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2020 0
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Power of single- vs. multi-marker tests of association.
Wang X, Morris NJ, Schaid DJ, Elston RC. Wang X, et al. Genet Epidemiol. 2012 Jul;36(5):480-7. doi: 10.1002/gepi.21642. Epub 2012 May 30. Genet Epidemiol. 2012. PMID: 22648939 Free PMC article.
Current genome-wide association studies still heavily rely on a single-marker strategy, in which each single nucleotide polymorphism (SNP) is tested individually for association with a phenotype. ...The results reveal the power adv …
Current genome-wide association studies still heavily rely on a single-marker strategy, in which each single nuc …
GENOME-WIDE ASSOCIATION MAPPING AND RARE ALLELES: FROM POPULATION GENOMICS TO PERSONALIZED MEDICINE - Session Introduction.
DE LA Vega FM, Bustamante CD, Leal SM. DE LA Vega FM, et al. Pac Symp Biocomput. 2011:74-5. doi: 10.1142/9789814335058_0008. Pac Symp Biocomput. 2011. PMID: 21121034 Free PMC article.
Since single SNP tests are often underpowered in rare variant association analysis, Zeggini and Asimit propose a locus-based method that has high power in the presence of rare variants and that incorporate base quality scores available for sequencing d …
Since single SNP tests are often underpowered in rare variant association analysis, Zeggini and Asimit propose a locus- …
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