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Pathophysiological functions of cathepsin D: Targeting its catalytic activity versus its protein binding activity?

Masson O, Bach AS, Derocq D, Prébois C, Laurent-Matha V, Pattingre S, Liaudet-Coopman E. Masson O, et al. Among authors: prebois c. Biochimie. 2010 Nov;92(11):1635-43. doi: 10.1016/j.biochi.2010.05.009. Epub 2010 May 21. Biochimie. 2010. PMID: 20493920 Free article. Review.

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Processing of human cathepsin D is independent of its catalytic function and auto-activation: involvement of cathepsins L and B.

Laurent-Matha V, Derocq D, Prébois C, Katunuma N, Liaudet-Coopman E. Laurent-Matha V, et al. Among authors: prebois c. J Biochem. 2006 Mar;139(3):363-71. doi: 10.1093/jb/mvj037. J Biochem. 2006. PMID: 16567401 Free PMC article.

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Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment.

Laurent-Matha V, Huesgen PF, Masson O, Derocq D, Prébois C, Gary-Bobo M, Lecaille F, Rebière B, Meurice G, Oréar C, Hollingsworth RE, Abrahamson M, Lalmanach G, Overall CM, Liaudet-Coopman E. Laurent-Matha V, et al. Among authors: prebois c. FASEB J. 2012 Dec;26(12):5172-81. doi: 10.1096/fj.12-205229. Epub 2012 Aug 16. FASEB J. 2012. PMID: 22898924 Free article.

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Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesis.

Masson O, Prébois C, Derocq D, Meulle A, Dray C, Daviaud D, Quilliot D, Valet P, Muller C, Liaudet-Coopman E. Masson O, et al. Among authors: prebois c. PLoS One. 2011 Feb 2;6(2):e16452. doi: 10.1371/journal.pone.0016452. PLoS One. 2011. PMID: 21311773 Free PMC article.

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Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.

Beaujouin M, Prébois C, Derocq D, Laurent-Matha V, Masson O, Pattingre S, Coopman P, Bettache N, Grossfield J, Hollingsworth RE, Zhang H, Yao Z, Hyman BT, van der Geer P, Smith GK, Liaudet-Coopman E. Beaujouin M, et al. Among authors: prebois c. J Cell Sci. 2010 Oct 1;123(Pt 19):3336-46. doi: 10.1242/jcs.070938. Epub 2010 Sep 7. J Cell Sci. 2010. PMID: 20826454 Free PMC article.

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Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis.

Liaudet-Coopman E, Beaujouin M, Derocq D, Garcia M, Glondu-Lassis M, Laurent-Matha V, Prébois C, Rochefort H, Vignon F. Liaudet-Coopman E, et al. Among authors: prebois c. Cancer Lett. 2006 Jun 18;237(2):167-79. doi: 10.1016/j.canlet.2005.06.007. Epub 2005 Jul 19. Cancer Lett. 2006. PMID: 16046058 Review.

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Protein-tyrosine phosphatase PTPL1/FAP-1 triggers apoptosis in human breast cancer cells.

Bompard G, Puech C, Prébois C, Vignon F, Freiss G. Bompard G, et al. Among authors: prebois c. J Biol Chem. 2002 Dec 6;277(49):47861-9. doi: 10.1074/jbc.M208950200. Epub 2002 Sep 26. J Biol Chem. 2002. PMID: 12354757

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Catalytically inactive human cathepsin D triggers fibroblast invasive growth.

Laurent-Matha V, Maruani-Herrmann S, Prébois C, Beaujouin M, Glondu M, Noël A, Alvarez-Gonzalez ML, Blacher S, Coopman P, Baghdiguian S, Gilles C, Loncarek J, Freiss G, Vignon F, Liaudet-Coopman E. Laurent-Matha V, et al. Among authors: prebois c. J Cell Biol. 2005 Jan 31;168(3):489-99. doi: 10.1083/jcb.200403078. Epub 2005 Jan 24. J Cell Biol. 2005. PMID: 15668295 Free PMC article.

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BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy.

Sebti S, Prébois C, Pérez-Gracia E, Bauvy C, Desmots F, Pirot N, Gongora C, Bach AS, Hubberstey AV, Palissot V, Berchem G, Codogno P, Linares LK, Liaudet-Coopman E, Pattingre S. Sebti S, et al. Among authors: prebois c. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4115-20. doi: 10.1073/pnas.1313618111. Epub 2014 Mar 3. Proc Natl Acad Sci U S A. 2014. PMID: 24591579 Free PMC article.

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BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization.

Sebti S, Prébois C, Pérez-Gracia E, Bauvy C, Desmots F, Pirot N, Gongora C, Bach AS, Hubberstey AV, Palissot V, Berchem G, Codogno P, Linares LK, Liaudet-Coopman E, Pattingre S. Sebti S, et al. Among authors: prebois c. Autophagy. 2014 Jul;10(7):1341-2. doi: 10.4161/auto.28979. Epub 2014 May 15. Autophagy. 2014. PMID: 24852146 Free PMC article.

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