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PCI-24781 induces caspase and reactive oxygen species-dependent apoptosis through NF-kappaB mechanisms and is synergistic with bortezomib in lymphoma cells.
Bhalla S, Balasubramanian S, David K, Sirisawad M, Buggy J, Mauro L, Prachand S, Miller R, Gordon LI, Evens AM. Bhalla S, et al. Among authors: prachand s. Clin Cancer Res. 2009 May 15;15(10):3354-65. doi: 10.1158/1078-0432.CCR-08-2365. Epub 2009 May 5. Clin Cancer Res. 2009. PMID: 19417023 Free PMC article.
Glutathione depletion enhances arsenic trioxide-induced apoptosis in lymphoma cells through mitochondrial-independent mechanisms.
Bhalla S, Gordon LI, David K, Prachand S, Singh AT, Yang S, Winter JN, Guo D, O'Halloran T, Platanias LC, Evens AM. Bhalla S, et al. Among authors: prachand s. Br J Haematol. 2010 Aug;150(3):365-9. doi: 10.1111/j.1365-2141.2010.08197.x. Epub 2010 Apr 16. Br J Haematol. 2010. PMID: 20408844 Free PMC article. No abstract available.
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