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Synthesis and evaluation of 4-anilino-6,7-dialkoxy-3-quinolinecarbonitriles as inhibitors of kinases of the Ras-MAPK signaling cascade.
Berger D, Dutia M, Powell D, Wu B, Wissner A, Boschelli DH, Floyd MB, Zhang N, Torres N, Levin J, Du X, Wojciechowicz D, Discafani C, Kohler C, Kim SC, Feldberg LR, Collins K, Mallon R. Berger D, et al. Among authors: powell d. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3031-4. doi: 10.1016/s0960-894x(03)00640-1. Bioorg Med Chem Lett. 2003. PMID: 12941327
4-Anilino-7-alkenylquinoline-3-carbonitriles as potent MEK1 kinase inhibitors.
Berger DM, Dutia M, Powell D, Floyd MB, Torres N, Mallon R, Wojciechowicz D, Kim S, Feldberg L, Collins K, Chaudhary I. Berger DM, et al. Among authors: powell d. Bioorg Med Chem. 2008 Oct 15;16(20):9202-11. doi: 10.1016/j.bmc.2008.09.009. Epub 2008 Sep 9. Bioorg Med Chem. 2008. PMID: 18815050
Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors.
Berger DM, Torres N, Dutia M, Powell D, Ciszewski G, Gopalsamy A, Levin JI, Kim KH, Xu W, Wilhelm J, Hu Y, Collins K, Feldberg L, Kim S, Frommer E, Wojciechowicz D, Mallon R. Berger DM, et al. Among authors: powell d. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6519-23. doi: 10.1016/j.bmcl.2009.10.049. Epub 2009 Oct 26. Bioorg Med Chem Lett. 2009. PMID: 19864136
4-Anilino-3-cyanobenzo[g]quinolines as kinase inhibitors.
Zhang N, Wu B, Wissner A, Powell DW, Rabindran SK, Kohler C, Boschelli F. Zhang N, et al. Bioorg Med Chem Lett. 2002 Feb 11;12(3):423-5. doi: 10.1016/s0960-894x(01)00776-4. Bioorg Med Chem Lett. 2002. PMID: 11814812
2,628 results