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Year Number of Results
1982 1
1992 2
1993 1
1998 2
2000 5
2001 2
2002 1
2003 1
2004 2
2006 2
2007 2
2013 2
2014 3
2015 2
2016 2
2017 2
2018 1
2019 1
2020 1
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32 results
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Cognitive function and mood at high altitude following acclimatization and use of supplemental oxygen and adaptive servoventilation sleep treatments.
Heinrich EC, Djokic MA, Gilbertson D, DeYoung PN, Bosompra NO, Wu L, Anza-Ramirez C, Orr JE, Powell FL, Malhotra A, Simonson TS. Heinrich EC, et al. Among authors: Powell FL. PLoS One. 2019 Jun 12;14(6):e0217089. doi: 10.1371/journal.pone.0217089. eCollection 2019. PLoS One. 2019. PMID: 31188839 Free PMC article.
Impairments in cognitive function, mood, and sleep quality occur following ascent to high altitude. Low oxygen (hypoxia) and poor sleep quality are both linked to impaired cognitive performance, but their independent contributions at high altitude remain unknown. .. …
Impairments in cognitive function, mood, and sleep quality occur following ascent to high altitude. Low oxygen (hypoxia) and poor sle …
Adaptive Servoventilation as Treatment for Central Sleep Apnea Due to High-Altitude Periodic Breathing in Nonacclimatized Healthy Individuals.
Orr JE, Heinrich EC, Djokic M, Gilbertson D, Deyoung PN, Anza-Ramirez C, Villafuerte FC, Powell FL, Malhotra A, Simonson T. Orr JE, et al. Among authors: Powell FL. High Alt Med Biol. 2018 Jun;19(2):178-184. doi: 10.1089/ham.2017.0147. Epub 2018 Mar 13. High Alt Med Biol. 2018. PMID: 29641294 Free PMC article. Clinical Trial.
AIMS: Central sleep apnea (CSA) is common at high altitude, leading to desaturation and sleep disruption. We hypothesized that noninvasive ventilation using adaptive servoventilation (ASV) would be effective at stabilizing CSA at altitude. ...ASV may have utility in …
AIMS: Central sleep apnea (CSA) is common at high altitude, leading to desaturation and sleep disruption. We hypothesized that noninv …
The impact of inflammation on respiratory plasticity.
Hocker AD, Stokes JA, Powell FL, Huxtable AG. Hocker AD, et al. Among authors: Powell FL. Exp Neurol. 2017 Jan;287(Pt 2):243-253. doi: 10.1016/j.expneurol.2016.07.022. Epub 2016 Jul 27. Exp Neurol. 2017. PMID: 27476100 Free PMC article. Review.
Here, we review some of common models used to investigate the effects of inflammation and discuss the impact of inflammation on nociception, chemosensory plasticity, medullary respiratory centers, motor plasticity in motor neurons and respiratory frequency, and adaptation to high …
Here, we review some of common models used to investigate the effects of inflammation and discuss the impact of inflammation on nociception, …
Evidence from high-altitude acclimatization for an integrated cerebrovascular and ventilatory hypercapnic response but different responses to hypoxia.
Smith ZM, Krizay E, Sá RC, Li ET, Scadeng M, Powell FL Jr, Dubowitz DJ. Smith ZM, et al. Among authors: Powell FL. J Appl Physiol (1985). 2017 Dec 1;123(6):1477-1486. doi: 10.1152/japplphysiol.00341.2017. Epub 2017 Jul 13. J Appl Physiol (1985). 2017. PMID: 28705997 Free PMC article.
Measurements were repeated after 2 days of acclimatization to hypoxia at 3,800 m altitude (partial pressure of inspired O(2) = 90 Torr) to compare plasticity in the chemosensitivity of these two systems. ...
Measurements were repeated after 2 days of acclimatization to hypoxia at 3,800 m altitude (partial pressure of inspired O(2) = 90 Tor …
Ibuprofen Blunts Ventilatory Acclimatization to Sustained Hypoxia in Humans.
Basaran KE, Villongco M, Ho B, Ellis E, Zarndt R, Antonova J, Hopkins SR, Powell FL. Basaran KE, et al. Among authors: Powell FL. PLoS One. 2016 Jan 4;11(1):e0146087. doi: 10.1371/journal.pone.0146087. eCollection 2016. PLoS One. 2016. PMID: 26726885 Free PMC article. Clinical Trial.
Ibuprofen significantly decreased the HVR after acclimatization to high altitude compared to placebo but it did not affect ventilation or arterial O2 saturation breathing ambient air at high altitude. Hence, compensatory responses prevent hypoventilation with decrea …
Ibuprofen significantly decreased the HVR after acclimatization to high altitude compared to placebo but it did not affect ventilatio …
Physiological effects of intermittent hypoxia.
Powell FL, Garcia N. Powell FL, et al. High Alt Med Biol. 2000 Summer;1(2):125-36. doi: 10.1089/15270290050074279. High Alt Med Biol. 2000. PMID: 11256564 Review.
IH for high altitude workers who commute from low altitude homes is of considerable practical interest and the ideal commuting schedule for physical and mental performance is being studied. The effect of oxygen enrichment at altitude (i.e., intermittent normo …
IH for high altitude workers who commute from low altitude homes is of considerable practical interest and the ideal commuting …
Role of chemoreception in cardiorespiratory acclimatization to, and deacclimatization from, hypoxia.
Dempsey JA, Powell FL, Bisgard GE, Blain GM, Poulin MJ, Smith CA. Dempsey JA, et al. Among authors: Powell FL. J Appl Physiol (1985). 2014 Apr 1;116(7):858-66. doi: 10.1152/japplphysiol.01126.2013. Epub 2013 Dec 26. J Appl Physiol (1985). 2014. PMID: 24371017 Free PMC article. Review.
During sojourn to high altitudes, progressive time-dependent increases occur in ventilation and in sympathetic nerve activity over several days, and these increases persist upon acute restoration of normoxia. ...
During sojourn to high altitudes, progressive time-dependent increases occur in ventilation and in sympathetic nerve activity over se …
Cardiac responses to hypoxia and reoxygenation in Drosophila.
Zarndt R, Piloto S, Powell FL, Haddad GG, Bodmer R, Ocorr K. Zarndt R, et al. Among authors: Powell FL. Am J Physiol Regul Integr Comp Physiol. 2015 Dec 1;309(11):R1347-57. doi: 10.1152/ajpregu.00164.2015. Epub 2015 Sep 16. Am J Physiol Regul Integr Comp Physiol. 2015. PMID: 26377557 Free PMC article.
Insufficient tissue oxygenation occurs under a variety of conditions, including high altitude, embryonic and fetal development, inflammation, and thrombotic diseases, often affecting multiple organ systems. ...
Insufficient tissue oxygenation occurs under a variety of conditions, including high altitude, embryonic and fetal development, infla …
Less is more: blunted responses to hypoxia revealed in sea-level Tibetans.
Simonson TS, Powell FL. Simonson TS, et al. Among authors: Powell FL. J Appl Physiol (1985). 2014 Apr 1;116(7):711-2. doi: 10.1152/japplphysiol.01110.2013. Epub 2013 Oct 10. J Appl Physiol (1985). 2014. PMID: 24114703 Free article. No abstract available.
Time domains of the hypoxic ventilatory response.
Powell FL, Milsom WK, Mitchell GS. Powell FL, et al. Respir Physiol. 1998 May;112(2):123-34. doi: 10.1016/s0034-5687(98)00026-7. Respir Physiol. 1998. PMID: 9716296 Review.
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