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Bone marrow transplantation as a strategy for tolerance induction in the clinic.
Pree I, Pilat N, Wekerle T. Pree I, et al. Front Biosci (Landmark Ed). 2009 Jan 1;14:611-20. doi: 10.2741/3267. Front Biosci (Landmark Ed). 2009. PMID: 19273089 Review.
Murine mobilized peripheral blood stem cells have a lower capacity than bone marrow to induce mixed chimerism and tolerance.
Koporc Z, Pilat N, Nierlich P, Blaha P, Bigenzahn S, Pree I, Selzer E, Sykes M, Muehlbacher F, Wekerle T. Koporc Z, et al. Am J Transplant. 2008 Oct;8(10):2025-36. doi: 10.1111/j.1600-6143.2008.02371.x. Am J Transplant. 2008. PMID: 18828766 Free PMC article.
Inducing mixed chimerism and transplantation tolerance through allogeneic bone marrow transplantation with costimulation blockade.
Pree I, Wekerle T. Pree I, et al. Methods Mol Biol. 2007;380:391-403. doi: 10.1007/978-1-59745-395-0_25. Methods Mol Biol. 2007. PMID: 17876108 Review.
Induction of mixed chimerism (i.e., coexistence of donor and recipient hematopoietic cells) through transplantation of allogeneic donor bone marrow under appropriate host conditioning, is one of the most reliable strategies to induce transplantation tolerance. ...
Induction of mixed chimerism (i.e., coexistence of donor and recipient hematopoietic cells) through transplantation of allogeneic don …
Recent progress in tolerance induction through mixed chimerism.
Pree I, Pilat N, Wekerle T. Pree I, et al. Int Arch Allergy Immunol. 2007;144(3):254-66. doi: 10.1159/000104740. Epub 2007 Jun 27. Int Arch Allergy Immunol. 2007. PMID: 17596699 Review.
The role of non-deletional tolerance mechanisms in a murine model of mixed chimerism with costimulation blockade.
Bigenzahn S, Blaha P, Koporc Z, Pree I, Selzer E, Bergmeister H, Wrba F, Heusser C, Wagner K, Muehlbacher F, Wekerle T. Bigenzahn S, et al. Am J Transplant. 2005 Jun;5(6):1237-47. doi: 10.1111/j.1600-6143.2005.00862.x. Am J Transplant. 2005. PMID: 15888027
CTLA4Ig promotes the induction of hematopoietic chimerism and tolerance independently of Indoleamine-2,3-dioxygenase.
Pree I, Bigenzahn S, Fuchs D, Koporc Z, Nierlich P, Winkler C, Brandacher G, Sykes M, Muehlbacher F, Langer F, Wekerle T. Pree I, et al. Transplantation. 2007 Mar 15;83(5):663-7. doi: 10.1097/ Transplantation. 2007. PMID: 17353791 Free PMC article.
The role of natural killer T cells in costimulation blockade-based mixed chimerism.
Nierlich PN, Klaus C, Bigenzahn S, Pilat N, Koporc Z, Pree I, Baranyi U, Taniguchi M, Muehlbacher F, Wekerle T. Nierlich PN, et al. Transpl Int. 2010 Nov;23(11):1179-89. doi: 10.1111/j.1432-2277.2010.01120.x. Transpl Int. 2010. PMID: 20536788 Free PMC article.
Minor Antigen Disparities Impede Induction of Long Lasting Chimerism and Tolerance through Bone Marrow Transplantation with Costimulation Blockade.
Bigenzahn S, Pree I, Klaus C, Pilat N, Mahr B, Schwaiger E, Nierlich P, Wrba F, Wekerle T. Bigenzahn S, et al. Among authors: pree i. J Immunol Res. 2016;2016:8635721. doi: 10.1155/2016/8635721. Epub 2016 Oct 31. J Immunol Res. 2016. PMID: 27872868 Free PMC article.
Analysis of epitope-specific immune responses induced by vaccination with structurally folded and unfolded recombinant Bet v 1 allergen derivatives in man.
Pree I, Reisinger J, Focke M, Vrtala S, Pauli G, van Hage M, Cromwell O, Gadermaier E, Egger C, Reider N, Horak F, Valenta R, Niederberger V. Pree I, et al. J Immunol. 2007 Oct 15;179(8):5309-16. doi: 10.4049/jimmunol.179.8.5309. J Immunol. 2007. PMID: 17911617 Clinical Trial.
Inhibition of CD23-dependent facilitated allergen binding to B cells following vaccination with genetically modified hypoallergenic Bet v 1 molecules.
Pree I, Shamji MH, Kimber I, Valenta R, Durham SR, Niederberger V. Pree I, et al. Clin Exp Allergy. 2010 Sep;40(9):1346-52. doi: 10.1111/j.1365-2222.2010.03548.x. Epub 2010 Jun 28. Clin Exp Allergy. 2010. PMID: 20604801
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