Prashar V - Search Results

1

Crystallization and preliminary X-ray diffraction analysis of human seminal plasma protein PSP94.

Kumar M, Jagtap DD, Mahale SD, Prashar V, Kumar A, Das A, Bihani SC, Ferrer JL, Hosur MV, Ramanadham M. Kumar M, et al. Among authors: prashar v. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Apr 1;65(Pt 4):389-91. doi: 10.1107/S1744309109008549. Epub 2009 Mar 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19342788 Free PMC article.

2

1.8A X-ray structure of C95M/C1095F double mutant of tethered HIV-1 protease dimer complexed with acetyl pepstatin.

Prashar V, Hosur MV. Prashar V, et al. Biochem Biophys Res Commun. 2004 Oct 29;323(4):1229-35. doi: 10.1016/j.bbrc.2004.08.226. Biochem Biophys Res Commun. 2004. PMID: 15451428

3

Observation of a tetrahedral reaction intermediate in the HIV-1 protease-substrate complex.

Kumar M, Prashar V, Mahale S, Hosur MV. Kumar M, et al. Among authors: prashar v. Biochem J. 2005 Jul 15;389(Pt 2):365-71. doi: 10.1042/BJ20041804. Biochem J. 2005. PMID: 15794743 Free PMC article.

4

Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates.

Das A, Prashar V, Mahale S, Serre L, Ferrer JL, Hosur MV. Das A, et al. Among authors: prashar v. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18464-9. doi: 10.1073/pnas.0605809103. Epub 2006 Nov 20. Proc Natl Acad Sci U S A. 2006. PMID: 17116869 Free PMC article.

5

X-ray structure of HIV-1 protease in situ product complex.

Bihani S, Das A, Prashar V, Ferrer JL, Hosur MV. Bihani S, et al. Among authors: prashar v. Proteins. 2009 Feb 15;74(3):594-602. doi: 10.1002/prot.22174. Proteins. 2009. PMID: 18704947

6

Resistance mechanism revealed by crystal structures of unliganded nelfinavir-resistant HIV-1 protease non-active site mutants N88D and N88S.

Bihani SC, Das A, Prashar V, Ferrer JL, Hosur MV. Bihani SC, et al. Among authors: prashar v. Biochem Biophys Res Commun. 2009 Nov 13;389(2):295-300. doi: 10.1016/j.bbrc.2009.08.138. Epub 2009 Aug 29. Biochem Biophys Res Commun. 2009. PMID: 19720046

7

Crystallization and preliminary X-ray crystallographic analysis of PhoK, an extracellular alkaline phosphatase from Sphingomonas sp. BSAR-1.

Nilgiriwala KS, Bihani SC, Das A, Prashar V, Kumar M, Ferrer JL, Apte SK, Hosur MV. Nilgiriwala KS, et al. Among authors: prashar v. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Sep 1;65(Pt 9):917-9. doi: 10.1107/S1744309109031133. Epub 2009 Aug 22. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19724132 Free PMC article.

8

Catalytic water co-existing with a product peptide in the active site of HIV-1 protease revealed by X-ray structure analysis.

Prashar V, Bihani S, Das A, Ferrer JL, Hosur M. Prashar V, et al. PLoS One. 2009 Nov 17;4(11):e7860. doi: 10.1371/journal.pone.0007860. PLoS One. 2009. PMID: 19924250 Free PMC article.

9

X-ray snapshot of HIV-1 protease in action: observation of tetrahedral intermediate and short ionic hydrogen bond SIHB with catalytic aspartate.

Das A, Mahale S, Prashar V, Bihani S, Ferrer JL, Hosur MV. Das A, et al. Among authors: prashar v. J Am Chem Soc. 2010 May 12;132(18):6366-73. doi: 10.1021/ja100002b. J Am Chem Soc. 2010. PMID: 20397633

10

Insights into the mechanism of drug resistance: X-ray structure analysis of G48V/C95F tethered HIV-1 protease dimer/saquinavir complex.

Prashar V, Bihani SC, Das A, Rao DR, Hosur MV. Prashar V, et al. Biochem Biophys Res Commun. 2010 Jun 11;396(4):1018-23. doi: 10.1016/j.bbrc.2010.05.049. Epub 2010 May 13. Biochem Biophys Res Commun. 2010. PMID: 20471372

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