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Year Number of Results
1983 1
1984 1
1985 4
1986 4
1987 3
1988 1
1989 7
1990 2
1991 3
1992 2
1994 2
1995 3
1996 2
1998 1
1999 1
2003 1
2007 1
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2010 1
2012 1
2014 1
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43 results

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Page 1
Pharmacokinetics of oral pramiracetam in normal volunteers.
Chang T, Young RM, Goulet JR, Yakatan GJ. Chang T, et al. J Clin Pharmacol. 1985 May-Jun;25(4):291-5. doi: 10.1002/j.1552-4604.1985.tb02841.x. J Clin Pharmacol. 1985. PMID: 4008675 Clinical Trial.
The pharmacokinetics of pramiracetam, a new, investigational, cognition activator, were assessed in normal male volunteers as part of a clinical tolerance study. In a double-blind, randomized design, two groups of six subjects each received alternating placebo and single 4 …
The pharmacokinetics of pramiracetam, a new, investigational, cognition activator, were assessed in normal male volunteers as part of …
[Pharmacokinetics of pramiracetam in animals].
Fang Z, Liu X, Xiao Y, Jiang W. Fang Z, et al. Hua Xi Yi Ke Da Xue Xue Bao. 1999 Dec;30(4):411-3. Hua Xi Yi Ke Da Xue Xue Bao. 1999. PMID: 11387954 Chinese.
Pharmacokinetic rules of pramiracetam were studied here. After giving pramiracetam orally to dogs, we drew their blood at various times. ...The time-concentration curve corresponded to one apartment model. T1/2 was about 2.3-3.9 hours in various doses. After pram …
Pharmacokinetic rules of pramiracetam were studied here. After giving pramiracetam orally to dogs, we drew their blood at vari …
Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam.
Butler DE, Nordin IC, L'Italien YJ, Zweisler L, Poschel PH, Marriott JG. Butler DE, et al. J Med Chem. 1984 May;27(5):684-91. doi: 10.1021/jm00371a023. J Med Chem. 1984. PMID: 6716406
N-[2-[Bis(1-methylethyl)amino]ethyl] -2-oxo-1- pyrrolidineacetamide N-(dialkylamino) substituent was selected for preclinical toxicological evaluation, assigned the investigational number CI-879 and the U.S. adopted name ( USAN ) pramiracetam . Pramiracetam demonstr …
N-[2-[Bis(1-methylethyl)amino]ethyl] -2-oxo-1- pyrrolidineacetamide N-(dialkylamino) substituent was selected for preclinical toxicological …
The action of pramiracetam on consequences of hypobaric hypoxia is only moderate.
Maresová D, Mares P. Maresová D, et al. Physiol Res. 1996;45(3):245-8. Physiol Res. 1996. PMID: 9200217 Free article.
The possible protective action of pramiracetam, a pyrrolidinone nootropic drug, against hypobaric hypoxia was studied in two age groups of immature rats with implanted electrodes. ...The afterdischarges elicited by repeated stimulations (four times at 10 min intervals) did …
The possible protective action of pramiracetam, a pyrrolidinone nootropic drug, against hypobaric hypoxia was studied in two age grou …
Pramiracetam effects on scopolamine-induced amnesia in healthy volunteers.
Mauri M, Sinforiani E, Reverberi F, Merlo P, Bono G. Mauri M, et al. Arch Gerontol Geriatr. 1994 Mar-Apr;18(2):133-9. doi: 10.1016/0167-4943(94)00542-7. Arch Gerontol Geriatr. 1994. PMID: 15374306 Clinical Trial.
Pramiracetam has been evaluated for its potential antiamnesic properties in scopolamine-induced amnesia in healthy volunteers. Two groups of twelve males, 18-42 and 55-65 years old, respectively, were randomly assigned to oral treatment with pramiracetam (600 mg twi …
Pramiracetam has been evaluated for its potential antiamnesic properties in scopolamine-induced amnesia in healthy volunteers. Two gr …
Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders.
Malykh AG, Sadaie MR. Malykh AG, et al. Drugs. 2010 Feb 12;70(3):287-312. doi: 10.2165/11319230-000000000-00000. Drugs. 2010. PMID: 20166767 Review.
Subgroup 1 drugs include piracetam, oxiracetam, aniracetam, pramiracetam and phenylpiracetam, which have been used in humans and some of which are available as dietary supplements. Of these, oxiracetam and aniracetam are no longer in clinical use. Pramiracetam repor …
Subgroup 1 drugs include piracetam, oxiracetam, aniracetam, pramiracetam and phenylpiracetam, which have been used in humans and some …
The effect of pramiracetam (CI-879) on the acquisition of a radial arm maze task.
Murray CL, Fibiger HC. Murray CL, et al. Psychopharmacology (Berl). 1986;89(3):378-81. doi: 10.1007/BF00174378. Psychopharmacology (Berl). 1986. PMID: 3088666
The effect of the nootropic drug pramiracetam (CI-879) on acquisition of a radial arm maze task was examined in the rat. ...These data indicate that pramiracetam can enhance some aspects of spatial learning and memory in the rat....
The effect of the nootropic drug pramiracetam (CI-879) on acquisition of a radial arm maze task was examined in the rat. ...These dat …
Nootropic drugs and brain cholinergic mechanisms.
Pepeu G, Spignoli G. Pepeu G, et al. Prog Neuropsychopharmacol Biol Psychiatry. 1989;13 Suppl:S77-88. doi: 10.1016/0278-5846(89)90112-7. Prog Neuropsychopharmacol Biol Psychiatry. 1989. PMID: 2694231 Review.
Direct or indirect evidences indicating an activation of cholinergic mechanisms exist for pyrrolidinone derivatives including piracetam, oxiracetam, aniracetam, pyroglutamic acid, tenilsetam and pramiracetam and for miscellaneous chemical structures such as vinpocetine, na …
Direct or indirect evidences indicating an activation of cholinergic mechanisms exist for pyrrolidinone derivatives including piracetam, oxi …
Piracetam and other structurally related nootropics.
Gouliaev AH, Senning A. Gouliaev AH, et al. Brain Res Brain Res Rev. 1994 May;19(2):180-222. doi: 10.1016/0165-0173(94)90011-6. Brain Res Brain Res Rev. 1994. PMID: 8061686 Review.
This review covers clinical, pharmacokinetic, biochemical and behavioural results presented in the literature from 1965 through 1992 (407 references) of piracetam, oxiracetam, pramiracetam, etiracetam, nefiracetam, aniracetam and rolziracetam and their structural analogues …
This review covers clinical, pharmacokinetic, biochemical and behavioural results presented in the literature from 1965 through 1992 (407 re …
Placebo-controlled study of pramiracetam in young males with memory and cognitive problems resulting from head injury and anoxia.
McLean A Jr, Cardenas DD, Burgess D, Gamzu E. McLean A Jr, et al. Brain Inj. 1991 Oct-Dec;5(4):375-80. doi: 10.3109/02699059109008110. Brain Inj. 1991. PMID: 1786500 Clinical Trial.
The current study evaluated under double-blind placebo-controlled conditions, the safety and efficacy of 400 mg pramiracetam sulphate TID in treating memory and other cognitive problems of males who have sustained brain injuries. The results of the study indicate that subj …
The current study evaluated under double-blind placebo-controlled conditions, the safety and efficacy of 400 mg pramiracetam sulphate …
43 results