Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective.
Riedmaier AE, DeMent K, Huckle J, Bransford P, Stillhart C, Lloyd R, Alluri R, Basu S, Chen Y, Dhamankar V, Dodd S, Kulkarni P, Olivares-Morales A, Peng CC, Pepin X, Ren X, Tran T, Tistaert C, Heimbach T, Kesisoglou F, Wagner C, Parrott N.
Riedmaier AE, et al.
AAPS J. 2020 Sep 27;22(6):123. doi: 10.1208/s12248-020-00508-2.
AAPS J. 2020.
PMID: 32981010
Free PMC article.
The effect of food on pharmacokinetic properties of drugs is a commonly observed occurrence affecting about 40% of orally administered drugs. Within the pharmaceutical industry, significant resources are invested to predict and characterize a clinicall …
The effect of food on pharmacokinetic properties of drugs is a commonly observed occurrence affecting about 40% of oral …