Poulsen TB - Search Results

1

The amido-pentadienoate-functionality of the rakicidins is a thiol reactive electrophile--development of a general synthetic strategy.

Clement LL, Tsakos M, Schaffert ES, Scavenius C, Enghild JJ, Poulsen TB. Clement LL, et al. Among authors: poulsen tb. Chem Commun (Camb). 2015 Aug 11;51(62):12427-30. doi: 10.1039/c5cc04500b. Chem Commun (Camb). 2015. PMID: 26146360

2

A concise route to the macrocyclic core of the rakicidins.

Poulsen TB. Poulsen TB. Chem Commun (Camb). 2011 Dec 28;47(48):12837-9. doi: 10.1039/c1cc15829e. Epub 2011 Nov 2. Chem Commun (Camb). 2011. PMID: 22045383

3

Ester coupling reactions--an enduring challenge in the chemical synthesis of bioactive natural products.

Tsakos M, Schaffert ES, Clement LL, Villadsen NL, Poulsen TB. Tsakos M, et al. Among authors: poulsen tb. Nat Prod Rep. 2015 Apr;32(4):605-32. doi: 10.1039/c4np00106k. Nat Prod Rep. 2015. PMID: 25572105 Review.

4

The natural product brartemicin is a high affinity ligand for the carbohydrate-recognition domain of the macrophage receptor mincle.

Jacobsen KM, Keiding UB, Clement LL, Schaffert ES, Rambaruth ND, Johannsen M, Drickamer K, Poulsen TB. Jacobsen KM, et al. Among authors: poulsen tb. Medchemcomm. 2015 Apr 10;6(4):647-652. doi: 10.1039/c4md00512k. Epub 2015 Jan 7. Medchemcomm. 2015. PMID: 25893085 Free PMC article.

5

Total Synthesis and Biological Evaluation of Rakicidin A and Discovery of a Simplified Bioactive Analogue.

Tsakos M, Clement LL, Schaffert ES, Olsen FN, Rupiani S, Djurhuus R, Yu W, Jacobsen KM, Villadsen NL, Poulsen TB. Tsakos M, et al. Among authors: poulsen tb. Angew Chem Int Ed Engl. 2016 Jan 18;55(3):1030-5. doi: 10.1002/anie.201509926. Epub 2015 Dec 4. Angew Chem Int Ed Engl. 2016. PMID: 26637117

6

Synthesis of ent-BE-43547A₁ reveals a potent hypoxia-selective anticancer agent and uncovers the biosynthetic origin of the APD-CLD natural products.

Villadsen NL, Jacobsen KM, Keiding UB, Weibel ET, Christiansen B, Vosegaard T, Bjerring M, Jensen F, Johannsen M, Tørring T, Poulsen TB. Villadsen NL, et al. Among authors: poulsen tb. Nat Chem. 2017 Mar;9(3):264-272. doi: 10.1038/nchem.2657. Epub 2016 Nov 21. Nat Chem. 2017. PMID: 28221346

7

APD-Containing Cyclolipodepsipeptides Target Mitochondrial Function in Hypoxic Cancer Cells.

Jacobsen KM, Villadsen NL, Tørring T, Nielsen CB, Salomón T, Nielsen MM, Tsakos M, Sibbersen C, Scavenius C, Nielsen R, Christensen EI, Guerra PF, Bross P, Pedersen JS, Enghild JJ, Johannsen M, Frøkiær J, Overgaard J, Horsman MR, Busk M, Poulsen TB. Jacobsen KM, et al. Among authors: poulsen tb. Cell Chem Biol. 2018 Nov 15;25(11):1337-1349.e12. doi: 10.1016/j.chembiol.2018.07.010. Epub 2018 Aug 16. Cell Chem Biol. 2018. PMID: 30122371 Free article.

8

Total Synthesis of Natural Products Containing Enamine or Enol Ether Derivatives.

Poulsen TB. Poulsen TB. Acc Chem Res. 2021 Apr 20;54(8):1830-1842. doi: 10.1021/acs.accounts.0c00851. Epub 2021 Mar 4. Acc Chem Res. 2021. PMID: 33660974

9

Enantioselective organocatalytic allylic amination.

Poulsen TB, Alemparte C, Jørgensen KA. Poulsen TB, et al. J Am Chem Soc. 2005 Aug 24;127(33):11614-5. doi: 10.1021/ja0539847. J Am Chem Soc. 2005. PMID: 16104733

10

Enantioselective organocatalytic substitution of alpha-cyanoacetates on imidoyl chlorides--synthesis of optically active ketimines.

Santoro S, Poulsen TB, Jørgensen KA. Santoro S, et al. Among authors: poulsen tb. Chem Commun (Camb). 2007 Dec 28;(48):5155-7. doi: 10.1039/b715810f. Epub 2007 Nov 16. Chem Commun (Camb). 2007. PMID: 18060126

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