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Power of single- vs. multi-marker tests of association.
Wang X, Morris NJ, Schaid DJ, Elston RC. Wang X, et al. Genet Epidemiol. 2012 Jul;36(5):480-7. doi: 10.1002/gepi.21642. Epub 2012 May 30. Genet Epidemiol. 2012. PMID: 22648939 Free PMC article.
Based on conducting extensive simulations, here we endeavor to provide more insights into the performance of simple multimarker association tests as compared to single-marker tests. The results reveal the power advantage as well as disadv …
Based on conducting extensive simulations, here we endeavor to provide more insights into the performance of simple multimarker associati
GENOME-WIDE ASSOCIATION MAPPING AND RARE ALLELES: FROM POPULATION GENOMICS TO PERSONALIZED MEDICINE - Session Introduction.
DE LA Vega FM, Bustamante CD, Leal SM. DE LA Vega FM, et al. Pac Symp Biocomput. 2011:74-5. doi: 10.1142/9789814335058_0008. Pac Symp Biocomput. 2011. PMID: 21121034 Free PMC article.
These methods would allow testing haplotypes harboring rare variants for association and potentially increase their explanatory power. ...Their results suggest that this multi-marker approach may be best suited for smaller regions, or after some …
These methods would allow testing haplotypes harboring rare variants for association and potentially increase their explanator …