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Synthesis of [O-methyl-11C]1-(2-chlorophenyl)-5-(4-methoxyphenyl)-4-methyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide: a potential PET ligand for CB1 receptors.
Kumar JS, Prabhakaran J, Arango V, Parsey RV, Underwood MD, Simpson NR, Kassir SA, Majo VJ, Van Heertum RL, Mann JJ. Kumar JS, et al. Bioorg Med Chem Lett. 2004 May 17;14(10):2393-6. doi: 10.1016/j.bmcl.2004.03.034. Bioorg Med Chem Lett. 2004. PMID: 15109619
Synthesis and in vivo validation of [O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin- 1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione: a novel 5-HT1A receptor agonist positron emission tomography ligand.
Kumar JS, Majo VJ, Hsiung SC, Millak MS, Liu KP, Tamir H, Prabhakaran J, Simpson NR, Van Heertum RL, Mann JJ, Parsey RV. Kumar JS, et al. J Med Chem. 2006 Jan 12;49(1):125-34. doi: 10.1021/jm050725j. J Med Chem. 2006. PMID: 16392798
Synthesis, in vitro and in vivo evaluation of [O-methyl-11C] 2-{4-[4-(3-methoxyphenyl)piperazin-1-yl]-butyl}-4-methyl-2H-[1,2,4]-triazine-3,5-dione: a novel agonist 5-HT1A receptor PET ligand.
Prabhakaran J, Parsey RV, Majo VJ, Hsiung SC, Milak MS, Tamir H, Simpson NR, Van Heertum RL, Mann JJ, Dileep Kumar JS. Prabhakaran J, et al. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2101-4. doi: 10.1016/j.bmcl.2006.01.052. Epub 2006 Feb 3. Bioorg Med Chem Lett. 2006. PMID: 16458504
Synthesis and in vivo evaluation of [11C]SN003 as a PET ligand for CRF1 receptors.
Kumar JS, Majo VJ, Sullivan GM, Prabhakaran J, Simpson NR, Van Heertum RL, Mann JJ, Parsey RV. Kumar JS, et al. Bioorg Med Chem. 2006 Jun 15;14(12):4029-34. doi: 10.1016/j.bmc.2006.02.019. Epub 2006 Mar 10. Bioorg Med Chem. 2006. PMID: 16529935
Synthesis and in vivo evaluation of [O-methyl-11C](2R,4R)-4-hydroxy-2-[2-[2-[2-(3-methoxy)phenyl]ethyl]phenoxy]ethyl-1-methylpyrrolidine as a 5-HT2A receptor PET ligand.
Kumar JS, Prabhakaran J, Erlandsson K, Majo VJ, Simpson NR, Pratap M, Van Heertum RL, Mann JJ, Parsey RV. Kumar JS, et al. Nucl Med Biol. 2006 May;33(4):565-74. doi: 10.1016/j.nucmedbio.2006.02.001. Epub 2006 May 2. Nucl Med Biol. 2006. PMID: 16720250
Synthesis and in vivo evaluation of [18F]-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide as a PET imaging probe for COX-2 expression.
Prabhakaran J, Underwood MD, Parsey RV, Arango V, Majo VJ, Simpson NR, Van Heertum R, Mann JJ, Kumar JS. Prabhakaran J, et al. Bioorg Med Chem. 2007 Feb 15;15(4):1802-7. doi: 10.1016/j.bmc.2006.11.033. Epub 2006 Nov 29. Bioorg Med Chem. 2007. PMID: 17166726
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