinal 18F-FET MicroPET imaging to evaluate response to irinotecan in orthotopic human glioblastoma multiforme xenografts.
Nedergaard MK, Kristoffersen K, Michaelsen SR, Madsen J, Poulsen HS, Stockhausen MT, Lassen U, Kjaer A. Nedergaard MK, et al. PLoS One. 2014 Jun 11;9(2):e100009. doi: 10.1371/journal.pone.0100009. eCollection 2014. PLoS One. 2014. PMID: 24918622 Free PMC article.
Single agent- and combination treatment with two targeted suicide gene therapy systems is effective in chemoresistant small cell lung cancer cells.
Michaelsen SR, Christensen CL, Sehested M, Cramer F, Poulsen TT, Patterson AV, Poulsen HS. Michaelsen SR, et al. J Gene Med. 2012 Jul;14(7):445-58. doi: 10.1002/jgm.2630. J Gene Med. 2012. PMID: 22576955
Targeting the epidermal growth factor receptor in solid tumor malignancies.
Nedergaard MK, Hedegaard CJ, Poulsen HS. Nedergaard MK, et al. BioDrugs. 2012 Apr 1;26(2):83-99. doi: 10.2165/11599760-000000000-00000. BioDrugs. 2012. PMID: 22385404 Review.
EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes.
Grandal MV, Zandi R, Pedersen MW, Willumsen BM, van Deurs B, Poulsen HS. Grandal MV, et al. Carcinogenesis. 2007 Jul;28(7):1408-17. doi: 10.1093/carcin/bgm058. Epub 2007 Mar 19. Carcinogenesis. 2007. PMID: 17372273
Analysis of the epidermal growth factor receptor specific transcriptome: effect of receptor expression level and an activating mutation.
Pedersen MW, Pedersen N, Damstrup L, Villingshøj M, Sønder SU, Rieneck K, Bovin LF, Spang-Thomsen M, Poulsen HS. Pedersen MW, et al. J Cell Biochem. 2005 Oct 1;96(2):412-27. doi: 10.1002/jcb.20554. J Cell Biochem. 2005. PMID: 16075456
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