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Efflux pumps in drug resistance of Candida.
Prasad R, Gaur NA, Gaur M, Komath SS. Prasad R, et al. Infect Disord Drug Targets. 2006 Jun;6(2):69-83. doi: 10.2174/187152606784112164. Infect Disord Drug Targets. 2006. PMID: 16789872 Review.
CDR1, a multidrug resistance gene from Candida albicans, contains multiple regulatory domains in its promoter and the distal AP-1 element mediates its induction by miconazole.
Puri N, Krishnamurthy S, Habib S, Hasnain SE, Goswami SK, Prasad R. Puri N, et al. FEMS Microbiol Lett. 1999 Nov 15;180(2):213-9. doi: 10.1111/j.1574-6968.1999.tb08798.x. FEMS Microbiol Lett. 1999. PMID: 10556714
Asymmetric distribution of phosphatidylethanolamine in C. albicans: possible mediation by CDR1, a multidrug transporter belonging to ATP binding cassette (ABC) superfamily.
Dogra S, Krishnamurthy S, Gupta V, Dixit BL, Gupta CM, Sanglard D, Prasad R. Dogra S, et al. Yeast. 1999 Jan 30;15(2):111-21. doi: 10.1002/(SICI)1097-0061(19990130)15:2<111::AID-YEA350>3.0.CO;2-E. Yeast. 1999. PMID: 10029989
Identification of polymorphic mutant alleles of CaMDR1, a major facilitator of Candida albicans which confers multidrug resistance, and its in vitro transcriptional activation.
Gupta V, Kohli A, Krishnamurthy S, Puri N, Aalamgeer SA, Panwar S, Prasad R. Gupta V, et al. Curr Genet. 1998 Sep;34(3):192-9. doi: 10.1007/s002940050385. Curr Genet. 1998. PMID: 9745021
Deletion of transmembrane domain 12 of CDR1, a multidrug transporter from Candida albicans, leads to altered drug specificity: expression of a yeast multidrug transporter in baculovirus expression system.
Krishnamurthy S, Chatterjee U, Gupta V, Prasad R, Das P, Snehlata P, Hasnain SE, Prasad R. Krishnamurthy S, et al. Yeast. 1998 Apr 30;14(6):535-50. doi: 10.1002/(SICI)1097-0061(19980430)14:6<535::AID-YEA254>3.0.CO;2-5. Yeast. 1998. PMID: 9605504
Cdr1p, an ATP-binding cassette transporter from the pathogenic yeast Candida albicans, confers resistance to several unrelated drugs including anti-Candida drugs (Prasad et al., 1995b). ...
Cdr1p, an ATP-binding cassette transporter from the pathogenic yeast Candida albicans, confers resistance to several unrelated drugs includi …
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