Precise microinjection into skin using hollow microneedles.
J Invest Dermatol. 2006.
PMID: 16484988
Search Page
Filters
Results by year
Table representation of search results timeline featuring number of search results per year.
| Year | Number of Results |
|---|---|
| 2006 | 1 |
| 2016 | 1 |
| 2017 | 3 |
| 2018 | 1 |
| 2024 | 1 |
| 2025 | 2 |
Search Results
7 results
Results by year
Citations
1
article
found by citation matching
Search results
Page 1
Precise microinjection into skin using hollow microneedles.
J Invest Dermatol. 2006 May;126(5):1080-7. doi: 10.1038/sj.jid.5700150.
J Invest Dermatol. 2006.
PMID: 16484988
Free article.
However, little work has been carried out to identify methods to effectively use hollow microneedles for drug delivery. To address this need, we inserted hollow, glass microneedles into hairless rat skin in vivo and human cadaver skin in …
However, little work has been carried out to identify methods to effectively use hollow microneedles for drug delivery. To add …
Intradermal vaccination with hollow microneedles: A comparative study of various protein antigen and adjuvant encapsulated nanoparticles.
J Control Release. 2017 Nov 28;266:109-118. doi: 10.1016/j.jconrel.2017.09.021. Epub 2017 Sep 21.
J Control Release. 2017.
PMID: 28943194
Free article.
The developed nanoparticles were loaded with a model antigen (ovalbumin (OVA)) with and without an adjuvant (poly(I:C)), followed by the characterization of size, zeta potential, morphology, and loading and release of antigen and adjuvant. An in-house developed hollow-m …
The developed nanoparticles were loaded with a model antigen (ovalbumin (OVA)) with and without an adjuvant (poly(I:C)), followed by the cha …
Hollow microneedle-mediated micro-injections of a liposomal HPV E7(43-63) synthetic long peptide vaccine for efficient induction of cytotoxic and T-helper responses.
J Control Release. 2018 Jan 10;269:347-354. doi: 10.1016/j.jconrel.2017.11.035. Epub 2017 Nov 22.
J Control Release. 2018.
PMID: 29174441
Free article.
Therefore, in the present study a digitally controlled hollow microneedle injection system (DC-hMN-iSystem) with an ultra-low dead volume was developed to perform micro-injections (0.25-10muL) into skin in an automated manner. ...Upon piercing these micron …
Therefore, in the present study a digitally controlled hollow microneedle injection system (DC-hMN-iSystem) with an ultra-low …
Hollow microneedle-mediated intradermal delivery of model vaccine antigen-loaded PLGA nanoparticles elicits protective T cell-mediated immunity to an intracellular bacterium.
J Control Release. 2017 Nov 28;266:27-35. doi: 10.1016/j.jconrel.2017.09.017. Epub 2017 Sep 14.
J Control Release. 2017.
PMID: 28917531
Free article.
Hollow microneedles allow for precise and non-invasive intradermal delivery of vaccines. ...Taken together, we show that PLGA nanoparticle formulation is an excellent delivery system for protein antigen into the skin and that protective cellular immune …
Hollow microneedles allow for precise and non-invasive intradermal delivery of vaccines. ...Taken together, we show tha …
Design and optimization of hollow microneedle spacing for three materials using finite element methods.
Sci Rep. 2025 Jan 3;15(1):652. doi: 10.1038/s41598-024-82564-8.
Sci Rep. 2025.
PMID: 39753609
Free PMC article.
The main advantages of microneedles are precise drug delivery through human skin, minimal tissue damage and painlessness. We conducted structural analysis and skin puncture studies of hollow microneedles using ANSYS for three materials: H …
The main advantages of microneedles are precise drug delivery through human skin, minimal tissue damage and painlessnes …
Advanced transdermal drug delivery system: A comprehensive review of microneedle technologies, novel designs, diverse applications, and critical challenges.
Int J Pharm. 2025 Feb 10;670:125118. doi: 10.1016/j.ijpharm.2024.125118. Epub 2024 Dec 20.
Int J Pharm. 2025.
PMID: 39710310
Review.
This innovative technology boasts a captivating profile characterized by non-invasive drug delivery, enhanced efficacy and onset time, improved patient acceptability, self-administration possibilities, and precise dosing capabilities. Consequently, both academic institutio …
This innovative technology boasts a captivating profile characterized by non-invasive drug delivery, enhanced efficacy and onset time, impro …
Repeated fractional intradermal dosing of an inactivated polio vaccine by a single hollow microneedle leads to superior immune responses.
J Control Release. 2016 Nov 28;242:141-147. doi: 10.1016/j.jconrel.2016.07.055. Epub 2016 Aug 2.
J Control Release. 2016.
PMID: 27496634
By utilizing an applicator that allowed for precisely controlled intradermal microinjections by using a single hollow microneedle, rats were immunized intradermally with 5 D-antigen units (DU) of IPV1 at 150mum skin depth. ...
By utilizing an applicator that allowed for precisely controlled intradermal microinjections by using a single hollow …
Cite